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Author: Cornejo Bravo José Publisher: ISBN: Category : Science Languages : en Pages :
Book Description
Electrospinning is a very versatile techniqueused for many purposes, such as tissue engineering, textiles, air and water treatment filter, solar cells, and drug delivery systems, among others. This method is cheap, easy to handle, reproducible when ambient parameters are controlled, and can be used for many formulations. The objective of this review is to enlist and emphasize the advantages and disadvantages of different methods for incorporating therapeutic drugs in a drug delivery system with electrospinning. The importance of the research to create new and innovative drug carriers is high, because of their efficiency of transporting the bioactive agent to the target zone, avoiding secondary effects in the body. Nanofibers and nanoparticles have become an important strategy in pharmacology due to their physicochemical and biocompatible properties useful for this purpose. Among the techniques compared are blending coaxial, emulsion and surface modification electrospinning, followed by electrospray and coaxial electrospray. The present review concludes that every technique has advantages and disadvantages and, not all drugs can be loaded with any method, the strategy used will depend on the drug's physicochemical properties, target zone, polymeric characteristics, and required drug release rate. This chapter will serve as a starting point for when to choose one of the drug incorporation techniques mentioned.
Author: Cornejo Bravo José Publisher: ISBN: Category : Science Languages : en Pages :
Book Description
Electrospinning is a very versatile techniqueused for many purposes, such as tissue engineering, textiles, air and water treatment filter, solar cells, and drug delivery systems, among others. This method is cheap, easy to handle, reproducible when ambient parameters are controlled, and can be used for many formulations. The objective of this review is to enlist and emphasize the advantages and disadvantages of different methods for incorporating therapeutic drugs in a drug delivery system with electrospinning. The importance of the research to create new and innovative drug carriers is high, because of their efficiency of transporting the bioactive agent to the target zone, avoiding secondary effects in the body. Nanofibers and nanoparticles have become an important strategy in pharmacology due to their physicochemical and biocompatible properties useful for this purpose. Among the techniques compared are blending coaxial, emulsion and surface modification electrospinning, followed by electrospray and coaxial electrospray. The present review concludes that every technique has advantages and disadvantages and, not all drugs can be loaded with any method, the strategy used will depend on the drug's physicochemical properties, target zone, polymeric characteristics, and required drug release rate. This chapter will serve as a starting point for when to choose one of the drug incorporation techniques mentioned.
Author: Romána Zelkó Publisher: MDPI ISBN: 3039281402 Category : Medical Languages : en Pages : 206
Book Description
Several promising techniques have been developed to overcome the poor solubility and/or membrane permeability properties of new drug candidates, including different fiber formation methods. Electrospinning is one of the most commonly used spinning techniques for fiber formation, induced by the high voltage applied to the drug-loaded solution. With modifying the characteristics of the solution and the spinning parameters, the functionality-related properties of the formulated fibers can be finely tuned. The fiber properties (i.e., high specific surface area, porosity, and the possibility of controlling the crystalline–amorphous phase transitions of the loaded drugs) enable the improved rate and extent of solubility, causing a rapid onset of absorption. However, the enhanced molecular mobility of the amorphous drugs embedded into the fibers is also responsible for their physical–chemical instability. This Special Issue will address new developments in the area of electrospun nanofibers for drug delivery and wound healing applications, covering recent advantages and future directions in electrospun fiber formulations and scalability. Moreover, it serves to highlight and capture the contemporary progress in electrospinning techniques, with particular attention to the industrial feasibility of developing pharmaceutical dosage forms. All aspects of small molecule or biologics-loaded fibrous dosage forms, focusing on the processability, structures and functions, and stability issues, are included.
Author: Sajjad Haider Publisher: BoD – Books on Demand ISBN: 9535128213 Category : Science Languages : en Pages : 168
Book Description
This is a timely, an informative, an interesting, and a well-managed book. The book not only offers an in-depth review of the current status of the knowledge of electrospinning and its biomedical applications but also discusses the emerging ideas and features, both from the East and West, with a focus on the needless electrospinning for the production of uniform fibers. The book is equally helpful to the experts of this field, who wish to enhance their understanding of the emerging technologies, and to the new comers, who can use this book as a reference.
Author: Mehdi Afshari Publisher: Woodhead Publishing ISBN: 0081009119 Category : Technology & Engineering Languages : en Pages : 650
Book Description
Electrospun Nanofibers covers advances in the electrospinning process including characterization, testing and modeling of electrospun nanofibers, and electrospinning for particular fiber types and applications. Electrospun Nanofibers offers systematic and comprehensive coverage for academic researchers, industry professionals, and postgraduate students working in the field of fiber science. Electrospinning is the most commercially successful process for the production of nanofibers and rising demand is driving research and development in this field. Rapid progress is being made both in terms of the electrospinning process and in the production of nanofibers with superior chemical and physical properties. Electrospinning is becoming more efficient and more specialized in order to produce particular fiber types such as bicomponent and composite fibers, patterned and 3D nanofibers, carbon nanofibers and nanotubes, and nanofibers derived from chitosan. Provides systematic and comprehensive coverage of the manufacture, properties, and applications of nanofibers Covers recent developments in nanofibers materials including electrospinning of bicomponent, chitosan, carbon, and conductive fibers Brings together expertise from academia and industry to provide comprehensive, up-to-date information on nanofiber research and development Offers systematic and comprehensive coverage for academic researchers, industry professionals, and postgraduate students working in the field of fiber science
Author: Sajjad Haider Publisher: BoD – Books on Demand ISBN: 1789847001 Category : Science Languages : en Pages : 122
Book Description
This book focuses on the recent advancements in the process parameters, research, and applications of electrospinning and electrospraying. The first chapter introduces the techniques and the effect of the parameters on the morphology of the nanofiber and nanoparticles and then the subsequent chapters focus on the applications of these techniques in different areas. This book will attract a broad audience including postgraduate students and industrial and academic investigators in sciences and engineering who wish to enhance their understanding of the emerging technologies and use this book as reference.
Author: Romána Zelkó Publisher: ISBN: 9783039281411 Category : Medicine (General) Languages : en Pages : 206
Book Description
Several promising techniques have been developed to overcome the poor solubility and/or membrane permeability properties of new drug candidates, including different fiber formation methods. Electrospinning is one of the most commonly used spinning techniques for fiber formation, induced by the high voltage applied to the drug-loaded solution. With modifying the characteristics of the solution and the spinning parameters, the functionality-related properties of the formulated fibers can be finely tuned. The fiber properties (i.e., high specific surface area, porosity, and the possibility of controlling the crystalline-amorphous phase transitions of the loaded drugs) enable the improved rate and extent of solubility, causing a rapid onset of absorption. However, the enhanced molecular mobility of the amorphous drugs embedded into the fibers is also responsible for their physical-chemical instability. This Special Issue will address new developments in the area of electrospun nanofibers for drug delivery and wound healing applications, covering recent advantages and future directions in electrospun fiber formulations and scalability. Moreover, it serves to highlight and capture the contemporary progress in electrospinning techniques, with particular attention to the industrial feasibility of developing pharmaceutical dosage forms. All aspects of small molecule or biologics-loaded fibrous dosage forms, focusing on the processability, structures and functions, and stability issues, are included.
Author: Chandrasekar Muthukumar Publisher: CRC Press ISBN: 1000988295 Category : Science Languages : en Pages : 368
Book Description
Electrospinning is a versatile method to synthesize fiber materials. Electrospun Nanofibres: Materials, Methods, and Applications explores the technical aspects of electrospinning methods used to derive a wide range of functional fiber materials and their applications in various technical sectors. As electrospinning is a process that can be modified strategically to achieve different fibers of interest, this book covers the wide spectrum of electrospinning methodologies, such as coaxial, triaxial, emulsion, suspension, electrolyte and gas-assisted spinning processes. It: • Discusses a broad range of materials, including synthetic polymers, biodegradable polymers, metals and their oxides, hybrid materials, nonpolymers, and more. • Reviews different electrospinning methods and combined technologies. • Describes process-related parameters and their influence on material properties and performance. • Examines modeling of the electrospinning process. • Highlights applications across different industries. This book is aimed at researchers, professionals, and advanced students in materials science and engineering.
Author: Inamuddin Publisher: John Wiley & Sons ISBN: 1119654866 Category : Technology & Engineering Languages : en Pages : 544
Book Description
The aim of this book is to explore the history, fundamentals, manufacturing processes, optimization parameters, and applications of electrospun materials. The book includes various types of electrospun materials such as antimicrobial, smart, bioinspired systems. It focuses on the many application areas for electrospun materials such as energy storage and harvesting, catalysis, biomedical including gene delivery and tissue engineering, separation, adsorption and water treatment technologies, packaging. The book emphasizes the enhanced sustainable properties of electrospun materials, with the challenges and future developments being discussed in detail. The chapters are written by top-class researchers and experts from throughout the world.
Author: L Bosworth Publisher: Elsevier ISBN: 085709291X Category : Technology & Engineering Languages : en Pages : 425
Book Description
Electrospinning is a simple and highly versatile method for generating ultrathin fibres with diameters ranging from a few micrometres to tens of nanometres. Although most commonly associated with textile manufacturing, recent research has proved that the electrospinning technology can be used to create organ components and repair damaged tissues. Electrospinning for tissue regeneration provides a comprehensive overview of this innovative approach to tissue repair and regeneration and examines how it is being employed within the biomaterials sector.The book opens with an introduction to the fundamentals of electrospinning. Chapters go on to discuss polymer chemistry, the electrospinning process, conditions, control and regulatory issues. Part two focuses specifically on electrospinning for tissue regeneration and investigates its uses in bone, cartilage, muscle, tendon, nerve, heart valve, bladder, tracheal, dental and skin tissue regeneration before concluding with a chapter on wound dressings. Part three explores electrospinning for in vitro applications. Chapters discuss cell culture systems for kidney, pancreatic and stem cell research.With its distinguished editors and international team of expert contributors, Electrospinning for tissue regeneration is a valuable reference tool for those in academia and industry concerned with research and development in the field of tissue repair and regeneration. Provides a comprehensive overview of this innovative approach to tissue repair and regeneration covering issues from polymer chemistry to the regulatory process Examines employment within the biomaterials sector, reviewing extensive applications in areas such as uses in bone, muscle tendon, heart valve and tissue regeneration Explores electrospinning for in vitro applications and discusses cell culture systems for kidney, pancreatic and stem cell research
Author: Dennis M. Brown Publisher: Springer Science & Business Media ISBN: 1592594271 Category : Medical Languages : en Pages : 438
Book Description
Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.
Author: Cornejo Bravo José
Author: Cornejo Bravo José
Author: Romána Zelkó
Author: Sajjad Haider
Author: Mehdi Afshari
Author: Sajjad Haider
Author: Romána Zelkó
Author: Chandrasekar Muthukumar
Author: Inamuddin
Author: L Bosworth
Author: Dennis M. Brown