The Poisoner's Handbook PDF Download

Author: Deborah Blum
Publisher: Penguin
ISBN: 1101524898
Category : Medical
Languages : en
Pages : 338

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Book Description
Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer “The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times “Reads like science fiction, complete with suspense, mystery and foolhardy guys in lab coats tipping test tubes of mysterious chemicals into their own mouths.” —NPR: What We're Reading A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice. In 2014, PBS's AMERICAN EXPERIENCE released a film based on The Poisoner's Handbook.

Author: Suzanne Bell
Publisher: Infobase Holdings, Inc
ISBN: 1438182600
Category : Science
Languages : en
Pages : 126

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Book Description
Forensic chemists and toxicologists work with drugs and poisons, but they each start with different evidence. Forensic chemists working in a crime lab must determine if the physical evidence they receive is an illegal substance such as marijuana or cocaine. They are also responsible for samples—including fire debris, soil, paint, glass, explosives, and fibers—obtained from suspected arson crimes. Toxicologists, on the other hand, work with biological evidence such as blood, saliva, urine, and feces, using analytical chemistry to identify chemical traces and unmetabolized drugs. They often work in labs associated with a medical examiner’s office or a hospital. Drugs, Poisons, and Chemistry, Revised Edition touches on all aspects of forensic chemistry, including how it developed and what it includes today. This useful eBook covers a short history of forensic chemistry, detailing the story of arsenic and those who developed effective tests to detect it. Delving into the tools and techniques used by forensic chemists—ranging from such familiar tools as the microscope to slightly more obscure tools as the use of antibodies to detect toxins—this comprehensive resource provides a thorough examination of these three main areas of forensic chemistry. Chapters include: History and Pioneers Scientific Principles, Instrumentation, and Equipment Toxicology: Drugs and Poisons in the Body Forensic Drug Analysis Conclusions: The Future of Drugs, Poisons, and Chemistry.

Author: A. C. Moffat
Publisher:
ISBN:
Category : Analytical toxicology
Languages : en
Pages : 680

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Book Description
This manual and reference work provides a source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying a drug in a pharmaceutical product, in a sample of tissue or body fluid, from a living patient or in post-mortem material. Volume One contains 32 chapters covering the practice of and analytical procedures used in forensic toxicology. Volume Two contains over 1750 drug and related substance monographs detailing: physical properties; analytical methods; pharmacokinetic data; and toxicity data, as well as expanded indexes and appendices. These volumes should be useful for all forensic and crime laboratories, toxicologists and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.

Author: Olen R. Brown
Publisher: Bentham Science Publishers
ISBN: 1681086972
Category : Science
Languages : en
Pages : 282

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Book Description
Poisons, due to their lethal nature, invoke a sense of fear in humans. Yet, they have also impacted other aspects of human life. Poisons have been used by nomadic hunters to kill their prey, by scientists to explore complex biochemical mechanisms of the body, by physicians to lower cholesterol and to kill cancer cells, by farmers and the general public to destroy pests, by the evil minded for homicide, and by tyrants as weapons of war. The Art and Science of Poisons presents two facets of poisons: the science behind them and their place in history and art. The science of poisons describes their biochemistry and how they kill. The science story voyages into the sub-microscopic world of atoms, molecules, and cells. Only there can we see the true miracles and mysteries of life and death. Chapters in the book explore poisons from snakes, spiders, scorpions, sea creatures, as well as poisons made by humans in the laboratory, and those which are derived from beautiful plants. The art of poisons, on the other hand, encompasses everything else about these agents that conjures up the image of the skull and crossbones. This side of the story explores the legends and tales of intrigue and surreptitious deaths of well-known personalities such as Socrates, Cleopatra, Hitler, and many more. General readers with a curiosity about science and an interest in history and human nature will enjoy both facets presented in this brief, yet varied exploration into the world of poisons.

Author: Andrew G. Mtewa
Publisher: John Wiley & Sons
ISBN: 1119650232
Category : Science
Languages : en
Pages : 444

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Book Description
Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career

Author: Eustace George Coverley Clarke
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 1258

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Book Description
Provides the means to identify and quantify drugs and other toxic substances in situations of overdose or poisoning and to interpret analytical results. Includes an analysis of toxic metals and pesticides.

Author: John Timbrell
Publisher: Oxford University Press, USA
ISBN: 0192804952
Category : Language Arts & Disciplines
Languages : en
Pages : 362

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Book Description
Using reported disasters and everyday examples, this book examines both natural and man-made chemicals that we are exposed to. Illuminating the world of toxicology, it explains how they are toxic and the different reactions that individuals have to them. It also aims to debunk the popular belief that 'Natural is good, Man-made is bad'.

Author: Shinji Funayama
Publisher: Elsevier
ISBN: 0124173144
Category : Science
Languages : en
Pages : 295

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Book Description
Alkaloids are a large group of structurally complex natural products displaying a wide range of biological activities. The purpose of Alkaloids: A Treasury of Poisons and Medicines is to classify, for the first time, the alkaloids isolated from the natural sources until now. The book classifies all of the alkaloids by their biosynthetic origins. Of interest to the organic chemistry and medicinal chemistry communities involved in drug discovery and development, this book describes many alkaloids isolated from the medicinal plants, including those used in Japanese Kampo medicine. - Classifies and lists alkaloids from natural sources - Occurrence and biosynthetic pathways of alkaloids - Indicates key uses and bioactivity of alkaloids

Author: Robert J. Flanagan
Publisher: John Wiley & Sons
ISBN: 0470319348
Category : Science
Languages : en
Pages : 605

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Book Description
The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry

Author: Alisha Rankin
Publisher: University of Chicago Press
ISBN: 9780226744858
Category : Science
Languages : en
Pages : 0

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Book Description
In 1524, Pope Clement VII gave two condemned criminals to his physician to test a promising new antidote. After each convict ate a marzipan cake poisoned with deadly aconite, one of them received the antidote, and lived—the other died in agony. In sixteenth-century Europe, this and more than a dozen other accounts of poison trials were committed to writing. Alisha Rankin tells their little-known story. At a time when poison was widely feared, the urgent need for effective cures provoked intense excitement about new drugs. As doctors created, performed, and evaluated poison trials, they devoted careful attention to method, wrote detailed experimental reports, and engaged with the problem of using human subjects for fatal tests. In reconstructing this history, Rankin reveals how the antidote trials generated extensive engagement with “experimental thinking” long before the great experimental boom of the seventeenth century and investigates how competition with lower-class healers spurred on this trend. The Poison Trials sheds welcome and timely light on the intertwined nature of medical innovations, professional rivalries, and political power.