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Drug Development and Conservation in West and Central Africa/Performance of Neurochemical and Radio Receptor Assays of Plant Extracts

Drug Development and Conservation in West and Central Africa/Performance of Neurochemical and Radio Receptor Assays of Plant Extracts PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Book Description
The main objective of these studies was to study the CNS activity of these plant fractions using specific radio ligand binding assays to identify their selectivity profiles as well as to determine their functional activities as either a full or partial agonist or antagonist.

Drug Development and Conservation in West and Central Africa/Performance of Neurochemical and Radio Receptor Assays of Plant Extracts

Drug Development and Conservation in West and Central Africa/Performance of Neurochemical and Radio Receptor Assays of Plant Extracts PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Book Description
The main objective of these studies was to study the CNS activity of these plant fractions using specific radio ligand binding assays to identify their selectivity profiles as well as to determine their functional activities as either a full or partial agonist or antagonist.

Drug Development and Conservation of Biodiversity in West and Central Africa: Performance of Neurochemical and Radio Receptor Assays of Plant Extracts Drug Discovery for the Central Nervous System

Drug Development and Conservation of Biodiversity in West and Central Africa: Performance of Neurochemical and Radio Receptor Assays of Plant Extracts Drug Discovery for the Central Nervous System PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 34

Book Description
The thrust of the CNS assay panel was to identify plant extracts that display moderate to high affinity for selected molecular targets. Target selection was based identifying active plant extracts that would be useful for one or more neuropsyschiatric disorders. We completed a screen for 102 samples belonging to 43 plants. 41 showed activity at one or more CNS targets. Phytochemical studies have been initiated on several active extracts. A total of 12 plants samples which have tested positive for antiplasmodial activity were collected in bulk quantities for detailed phytochemical investigations into antimalarial and trypanocidal activity.

Drug Development and Conservation of Biodiversity in West and Central Africa

Drug Development and Conservation of Biodiversity in West and Central Africa PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 20

Book Description
This report concerns activities of Associated Project #3 (AP#3) of the International Cooperative Biodiversity Group Program (ICBC) directed by the Walter Reed Army Institute for Research (WRAIR). This project examines medicinal plants of Central and West Africa as anti-typanosomal and anti-trichomonal agents. In the reporting period 85 plant extracts were received from WRAIR and 34 were received from the University of Dschang (Cameroon, AP#2). Extracts were screened in vitro vs. blood stream forms of African trypanosomes (Trypanosoma brucei, Trypanosoma rhodesiense) and pathogenic trichomonads (Trichomonas vaginalis, Tritrichomonas foetus). In the trypanosome growth screen, 58 WRAIR extracts and 8 AP#2 extracts were tested. Eight WRAIR extracts were tested vs metronidazole-resistant and -sensitive strains of T. vaginalis and another 31 were studied in a T. foetus screen. Of 58 WRAIR extracts tested 24 had IC50 values

Natural Products Chemistry of Botanical Medicines from Cameroonian Plants

Natural Products Chemistry of Botanical Medicines from Cameroonian Plants PDF Author: Xavier Siwe-Noundou
Publisher: CRC Press
ISBN: 0429015216
Category : Science
Languages : en
Pages : 221

Book Description
Forms an important part of the series on Natural Products Chemistry of Global Plants, as Cameroon is a country with rich experience in the use of medicinal plants and with a wide diversity of botanical resources Addresses the current development of pharmacognostic research in Cameroon Provides readers with updated information on the chemistry and pharmacology of natural products with pharmaceutical potentials Covers an extensive range of chemical, botanical and pharmacological diversities

Tolerable upper intake levels for vitamins and minerals

Tolerable upper intake levels for vitamins and minerals PDF Author: European Commission. Scientific Committee on Food
Publisher:
ISBN: 9789291990146
Category : Dietary supplements
Languages : en
Pages : 478

Book Description


Toxicological Profile for Thorium

Toxicological Profile for Thorium PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Book Description


How to Change Your Mind

How to Change Your Mind PDF Author: Michael Pollan
Publisher: Penguin
ISBN: 0735224153
Category : Body, Mind & Spirit
Languages : en
Pages : 481

Book Description
Now on Netflix as a 4-part documentary series! “Pollan keeps you turning the pages . . . cleareyed and assured.” —New York Times A #1 New York Times Bestseller, New York Times Book Review 10 Best Books of 2018, and New York Times Notable Book A brilliant and brave investigation into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists inadvertently catalyzed a powerful backlash against what was then a promising field of research. A unique and elegant blend of science, memoir, travel writing, history, and medicine, How to Change Your Mind is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both suffering and joy, we can do our best to be fully present and find meaning in our lives.

Classification of Instructional Programs

Classification of Instructional Programs PDF Author: Robert L. Morgan
Publisher:
ISBN:
Category : Education
Languages : en
Pages : 438

Book Description


Scientific Basis for Ayurvedic Therapies

Scientific Basis for Ayurvedic Therapies PDF Author: Lakshmi C. Mishra
Publisher: CRC Press
ISBN: 9780849313660
Category : Medical
Languages : en
Pages : 502

Book Description
Arguably the oldest form of health care, Ayurveda is often referred to as the "Mother of All Healing." Although there has been considerable scientific research done in this area during the last 50 years, the results of that research have not been adequately disseminated. Meeting the need for an authoritative, evidence-based reference, Scientific Basis for Ayurvedic Therapies is the first book to analyze and synthesize current research supporting Ayurvedic medicine. This book reviews the latest scientific information, evaluates the research data, and presents it in an easy to use format. The editor has carefully selected topics based on the availability of scientific studies and the prevalence of a disease. With contributions from experts in their respective fields, topics include Ayurvedic disease management, panchkarma, Ayurvedic bhasmas, the current status of Ayurveda in India, clinical research design, and evaluation of typical clinical trials of certain diseases, to name just a few. While there are many books devoted to Ayurveda, very few have any in-depth basis in scientific studies. This book provides a critical evaluation of literature, clinical trials, and biochemical and pharmacological studies on major Ayurvedic therapies that demonstrates how they are supported by scientific data. Providing a natural bridge from Ayurveda to Western medicine, Scientific Basis for Ayurvedic Therapies facilitates the integration of these therapies by health care providers.

Homeostatic Control of Brain Function

Homeostatic Control of Brain Function PDF Author: Detlev Boison
Publisher: Oxford University Press
ISBN: 0199322295
Category : Medical
Languages : en
Pages : 657

Book Description
Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.