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Pain Modulation

Pain Modulation PDF Author: Howard L. Fields
Publisher: Elsevier Publishing Company
ISBN: 9780444809841
Category : Medical
Languages : en
Pages : 454

Book Description
This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.

Pain Modulation

Pain Modulation PDF Author: Howard L. Fields
Publisher: Elsevier Publishing Company
ISBN: 9780444809841
Category : Medical
Languages : en
Pages : 454

Book Description
This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.

Sensory Mechanisms of the Spinal Cord

Sensory Mechanisms of the Spinal Cord PDF Author: William D. Willis Jr.
Publisher: Springer Science & Business Media
ISBN: 9780306480331
Category : Medical
Languages : en
Pages : 620

Book Description
The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy 4. The description of the dorsal hom in the previous Chapter 4 of these neurons in Chapter is now included in Chapter 5, and the chemical neuroanatomy of the dorsal hom in Chapter 6. Furthermore, discussions of the descending control systems have now been of Chapter 12. consolidated at the end The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.

Acute Pain Management

Acute Pain Management PDF Author: Raymond S. Sinatra
Publisher: Cambridge University Press
ISBN: 0521874912
Category : Medical
Languages : en
Pages : 729

Book Description
This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

Processing of Sensory Information in the Superficial Dorsal Horn of the Spinal Cord

Processing of Sensory Information in the Superficial Dorsal Horn of the Spinal Cord PDF Author: F. Cervero
Publisher: Springer Science & Business Media
ISBN: 1461308259
Category : Science
Languages : en
Pages : 508

Book Description
This book constitutes the proceedings of a NATO Advanced Research Workshop held in El Escorial (Spain) from 22 -27 May 1988 with the title Processing of sensory information in the superficial dorsal hom of the spinal cord. Included in the book are reports of most of the main lectures given at the meeting, section introductions written by each session Chairman, section reports compiled by session rapporteurs and some short papers invited from authors of communications given in poster form. The latter were selected on the basis of being immediately relevant to the topic of the workshop and of originating from a laboratory not represented by the main speakers. All in all we believe that the reader can get a fair idea of the structure and general character of this Workshop. The overall aim of the meeting was to review the current state of knowledge on the role of the superficial dorsal horn of the mammalian spinal cord as a nucleus of relay and modulation of the somatic and visceral sensory input to the central nervous system. In this context, the contribution of this spinal cord region to the appreciation of pain was a central topic of discussion. Over the last decade there has been a considerable increase in anatomical, physiological and neurochemical studies of the superficial dorsal horn.

Handbook of Spinal Cord Monitoring

Handbook of Spinal Cord Monitoring PDF Author: S.J. Jones
Publisher: Springer Science & Business Media
ISBN: 9401114161
Category : Medical
Languages : en
Pages : 460

Book Description
Surgery for the treatment of deformities such as scoliosis carries a small but significant risk of damage to the spinal cord through inadvertent compression or interference with the blood supply. Electrophysiological techniques, principally those for recording sensory and motor evoked potentials, offer a means of continuously assessing the conduction of nerve signals up and down the spinal cord and hence the possibility of detecting a defect at an early stage, when the cause may be reversible. This form of monitoring is now accepted practice in many countries. The main contributors to the Handbook are surgeons, neurophysiologists and anaesthetists at the forefront of research. From the United States, where practice has been most widespread, come the results of the first large-scale, multi-centre survey into monitoring methods and their effectiveness. The research papers forming the remainder of the text provide an indication of the high level of current interest and the likely direction of future developments.

Pain Medicine

Pain Medicine PDF Author: R. Jason Yong
Publisher: Springer
ISBN: 3319431331
Category : Medical
Languages : en
Pages : 540

Book Description
This book serves as a practical resource for pain medicine providers. It presents important clinical concepts while covering critical pain medicine fundamentals. Chapters were carefully chosen to cover common aspects of clinical pain medicine and also follow a common format to facilitate quick look-up. Each chapter includes a concise discussion of the latest supporting evidence as well as relevant case scenarios. The coverage is clinically and board relevant, evidence-based and up-to-date. It will appeal to residents preparing for the written board examination and practitioners preparing for board re-certification, which now occurs every 10 years. Beyond these groups, the book has the potential to appeal to learners and practitioners around the world; pain medicine is burgeoning globally, and there is great need for concise, clinically relevant resources.

Sensory Mechanisms of the Spinal Cord

Sensory Mechanisms of the Spinal Cord PDF Author: William D. Willis Jr.
Publisher: Springer Science & Business Media
ISBN: 1461500370
Category : Medical
Languages : en
Pages : 604

Book Description
The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy 4. The description of the dorsal hom in the previous Chapter 4 of these neurons in Chapter is now included in Chapter 5, and the chemical neuroanatomy of the dorsal hom in Chapter 6. Furthermore, discussions of the descending control systems have now been of Chapter 12. consolidated at the end The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.

Development of the Human Spinal Cord

Development of the Human Spinal Cord PDF Author: Joseph Altman
Publisher:
ISBN: 9780195144277
Category : Medical
Languages : en
Pages : 566

Book Description
There exists a wealth of information about the development of the spinal cord in journal articles and monographs, yet this beautifully illustrated work is the first book devoted to this important topic. Because the developing human spinal cord cannot be subjected to experimental manipulations, the knowledge gained from experimental work in animals is applied here to an interpretation of the time course and mechanisms of spinal cord development in man. The book begins with a review of our current understanding of the structure and functions of the spinal cord. Special reference is made to the phylogeny of the vertebrate spinal cord because the authors' interpretation of the development and organization of the human spinal cord is specifically an evolutionary one. Following a detailed experiment-based account of spinal cord development in the rat, the development of the human spinal cord is described, illustrated and interpreted in separate chapters during three epochs: the first trimester (the embryonic period), the second and third trimesters (the fetal period), and the first year of postnatal life. Special attention is paid to such topics as neurons, and the growth and myelination of the ascending and descending fiber tracts of the spinal cord. The book ends with a correlation of the development of motor behavior with different stages in the morphological development of the human spinal cord during the embryonic, fetal, and postnatal periods. The successive acquisition of voluntary control over different parts of the body during infancy is correlated with the progressive myelination of the corticospinal tract. * The book contains an extensive review of work on spinal cord organization and development throughout the 20th century. * The interpretations are based on experimental studies of spinal cord development in the rat carried out by the authors and their associates. * The histological material on human spinal cord development is the largest ever assembled and reproduced (combining the Carnegie, Minot, and Yakovlev Collections). * The collected material (which varies in quality and some of it has begun to fade) has been digitized and electronically reprocessed for improved reproduction. * Discrete components of the spinal cord and new developments are highlighted by color coding; typically on one side only, leaving the contralateral side untouched to allow the reader to use his own interpretation. * Summary graphs are presented, many in color, to convey important structural relationships, developmental events, or theories. * The authors revive a few forgotten theories and offer several new ones regarding the development and organization of the human spinal cord. Development of the Human Spinal Cord will be of interest to developmental biologists, neuroscientists, embryologists, molecular biologists (those working on stem cell research), pediatric neurologists, pathologists, child and developmental psychologists, and their students and trainees.

The Spinal Cord

The Spinal Cord PDF Author: Charles Watson
Publisher: Academic Press
ISBN: 0080921388
Category : Medical
Languages : en
Pages : 408

Book Description
Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN). - The text provides a detailed account of the anatomy of the mammalian spinal cord and surrounding musculoskeletal elements - The major topics addressed are: development of the spinal cord; the gross anatomy of the spinal cord and its meninges; spinal nerves, nerve roots, and dorsal root ganglia; the vertebral column, vertebral joints, and vertebral muscles; blood supply of the spinal cord; cytoarchitecture and chemoarchitecture of the spinal gray matter; musculotopic anatomy of motoneuron groups; tracts connecting the brain and spinal cord; spinospinal pathways; sympathetic and parasympathetic elements in the spinal cord; neuronal groups and pathways that control micturition; the anatomy of spinal cord injury in experimental animals - The atlas of the rat and mouse spinal cord has the following features: Photographs of Nissl stained transverse sections from each of 34 spinal segments for the rat and mouse; Detailed diagrams of each of the 34 spinal segments for rat and mouse, delineating the laminae of Rexed and all other significant neuronal groupings at each level. ; Alongside each of the 34 Nissl stained segments, there are additional sections displaying markers such as acetylcholinesterase, calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), and neuronal nuclear protein (NeuN) - All the major motoneuron clusters are identified in relation to the individual muscles or muscle groups they supply

The Mouse Nervous System

The Mouse Nervous System PDF Author: Charles Watson
Publisher: Academic Press
ISBN: 0123694973
Category : Medical
Languages : en
Pages : 815

Book Description
The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness