Design and Analysis of Experiments in the Health Sciences PDF Download

Author: Gerald van Belle
Publisher: John Wiley & Sons
ISBN: 0470127279
Category : Mathematics
Languages : en
Pages : 256

View

Book Description
An accessible and practical approach to the design and analysis of experiments in the health sciences Design and Analysis of Experiments in the Health Sciences provides a balanced presentation of design and analysis issues relating to data in the health sciences and emphasizes new research areas, the crucial topic of clinical trials, and state-of-the- art applications. Advancing the idea that design drives analysis and analysis reveals the design, the book clearly explains how to apply design and analysis principles in animal, human, and laboratory experiments while illustrating topics with applications and examples from randomized clinical trials and the modern topic of microarrays. The authors outline the following five types of designs that form the basis of most experimental structures: Completely randomized designs Randomized block designs Factorial designs Multilevel experiments Repeated measures designs A related website features a wealth of data sets that are used throughout the book, allowing readers to work hands-on with the material. In addition, an extensive bibliography outlines additional resources for further study of the presented topics. Requiring only a basic background in statistics, Design and Analysis of Experiments in the Health Sciences is an excellent book for introductory courses on experimental design and analysis at the graduate level. The book also serves as a valuable resource for researchers in medicine, dentistry, nursing, epidemiology, statistical genetics, and public health.

Author: Gerald van Belle
Publisher: John Wiley & Sons
ISBN: 1118279719
Category : Mathematics
Languages : en
Pages : 256

View

Book Description
An accessible and practical approach to the design and analysis of experiments in the health sciences Design and Analysis of Experiments in the Health Sciences provides a balanced presentation of design and analysis issues relating to data in the health sciences and emphasizes new research areas, the crucial topic of clinical trials, and state-of-the- art applications. Advancing the idea that design drives analysis and analysis reveals the design, the book clearly explains how to apply design and analysis principles in animal, human, and laboratory experiments while illustrating topics with applications and examples from randomized clinical trials and the modern topic of microarrays. The authors outline the following five types of designs that form the basis of most experimental structures: Completely randomized designs Randomized block designs Factorial designs Multilevel experiments Repeated measures designs A related website features a wealth of data sets that are used throughout the book, allowing readers to work hands-on with the material. In addition, an extensive bibliography outlines additional resources for further study of the presented topics. Requiring only a basic background in statistics, Design and Analysis of Experiments in the Health Sciences is an excellent book for introductory courses on experimental design and analysis at the graduate level. The book also serves as a valuable resource for researchers in medicine, dentistry, nursing, epidemiology, statistical genetics, and public health.

Author: Douglas C. Montgomery
Publisher: Wiley
ISBN: 9780471661597
Category : Experimental design
Languages : en
Pages : 0

View

Book Description
This bestselling professional reference has helped over 100,000 engineers and scientists with the success of their experiments. The new edition includes more software examples taken from the three most dominant programs in the field: Minitab, JMP, and SAS. Additional material has also been added in several chapters, including new developments in robust design and factorial designs. New examples and exercises are also presented to illustrate the use of designed experiments in service and transactional organizations. Engineers will be able to apply this information to improve the quality and efficiency of working systems.

Author: Richard McCleary
Publisher: Oxford University Press
ISBN: 0190661569
Category : Business & Economics
Languages : en
Pages : 393

View

Book Description
Design and Analysis of Time Series Experiments develops methods and models for analysis and interpretation of time series experiments while also addressing recent developments in causal modeling. Unlike other time series texts, it integrates the statistical issues of design, estimation, and interpretation with foundational validity issues. Drawing on examples from criminology, economics, education, pharmacology, public policy, program evaluation, public health, and psychology, this text addresses researchers and graduate students in a wide range of the behavioral, biomedical, and social sciences.

Author: Hans-Michael Kaltenbach
Publisher: Springer Nature
ISBN: 3030696413
Category : Mathematics
Languages : en
Pages : 281

View

Book Description
This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research. It covers the most common aspects of experimental design such as handling multiple treatment factors and improving precision. In addition, it addresses experiments with large numbers of treatment factors and response surface methods for optimizing experimental conditions or biotechnological yields. The book emphasizes the estimation of effect sizes and the principled use of statistical arguments in the broader scientific context. It gradually transitions from classical analysis of variance to modern linear mixed models, and provides detailed information on power analysis and sample size determination, including ‘portable power’ formulas for making quick approximate calculations. In turn, detailed discussions of several real-life examples illustrate the complexities and aberrations that can arise in practice. Chiefly intended for students, teachers and researchers in the fields of experimental biology and biomedicine, the book is largely self-contained and starts with the necessary background on basic statistical concepts. The underlying ideas and necessary mathematics are gradually introduced in increasingly complex variants of a single example. Hasse diagrams serve as a powerful method for visualizing and comparing experimental designs and deriving appropriate models for their analysis. Manual calculations are provided for early examples, allowing the reader to follow the analyses in detail. More complex calculations rely on the statistical software R, but are easily transferable to other software. Though there are few prerequisites for effectively using the book, previous exposure to basic statistical ideas and the software R would be advisable.

Author: Charles S. Reichardt
Publisher: Guilford Publications
ISBN: 1462540201
Category : Business & Economics
Languages : en
Pages : 382

View

Book Description
Featuring engaging examples from diverse disciplines, this book explains how to use modern approaches to quasi-experimentation to derive credible estimates of treatment effects under the demanding constraints of field settings. Foremost expert Charles S. Reichardt provides an in-depth examination of the design and statistical analysis of pretest-posttest, nonequivalent groups, regression discontinuity, and interrupted time-series designs. He details their relative strengths and weaknesses and offers practical advice about their use. Reichardt compares quasi-experiments to randomized experiments and discusses when and why the former might be a better choice. Modern moethods for elaborating a research design to remove bias from estimates of treatment effects are described, as are tactics for dealing with missing data and noncompliance with treatment assignment. Throughout, mathematical equations are translated into words to enhance accessibility.

Author: John Lawson
Publisher: CRC Press
ISBN: 1498728480
Category : Mathematics
Languages : en
Pages : 629

View

Book Description
Design and Analysis of Experiments with R presents a unified treatment of experimental designs and design concepts commonly used in practice. It connects the objectives of research to the type of experimental design required, describes the process of creating the design and collecting the data, shows how to perform the proper analysis of the data,

Author: Trevor Raymond Morris
Publisher: Cabi
ISBN:
Category : Medical
Languages : en
Pages : 226

View

Book Description
Experimental Design and Analysis in Animals Sciences is the first book to provide detailed instructions on the design and analysis of experiments in animals sciences. Not only does it provide descriptions of the statistics of experiment design, this guide-book contains examples and suggestions that help students in their decisions on which tools are appropriate for each circumstance. The subjects covered include interpretation of dose-response experiments, change-over designs, experiments with animals in pens and paddocks, and balanced and unbalanced designs. This book will be indispensable for any graduate or advanced undergraduate student in the animal sciences.

Author: Angela Dean
Publisher: CRC Press
ISBN: 146650434X
Category : Mathematics
Languages : en
Pages : 946

View

Book Description
This carefully edited collection synthesizes the state of the art in the theory and applications of designed experiments and their analyses. It provides a detailed overview of the tools required for the optimal design of experiments and their analyses. The handbook covers many recent advances in the field, including designs for nonlinear models and algorithms applicable to a wide variety of design problems. It also explores the extensive use of experimental designs in marketing, the pharmaceutical industry, engineering and other areas.

Author: John H. Skillings
Publisher: Routledge
ISBN: 1351469975
Category : Mathematics
Languages : en
Pages : 696

View

Book Description
Most texts on experimental design fall into one of two distinct categories. There are theoretical works with few applications and minimal discussion on design, and there are methods books with limited or no discussion of the underlying theory. Furthermore, most of these tend to either treat the analysis of each design separately with little attempt to unify procedures, or they will integrate the analysis for the designs into one general technique. A First Course in the Design of Experiments: A Linear Models Approach stands apart. It presents theory and methods, emphasizes both the design selection for an experiment and the analysis of data, and integrates the analysis for the various designs with the general theory for linear models. The authors begin with a general introduction then lead students through the theoretical results, the various design models, and the analytical concepts that will enable them to analyze virtually any design. Rife with examples and exercises, the text also encourages using computers to analyze data. The authors use the SAS software package throughout the book, but also demonstrate how any regression program can be used for analysis. With its balanced presentation of theory, methods, and applications and its highly readable style, A First Course in the Design of Experiments proves ideal as a text for a beginning graduate or upper-level undergraduate course in the design and analysis of experiments.