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Author: John H. Evans Publisher: Oxford University Press ISBN: 0197519571 Category : Science Languages : en Pages : 288
Book Description
In 2018 the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the pre-existing moral consensus, which had held for over fifty years before: while gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. If this line is passed over, scientists will be left without an agreed-upon ethical limit. What do we do now? John H. Evans here provides a meta-level guide to how these debates move forward and their significance to society. He explains how the bioethical debate has long been characterized as a slippery slope, with consensually ethical use at the top, nightmarish dystopia at the bottom, and specific agreed-upon limits in between, which draw the lines between the ethical and the unethical. Evans frames his analysis around these limits, or barriers. Historically they have existed to guide scientists and to prevent the debate from slipping down the metaphorical slope into unacceptable eugenicist possibilities, such as in Aldous Huxley's novel Brave New World or the movie Gattaca. Evans examines the history of how barriers were placed, then fell, then replaced by new ones, and discusses how these insights inform where the debate may head. He evaluates other proposed barriers relevant to where we are now, projects that most of the barriers suggested by scientists and bioethicists will not hold, and cautiously identifies a few that could serve as the moral boundary for the next generation. At a critical time in this new era of intervention in the human genome, The Human Gene Editing Debate provides a necessary, comprehensive analysis of the conversation's direction, past, present, and future.
Author: John H. Evans Publisher: Oxford University Press ISBN: 0197519571 Category : Science Languages : en Pages : 288
Book Description
In 2018 the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the pre-existing moral consensus, which had held for over fifty years before: while gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. If this line is passed over, scientists will be left without an agreed-upon ethical limit. What do we do now? John H. Evans here provides a meta-level guide to how these debates move forward and their significance to society. He explains how the bioethical debate has long been characterized as a slippery slope, with consensually ethical use at the top, nightmarish dystopia at the bottom, and specific agreed-upon limits in between, which draw the lines between the ethical and the unethical. Evans frames his analysis around these limits, or barriers. Historically they have existed to guide scientists and to prevent the debate from slipping down the metaphorical slope into unacceptable eugenicist possibilities, such as in Aldous Huxley's novel Brave New World or the movie Gattaca. Evans examines the history of how barriers were placed, then fell, then replaced by new ones, and discusses how these insights inform where the debate may head. He evaluates other proposed barriers relevant to where we are now, projects that most of the barriers suggested by scientists and bioethicists will not hold, and cautiously identifies a few that could serve as the moral boundary for the next generation. At a critical time in this new era of intervention in the human genome, The Human Gene Editing Debate provides a necessary, comprehensive analysis of the conversation's direction, past, present, and future.
Author: Celeste Michelle Condit Publisher: Univ of Wisconsin Press ISBN: 9780299163648 Category : Language Arts & Disciplines Languages : en Pages : 348
Book Description
The Meanings of the Gene is a compelling look at societal hopes and fears about genetics in the course of the twentieth century. The work of scientists and doctors in advancing genetic research and its applications has been accompanied by plenty of discussion in the popular press—from Good Housekeeping and Forbes to Ms. and the Congressional Record—about such topics as eugenics, sterilization, DNA, genetic counseling, and sex selection. By demonstrating the role of rhetoric and ideology in public discussions about genetics, Condit raises the controversial question, Who shapes decisions about genetic research and its consequences for humans—scientists, or the public? Analyzing hundreds of stories from American magazines—and, later, television news—from the 1910s to the 1990s, Condit identifies three central and enduring public worries about genetics: that genes are deterministic arbiters of human fate; that genetics research can be used for discriminatory ends; and that advances in genetics encourage perfectionistic thinking about our children. Other key public concerns that Condit highlights are the complexity of genetic decision-making and potential for invasion of privacy; conflict over the human genetic code and experimentation with DNA; and family genetics and reproductive decisions. Her analysis reveals a persistent debate in the popular media between themes of genetic determinism (such as eugenics) and more egalitarian views that place genes within the complexity of biological and social life. The Meanings of the Gene offers an insightful view of our continuing efforts to grapple with our biological natures and to define what it means, and will mean in the future, to be human.
Author: Alexandra Plows Publisher: Routledge ISBN: 1134057857 Category : Medical Languages : en Pages : 481
Book Description
Debating Human Genetics is based on ethnographic research focusing primarily on the UK publics who are debating and engaging with human genetics, and related bio and techno-science. Drawing on recent interviews and data, collated in a range of public settings, it provides a unique overview of multiple publics as they ‘frame’ the stake of the debates in this emerging, complex and controversial arena. The book outlines key sites and applications of human genetics that have sparked public interest, such as biobanks, stem cells, genetic screening and genomics. It also addresses the ‘scientific contoversies’ that have made considerable impact in the public sphere – the UK police DNA database, gene patenting, ‘saviour siblings’, and human cloning. By grounding the concepts and issues of human genetics in the real life narratives and actions of patient groups, genetic watchdogs, scientists, policy makers, and many other public groups, the book exemplifies how human genetics is a site where public knowledge and value claims converge and collide, and identifies the emergence of ‘hybrid publics’ who are engaging with this hybrid science.
Author: Glenn McGee Publisher: ISBN: Category : Health & Fitness Languages : en Pages : 340
Book Description
Since Scottish biologist Ian Wilmut's 1997 cloning of Dolly the sheep, mice, cattle, goats, pigs, cats, mules, horses, and most recently, rats have joined the list of cloned animals, pushing the possibilities for scientific manipulation of life to new extremes. The first book to present Wilmut's own thoughts on the troubling ramifications of this technology, this new edition also contains discussions about the advantages and disadvantages of cloning, stem cell research, and a survey of religious perspectives.
Author: National Research Council Publisher: National Academies Press ISBN: 0309184746 Category : Science Languages : en Pages : 101
Book Description
This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.
Author: Gisela T. Kaplan Publisher: Other Press, LLC ISBN: 9781590510346 Category : Medical Languages : en Pages : 312
Book Description
The authors criticise the new, genetic explanations for human behaviour. They describe the theory of biology, and the reality in which a gendered world and the women's biology and the consequences are described. In the chapter 'Perpetuity' they discuss the gay and queer gene.
Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309452880 Category : Medical Languages : en Pages : 329
Book Description
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Author: Matt Ridley Publisher: Harper Collins ISBN: 0060006781 Category : Psychology Languages : en Pages : 340
Book Description
Following his highly praised and bestselling book Genome: The Autobiography of a Species in 23 Chapters, Matt Ridley has written a brilliant and profound book about the roots of human behavior. Nature via Nurture explores the complex and endlessly intriguing question of what makes us who we are. In February 2001 it was announced that the human genome contains not 100,000 genes, as originally postulated, but only 30,000. This startling revision led some scientists to conclude that there are simply not enough human genes to account for all the different ways people behave: we must be made by nurture, not nature. Yet again biology was to be stretched on the Procrustean bed of the nature-nurture debate. Matt Ridley argues that the emerging truth is far more interesting than this myth. Nurture depends on genes, too, and genes need nurture. Genes not only predetermine the broad structure of the brain, they also absorb formative experiences, react to social cues, and even run memory. They are consequences as well as causes of the will. Published fifty years after the discovery of the double helix of DNA, Nature via Nurture chronicles a revolution in our understanding of genes. Ridley recounts the hundred years' war between the partisans of nature and nurture to explain how this paradoxical creature, the human being, can be simultaneously free-willed and motivated by instinct and culture. Nature via Nurture is an enthralling,up-to-the-minute account of how genes build brains to absorb experience.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309133815 Category : Social Science Languages : en Pages : 384
Book Description
Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.
Author: John H. Evans
Author: John H. Evans
Author: John H. Evans
Author: Celeste Michelle Condit
Author: Alexandra Plows
Author: Glenn McGee
Author: National Research Council
Author: Gisela T. Kaplan
Author: National Academies of Sciences, Engineering, and Medicine
Author: Matt Ridley
Author: Institute of Medicine