Author: Mahin D. MainesPublisher: Current Protocols
ISBN: 9780471266754
Category :
Languages : en
Pages :
Book Description
Current Protocols in Toxicology Late Subscriber Or Der
Author: Mahin D. MainesPublisher: Current Protocols
ISBN: 9780471266754
Category :
Languages : en
Pages :
Book Description
Current Protocols in Pharmacology Late Subscriber Order
Author: EnnaPublisher: Current Protocols
ISBN: 9780471266747
Category :
Languages : en
Pages :
Book Description
Current Protocols in Toxicology
Author: e.aCurrent Protocols in Toxicology
Author: Current Protocols in Toxicology Core Reprint
Author: MainesCurrent Protocols in Toxicology Online
Author: Mahin D. MainesPublisher: Current Protocols
ISBN: 9780471140856
Category :
Languages : en
Pages :
Book Description
Toxicological research is driven by the need to understand and assess the human and ecological risks of exposure to chemicals and other toxicants as well as by interest in using toxic agents to elucidate basic biological and pathobiological processes. The level of research activity in this field is higher, the rate of change in knowledge more rapid, and interest in applying scientific information to societally important issues is greater than ever before. These are exciting and challenging times to be working in toxicology. The ongoing ferment builds on the extraordinary advances being made in the understanding of biological systems at the molecular level. This fundamental knowledge provides the opportunity for greatly enhanced insight into how chemicals and other stressors may damage biological structures and processes, influence the rate of biological repair, and lead to reversible or irreversible diseases or to a return to health. Society increasingly calls on the scientific community for the knowledge needed both to reevaluate the health hazards of existing products and technologies and to evaluate the prospective hazards of new ones. Such information is used to develop guidelines and regulations designed to ensure that these new products and technologies do not harm people or the environment. Acquiring sound, reproducible scientific data that can be integrated with existing information to advance the knowledge of toxicants and living systems requires rigorous adherence to the scientific method. This means intelligent, thoughtful individuals identifying important needs, formulating testable hypotheses, designing experiments to test them, meticulously conducting these experiments, carefully reviewing and interpreting it in the peer-reviewed literature. Current Protocols in Toxicology is a clear and well-documented compendium of the most important methods in the field?proven approaches developed by leading researchers?for the benefit of other experimentalists, from students to seasoned investigators. Since toxicology by its nature is multidisciplinary, other titles in the Current Protocols series may also provide relevant methods. Although review of the literature cited for each procedure can give added insight into the underlying theory and breadth of applications, the protocols have been carefully designed to provide clear, step-by-step descriptions that can easily be followed even by the relatively inexperienced.Regular updates to Current Protocols in Toxicology manual will help ensure an awareness of changes in previously documented methods and of methods newly developed. Use of these protocols will avoid unnecessary duplication of effort in development and validation when the methods are applied without modification, and will speed up the development of more refined methods that will further advance the field of toxicology and, in turn, may have a place in future updates.Roger O. McClellanChemical Industry of ToxicologyResearch Triangle Park, North Carolina
Current Protocols in Toxicology on CD-ROM
Author: MainesCurrent Protocols in Toxicology Supplement 21
Author: MainesCurrent Protocols in Neuroscience
Author: Jacqueline N. CrawleyPublisher: Current Protocols
ISBN: 9780471163619
Category : Medical
Languages : en
Pages :
Book Description
Current Protocols in Neuroscience (CPN) draws from techniques in molecular neurobiology, neurophysiology, neuroanatomy, neuropharmacology, and behavioral neuroscience to meet the specific needs of researchers in the full range of disciplines that is involved in studying the brain, nervous system, and corresponding behaviors. The editorial board of CPN have assembled an outstanding range of methods to enable users to explore their fields in greater depth and branch into related areas. The one-volume, looseleaf manual features carefully edited techniques with authors' troubleshooting tips and helpful comments that come from extensive experience in using these procedures. Quarterly updates, filed into the looseleaf, keep you and your laboratory current with the latest developments in this rapidly changing field. The initial purchase includes one year of updates and then subscribers may renew their annual subscriptions. Current Protocols publishes a family of laboratory manuals for bioscientists, including Molecular Biology, Immunology, Human Genetics, Protein Science, Cytometry, Cell Biology, Pharmacology, and Toxicology.
Predictive Toxicology in Drug Safety
Author: Jinghai J. XuPublisher: Cambridge University Press
ISBN: 1139493094
Category : Medical
Languages : en
Pages :
Book Description
According to the Institute of Medicine (IOM) and U.S. Food and Drug Administration (FDA), 'developing new scientific approaches to detecting, understanding, predicting and preventing adverse events' was a critical path to the future of drug safety. This book brings together a collection of state-of-the-art chapters, written by experts in the drug safety field. It provides information on the present knowledge of drug side effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology. Each specific area of toxicology relevant for drug discovery is discussed in detail, including theory, experimental approaches and data interpretation supported by comprehensive up-to-date references. Many chapters provide fascinating case studies, which are of general interest for those who have basic science training and are interested in how chemicals interact with the human body.