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Author: David Healy Publisher: Harvard University Press ISBN: 9780674038455 Category : Medical Languages : en Pages : 484
Book Description
David Healy follows his widely praised study, The Antidepressant Era, with an even more ambitious and dramatic story: the discovery and development of antipsychotic medication. Healy argues that the discovery of chlorpromazine (more generally known as Thorazine) is as significant in the history of medicine as the discovery of penicillin, reminding readers of the worldwide prevalence of insanity within living memory. But Healy tells not of the triumph of science but of a stream of fruitful accidents, of technological discovery leading neuroscientific research, of fierce professional competition and the backlash of the antipsychiatry movement of the 1960s. A chemical treatment was developed for one purpose, and as long as some theoretical rationale could be found, doctors administered it to the insane patients in their care to see if it would help. Sometimes it did, dramatically. Why these treatments worked, Healy argues provocatively, was, and often still is, a mystery. Nonetheless, such discoveries made and unmade academic reputations and inspired intense politicking for the Nobel Prize. Once pharmaceutical companies recognized the commercial potential of antipsychotic medications, financial as well as clinical pressures drove the development of ever more aggressively marketed medications. With verve and immense learning, Healy tells a story with surprising implications in a book that will become the leading scholarly work on its compelling subject.
Author: David Healy Publisher: Harvard University Press ISBN: 9780674038455 Category : Medical Languages : en Pages : 484
Book Description
David Healy follows his widely praised study, The Antidepressant Era, with an even more ambitious and dramatic story: the discovery and development of antipsychotic medication. Healy argues that the discovery of chlorpromazine (more generally known as Thorazine) is as significant in the history of medicine as the discovery of penicillin, reminding readers of the worldwide prevalence of insanity within living memory. But Healy tells not of the triumph of science but of a stream of fruitful accidents, of technological discovery leading neuroscientific research, of fierce professional competition and the backlash of the antipsychiatry movement of the 1960s. A chemical treatment was developed for one purpose, and as long as some theoretical rationale could be found, doctors administered it to the insane patients in their care to see if it would help. Sometimes it did, dramatically. Why these treatments worked, Healy argues provocatively, was, and often still is, a mystery. Nonetheless, such discoveries made and unmade academic reputations and inspired intense politicking for the Nobel Prize. Once pharmaceutical companies recognized the commercial potential of antipsychotic medications, financial as well as clinical pressures drove the development of ever more aggressively marketed medications. With verve and immense learning, Healy tells a story with surprising implications in a book that will become the leading scholarly work on its compelling subject.
Author: Peter M. Haddad Publisher: ISBN: 9781911623465 Category : Languages : en Pages :
Book Description
"The 2nd edition of this book was edited by David King and published in 2004. Since then there have been major advances in psychopharmacology in terms of new medications coming to the market, increased understanding of the mechanisms of drug action and new data on the efficacy, tolerability, safety and clinical effectiveness of a range of medications. Partly as a result, clinical guidelines for many psychiatric disorders have altered. As such, a new edition of this textbook was essential and we were delighted when the College approached us to edit the 3rd edition. This was a major endeavor that was only possible with the commitment and expertise of the authors"--
Author: S. Nassir Ghaemi Publisher: Oxford University Press ISBN: 0199995508 Category : Medical Languages : en Pages : 601
Book Description
Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores two major aspects of the field: the clinical research that exists to guide clinical practice of psychopharmacology, and the application of that knowledge with attention to the individualized aspects of clinical practice. The text consists of 50 chapters, organized into 6 sections, focusing on disease-modifying effects, non-DSM diagnostic concepts, and essential facts about the most common drugs. This innovative book advocates a scientific and humanistic approach to practice and examines not only the benefits, but also the harms of drugs. Providing a solid foundation of knowledge and a great deal of practical information, this book is a valuable resource for practicing psychiatrists, psychiatric nurse practitioners, medical students and trainees in psychiatry, as well as pharmacists.
Author: Rudy Schreiber Publisher: Springer Nature ISBN: 3030623513 Category : Medical Languages : en Pages : 285
Book Description
This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.
Author: Joseph F. Goldberg Publisher: Cambridge University Press ISBN: 1108450741 Category : Medical Languages : en Pages : 611
Book Description
A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments.
Author: David Osser Publisher: Lippincott Williams & Wilkins ISBN: 1975151216 Category : Medical Languages : en Pages : 384
Book Description
Algorithms serve an important purpose in the field of psychopharmacology as heuristics for avoiding the biases and cognitive lapses that are common when prescribing for many conditions whose treatment is based on complex data. Unique in the field, this title compiles twelve papers from the Psychopharmacology Algorithm Project at the Harvard South Shore Psychiatry Residency Training Program and presents practical ways to adopt evidence-based practices into the day-to-day treatment of patients. Psychopharmacology Algorithms is a useful resource for practicing psychiatrists, residents, and fellows, as well as psychiatric nurse practitioners, psychiatric physician assistants who prescribe, advanced practice pharmacists who prescribe, and primary care clinicians. Teachers of psychopharmacology may find it particularly valuable. Researchers in clinical psychopharmacology may find it helpful in identifying important practice areas that are in need of further study.
Author: Sharon L. Crowell-Davis Publisher: John Wiley & Sons ISBN: 0470344148 Category : Medical Languages : en Pages : 288
Book Description
Every day veterinarians in practice are asked to treat petsexhibiting problem behaviors. In the last several yearspharmacologic treatments of behavior have made significant advancesand can serve as a critical part of therapy. Veterinary Pscyhopharmacology is a complete source of currentknowledge on the subject of pharmacologic behavior modificationthat veterinarians can turn to for the answers they need. Classification of disorders is eschewed in favor of in-depthexplanations of pharmacologic options in inducing behavior changes.Special emphasis is given to explaining the underlying mechanism ofpharmacologic agents used in therapy; thus, veterinarians will knownot only which drugs to prescribe but why they should be prescribedand how they work. Veterinary behaviorists, their students and residents, veterinarypractitioners of all levels, and veterinary students will find thisbook invaluable in providing information about their patients'behavior problems and the psychoactive medications that might helpthem.
Author: Michael A. Reveley Publisher: CRC Press ISBN: 9780340759127 Category : Medical Languages : en Pages : 288
Book Description
This unique and timely book examines the basic and clinical sciences relevant to schizophrenia and relates them to current treatment strategies. Through describing current thinking on the aetiology and pathophysiology of schizophrenia as relevant to the psychopharmacology of the disorder, the reader gains a fuller understanding of the rationale for psychopharmacological approaches to treatment. Neuroimaging and neuropsychology are covered in detail as well as further chapters on clinical strategies for treatment of schizophrenia with both conventional and atypical antipsychotic treatments. Practical advice on the management of schizophrenia in the community is also given. Bringing together new developments and advances in the field, while discussing important issues relevant to the long-term treatment necessary for this disorder, the result is an essential book for psychiatrists and psychopharmacologists at all levels.
Author: Ian M. Anderson Publisher: CRC Press ISBN: 9780203448304 Category : Medical Languages : en Pages : 172
Book Description
In the rapidly changing field of pharmacology, it is essential that all those involved in the prescribing or administering of medication to people with mental disorders keep up to date with the latest developments. This book is based on the highly successful course for trainee psychiatrists held twice yearly in Great Britain. Leading psychiatrists
Author: Kenneth L. Davis Publisher: Lippincott Williams & Wilkins ISBN: 9780781728379 Category : Medical Languages : en Pages : 1964
Book Description
Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Author: David Healy
Author: David Healy
Author: Peter M. Haddad
Author: S. Nassir Ghaemi
Author: Rudy Schreiber
Author: Joseph F. Goldberg
Author: David Osser
Author: Sharon L. Crowell-Davis
Author: Michael A. Reveley
Author: Ian M. Anderson
Author: Kenneth L. Davis