Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Cooperativity Theory in Biochemistry PDF full book. Access full book title Cooperativity Theory in Biochemistry by T.L. Hill. Download full books in PDF and EPUB format.
Author: T.L. Hill Publisher: Springer Science & Business Media ISBN: 146125082X Category : Science Languages : en Pages : 468
Book Description
During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was trans mitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects of life at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for rep licating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macromolecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living sys tems. It might be said that these few decades have replaced a near vacuum of information with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective-what is known about the field today-and a description of the frontiers of research where our knowledge is increasing steadily.
Author: T.L. Hill Publisher: Springer Science & Business Media ISBN: 146125082X Category : Science Languages : en Pages : 468
Book Description
During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was trans mitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects of life at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for rep licating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macromolecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living sys tems. It might be said that these few decades have replaced a near vacuum of information with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective-what is known about the field today-and a description of the frontiers of research where our knowledge is increasing steadily.
Author: Arieh Ben-Naim Publisher: Springer Science & Business Media ISBN: 9780306463310 Category : Medical Languages : en Pages : 366
Book Description
This is the first book that attempts to study the origin of cooperatvity in binding systems from the molecular point of view. The molecular approach provides a deeper insight into the mechanism of cooperativity and regulation, than the traditional phenomenological approach. This book uses the tools of statistical mechanics to present the molecular theory of cooperativity. Cooperativity is used in a variety of processes-such as loading and unloading of oxygen at relatively small pressure differences; maintaining an almost constant concentration of various compounds in living cells; and switching on and off the reading of genetic information. This book may be used as a textbook by graduate students in Chemistry, Biochemistry and Biophysics, and will also be of interest to researchers in theoretical biochemistry.
Author: Arieh Y. Ben-Naim Publisher: Springer Science & Business Media ISBN: 147573302X Category : Science Languages : en Pages : 358
Book Description
This is the first book that attempts to study the origin of cooperatvity in binding systems from the molecular point of view. The molecular approach provides a deeper insight into the mechanism of cooperativity and regulation, than the traditional phenomenological approach. This book uses the tools of statistical mechanics to present the molecular theory of cooperativity. Cooperativity is used in a variety of processes-such as loading and unloading of oxygen at relatively small pressure differences; maintaining an almost constant concentration of various compounds in living cells; and switching on and off the reading of genetic information. This book may be used as a textbook by graduate students in Chemistry, Biochemistry and Biophysics, and will also be of interest to researchers in theoretical biochemistry.
Author: Jo M. Holt Publisher: Elsevier ISBN: 0080497179 Category : Science Languages : en Pages : 315
Book Description
This volume focuses on the cooperative binding aspects of energetics in biological macromolecules. Methodologies such as NMR, small-angle scattering techniques for analysis, calorimetric analysis, fluorescence quenching, and time resolved FRET measurements are discussed.*Methods for Evaluating Cooperativity in a Dimeric Hemoglobin*Multiple-Binding of Ligands to a Linear Biopolymer*Fluorescence Quenching Methods to Study Protein-Nucleic Acid Interactions*Linked Equilibria in Biotin Repressor Function: Thermodynamic, Structural and Kinetic Analysis
Author: Bernard L. Horecker Publisher: Elsevier ISBN: 1483217280 Category : Technology & Engineering Languages : en Pages : 365
Book Description
Current Topics in Cellular Regulation: Volume 29 is a collection of papers that deals with dynamic macromolecular interactions, ligand binding, multi-enzyme complex formation, the regulation of fatty acid uptake, and synthesis in mammary or adipose tissues. Other papers explain the functional relationships of guanosine triphosphate binding proteins, the glycogen storage disease, the regulation of the pentose phosphate pathway in the brain, as well as the regulation of carotenoid biosynthesis. One paper discusses the dissociable enzyme complexes stabilized by weak interactions, particularly on the interaction of cytosolic enzymes with the contractile apparatus, with membranes, or with functionally related enzymes. Another paper investigates the mechanism of acute regulation, in mammary epithelial cells, of the processes which collaborate to supply fatty acids for esterification to form glycerolipids (which is predominantly triacylglycerol). Glycerolipids comprise mostly the total lipid content of the secretory product of those cells—mammalian milk. The paper notes that a counter-regulatory hormone collaborating with insulin in the regulation of lipid metabolism in the lactating mammary cell, does not act via cyclic AMP. The collection can prove beneficial for biochemists, micro-biologists, bio-physicists, cellular researchers, and academicians involved in the study of cellular biology or physiology.
Author: Arieh Y. Ben-Naim Publisher: Springer Science & Business Media ISBN: 1475715986 Category : Science Languages : en Pages : 700
Book Description
This book was planned and written with one central goal in mind: to demonstrate that statistical thermodynamics can be used successfully by a broad group of scientists, ranging from chemists through biochemists to biologists, who are not and do not intend to become specialists in statistical thermodynamics. The book is addressed mainly to gradu ate students and research scientists interested in designing experiments the results of which may be interpreted at the molecular level, or in interpreting such experimental results. It is not addressed to those who intend to practice statistical thermodynamics per se. With this goal in mind, I have expended a great deal of effort to make the book clear, readable, and, I hope, enjoyable. This does not necessarily mean that the book as a whole is easy to read. The first four chapters are very detailed. The last four become progressively more difficult to read, for several reasons. First, presuming that the reader has already acquired familiarity with the methods and arguments presented in the first part, I felt that similar arguments could be skipped later on, leaving the details to be filled in by the reader. Second, the systems themselves become progressively more com plicated as we proceed toward the last chapter.
Author: T.L. Hill
Author: T.L. Hill
Author: Arieh Ben-Naim
Author: Terrell L. Hill
Author: Arieh Y. Ben-Naim
Author: Max F. Perutz
Author: Jo M. Holt
Author: National Library of Medicine (U.S.)
Author: National Library of Medicine (U.S.)
Author: Bernard L. Horecker
Author: Arieh Y. Ben-Naim