Author: Pierre LemarchalPublisher:
ISBN:
Category :
Languages : fr
Pages :
Book Description
Contribution à l'étude de la dynamique conformationnelle des macromolécules en solution
Author: Pierre LemarchalContribution à l'étude de la dynamique conformationnelle des macromolécules en solution par spectrométrie ultrasonore
Author: Pierre LemarechalContribution à l'étude de la polydispersioné des solutions macromoléculaires
Author: Michel DauneContribution à l'étude de la polydispersité des solution macromoléculaires
Author: Michel DauneContribution à l'étude de la polydispersité des solutions macromoléculaires
Author: Michel DauneSingle-particle Cryo-electron Microscopy
Author: Joachim FrankPublisher: World Scientific Publishing Company
ISBN: 9789813234857
Category : Electron microscopy
Languages : en
Pages : 0
Book Description
The book reproduces 55 of more than 300 articles written by the author, representing milestones in methods development of single-particle cryo-EM as well as important results obtained by this technique in the study of biological macromolecules and their interactions. Importantly, neither symmetries nor ordered arrangements (as in two-dimensional crystals, helical assemblies, icosahedral viruses) are required. Although the biological applications are mainly in the area of ribosome structure and function, the elucidation of membrane channel structures and their activation and gating mechanisms are represented, as well. The book is introduced by a commentary that explains the original development of concepts, describes the contributions of the author's colleagues and students, and shows how challenges were overcome as the technique matured. Along the way, the ribosome served as an example for a macromolecule with intricate structure and conformational dynamics that pose challenges for three-dimensional visualization. Toward the end of the book -- bringing us to the present time -- molecular structures with near-atomic resolution are presented, and a novel type of computational analysis, manifold embedding, is introduced. Single-particle cryo-EM is currently revolutionizing structural biology, presenting a powerful alternative to X-ray crystallography as a means to solve the structure of biological macromolecules. The book presents in one place a number of articles containing key advances in mathematical and computational methods leading up to the present time. Secondly, the development of the technique over the years is reflected by ever-expanding discoveries in the field of ribosome structure and function. Thirdly, as all histories of ideas, the history of concepts pertaining to this new method of visualization is fascinating all in itself.
Analusis
Author: Publisher:
ISBN:
Category : Analytical chemistry
Languages : en
Pages : 1098
Book Description
Coherent Excitations in Biological Systems
Author: H. FröhlichPublisher: Springer Science & Business Media
ISBN: 3642691862
Category : Medical
Languages : en
Pages : 234
Book Description
The articles in this volume are based on papers presented at the International Symposium in Bad Neuenahr November 29 - December 1, 1982. The meeting was directed by H. Frohlich and was sponsored by IBM Deutschland through its Science and Education Programs Department. Contents Coherence in Biology H. Frohlich . Coherent Excitations and Raman Effect F. Drissler and L. Santo (With 4 Figures) 6 The Non-thermal Effect of Millimeter Wave Radiation on the Puffing of Giant Chromosomes F. Kremer, C. Koschnitzke, L. Santo, P. Quick, and A. Poglitsch (With 4 Figures) 10 Nonthermal Resonant Effects of 42 GHz Microwaves on the Growth of Yeast Cultures W. Grundler, F. Keilmann, V. Putterlik, L. Santo, D. Strube, and I. Zimmermann (With 15 Figures) 21 On the Microwave Response of the Drosophila Melanogaster G. Nimtz (With 5 Figures) 38 Effects of Low-level Millimeter Waves on Cellular and Subcellular Systems S. M. Motzkin, L. Benes, N. Block, B. Israel, N. May, J. Kuriyel, L. Birenbaum, S. Rosenthal, and Q. Han (With 12 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Millimeter-wave and Far-infrared Spec roscopy on Biological Macromolecules L. Genzel, F. Kremer, A. Poglitsch, and G. Bechtold (With 10 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Excitation of Proteins by Electric Fields J. B. Hasted, S. K. Husain, A. Y. Ko, D. Rosen, E. Nicol, and J. R. Birch (With 8 Figures) 71 Isotope Effects and Collective Excitations M. U. Palma (With 3 Figures) 84 Long-range Energy Continua in the Living Cell: Protochemical Considerations G. R. Welch and M. N. Berry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Comprehensive Foodomics
Author: Publisher: Elsevier
ISBN: 0128163968
Category : Science
Languages : en
Pages : 2444
Book Description
Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,’ comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe
Nonlinear Electrodynamics in Biological Systems
Author: W. AdeyPublisher: Springer Science & Business Media
ISBN: 146132789X
Category : Science
Languages : en
Pages : 589
Book Description
The past half century has seen an extraordinary growth in the fields of cellular and molecular biology. From simple morphologi cal concepts of cells as the essential units of living matter there has been an ever-sharper focus on functional organization of living systems, with emphasis on molecular dynamics. Thus, life forms have come to be defined increasingly in terms of metabolism, growth, reproduction and responses to environmental perturbations. Since these properties occur in varying degrees in systems below the level of cellular organization, there has been a blurring of older models that restricted the concepts of life to cellular systems. At the same time, a search has begun for elemental as pects of molecular and atomic behavior that might better define properties common to all life forms. This search has led to an examination of nonlinear behavior in biological macromolecules, whether in response to electrical or chemical stimulation, for example, or as a means of signaling along a molecular chain, or as a means of energy transfer. Experimental knowledge in this area has grown rapidly in the past decade, and in some respects has outstripped theoretical models adequate to ex plain these new observations. Nevertheless, it can be claimed that there is now an impressive body of experiments implicating non linear, nonequilibrium processes as fundamental steps in sequential operations of biological systems.