The Life Sciences PDF Download

Author:
Publisher: National Academies
ISBN:
Category : Science
Languages : en
Pages : 552

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Author: William Siler
Publisher: Springer Science & Business Media
ISBN: 1475705468
Category : Science
Languages : en
Pages : 250

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Book Description
45 certainty about Federal policy concern the University of Alabama cardiac in ing the support of training contribute tensive care monitoring system on "ob to these difficulties. The problems are solete 1800 computers." Another re too broad and too complex to address sponded most efficaciously pointing out here. They are difficult for both aca that it is too bad that people lose sight of demia and government, and warrant the fact that a system on which a pro the active concern of the entire research gram is developed will always be able community. to do the job; change is not indicated Dr. Robert Macey introduced to the until the system ceases to be appropri ate. conference the exciting world of model development describing an application In another vein, the question opens to the area of membrane transport. The up a wide range of problems that can be discussion of his paper exposed the prob summarized as problems in the diffusion lern the modeler has of gaining ac of computer-based technology. At this ceptance of his particular approach, but juncture biomedical computing joins all mainly it provided a taste of the intellec the rest of biomedicine. The problems of tual excitement that modeling generates diffusion of advances in health research, among both doers and observers.

Author: Joseph A. November
Publisher: JHU Press
ISBN: 1421406659
Category : Technology & Engineering
Languages : en
Pages : 361

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Book Description
Winner of the Computer History Museum Prize of the Special Interest Group: Computers, Information, and Society Imagine biology and medicine today without computers. What would laboratory work be like if electronic databases and statistical software did not exist? Would disciplines like genomics even be feasible if we lacked the means to manage and manipulate huge volumes of digital data? How would patients fare in a world absent CT scans, programmable pacemakers, and computerized medical records? Today, computers are a critical component of almost all research in biology and medicine. Yet, just fifty years ago, the study of life was by far the least digitized field of science, its living subject matter thought too complex and dynamic to be meaningfully analyzed by logic-driven computers. In this long-overdue study, historian Joseph November explores the early attempts, in the 1950s and 1960s, to computerize biomedical research in the United States. Computers and biomedical research are now so intimately connected that it is difficult to imagine when such critical work was offline. Biomedical Computing transports readers back to such a time and investigates how computers first appeared in the research lab and doctor's office. November examines the conditions that made possible the computerization of biology—including strong technological, institutional, and political support from the National Institutes of Health—and shows not only how digital technology transformed the life sciences but also how the intersection of the two led to important developments in computer architecture and software design. The history of this phenomenon has been only vaguely understood. November's thoroughly researched and lively study makes clear for readers the motives behind computerizing the study of life and how that technology profoundly affects biomedical research today.

Author: National Research Council
Publisher: National Academies Press
ISBN: 030909612X
Category : Science
Languages : en
Pages : 469

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Book Description
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.

Author: Kyle Kirkland
Publisher: Infobase Publishing
ISBN: 0816074410
Category : Computer science
Languages : en
Pages : 225

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Investigates the research and discoveries of computer scientists whose efforts have expanded knowledge of the rapidly changing field of computer science.

Author: Rafael A. Irizarry
Publisher: CRC Press
ISBN: 1498775861
Category : Mathematics
Languages : en
Pages : 537

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Book Description
This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

Author: Bernard A. Megrey
Publisher: Springer Science & Business Media
ISBN: 1402086369
Category : Science
Languages : en
Pages : 427

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The first edition of this book was published by Chapman and Hall Ltd. in 1996. The first edition contained nine chapters and, for all except one chapter, the original chapter authors agreed to update their chapter. Comparing these chapters gives the reader an idea of the development over a time span of more than 10 years between the two editions. In the preparation of the second edition we decided to add more chapters reflecting some important fields with significant contributions to present day fishery research. These are the use of internet for searching of information (Chapter 2), and the present state and use of remote sensing (Chapter 5), ecosystem modeling (Chapter 8) and visualization of data (Chapter 10). This second edition provides a valuable sampling of contemporary applications. Scientists have an opportunity to evaluate the suitability of different computer technology applications to their particular research situation thereby taking advantage of the experience of others. The chapters that follow are the fruition of this idea. The history behind this book started in 1989 when we were asked by Dr. Vidar Wespestad (previously: Alaska Fisheries Science Center, Seattle, USA) to prepare and convene a session at the 1992 World Fishery Congress in Athens, Greece on computer applications in fisheries. We agreed that the idea was a good one and the computer session in 1992 turned out to be very successful.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458889
Category : Science
Languages : en
Pages : 115

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Book Description
The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.

Author: Alexander Lancaster
Publisher: Apress
ISBN: 1484245237
Category : Computers
Languages : en
Pages : 396

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Book Description
Treat yourself to a lively, intuitive, and easy-to-follow introduction to computer programming in Python. The book was written specifically for biologists with little or no prior experience of writing code - with the goal of giving them not only a foundation in Python programming, but also the confidence and inspiration to start using Python in their own research. Virtually all of the examples in the book are drawn from across a wide spectrum of life science research, from simple biochemical calculations and sequence analysis, to modeling the dynamic interactions of genes and proteins in cells, or the drift of genes in an evolving population. Best of all, Python for the Life Sciences shows you how to implement all of these projects in Python, one of the most popular programming languages for scientific computing. If you are a life scientist interested in learning Python to jump-start your research, this is the book for you. What You'll Learn Write Python scripts to automate your lab calculations Search for important motifs in genome sequences Use object-oriented programming with Python Study mining interaction network data for patterns Review dynamic modeling of biochemical switches Who This Book Is For Life scientists with little or no programming experience, including undergraduate and graduate students, postdoctoral researchers in academia and industry, medical professionals, and teachers/lecturers. “A comprehensive introduction to using Python for computational biology... A lovely book with humor and perspective” -- John Novembre, Associate Professor of Human Genetics, University of Chicago and MacArthur Fellow “Fun, entertaining, witty and darn useful. A magical portal to the big data revolution” -- Sandro Santagata, Assistant Professor in Pathology, Harvard Medical School “Alex and Gordon’s enthusiasm for Python is contagious” -- Glenys Thomson Professor of Integrative Biology, University of California, Berkeley

Author: David Riaño
Publisher: Springer
ISBN: 303021642X
Category : Computers
Languages : en
Pages : 431

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Book Description
This book constitutes the refereed proceedings of the 17th Conference on Artificial Intelligence in Medicine, AIME 2019, held in Poznan, Poland, in June 2019. The 22 revised full and 31 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: deep learning; simulation; knowledge representation; probabilistic models; behavior monitoring; clustering, natural language processing, and decision support; feature selection; image processing; general machine learning; and unsupervised learning.