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Author: Maurizio De Pittà Publisher: Springer ISBN: 3030008177 Category : Medical Languages : en Pages : 505
Book Description
Over the last two decades, the recognition that astrocytes - the predominant type of cortical glial cells - could sense neighboring neuronal activity and release neuroactive agents, has been instrumental in the uncovering of many roles that these cells could play in brain processing and the storage of information. These findings initiated a conceptual revolution that leads to rethinking how brain communication works since they imply that information travels and is processed not just in the neuronal circuitry but in an expanded neuron-glial network. On the other hand the physiological need for astrocyte signaling in brain information processing and the modes of action of these cells in computational tasks remain largely undefined. This is due, to a large extent, both to the lack of conclusive experimental evidence, and to a substantial lack of a theoretical framework to address modeling and characterization of the many possible astrocyte functions. This book that we propose aims at filling this gap, providing the first systematic computational approach to the complex, wide subject of neuron-glia interactions. The organization of the book is unique insofar as it considers a selection of “hot topics” in glia research that ideally brings together both the novelty of the recent experimental findings in the field and the modelling challenge that they bear. A chapter written by experimentalists, possibly in collaboration with theoreticians, will introduce each topic. The aim of this chapter, that we foresee less technical in its style than in conventional reviews, will be to provide a review as clear as possible, of what is “established” and what remains speculative (i.e. the open questions). Each topic will then be presented in its possible different aspects, by 2-3 chapters by theoreticians. These chapters will be edited in order to provide a “priming” reference for modeling neuron-glia interactions, suitable both for the graduate student and the professional researcher.
Author: Maurizio De Pittà Publisher: Springer ISBN: 3030008177 Category : Medical Languages : en Pages : 505
Book Description
Over the last two decades, the recognition that astrocytes - the predominant type of cortical glial cells - could sense neighboring neuronal activity and release neuroactive agents, has been instrumental in the uncovering of many roles that these cells could play in brain processing and the storage of information. These findings initiated a conceptual revolution that leads to rethinking how brain communication works since they imply that information travels and is processed not just in the neuronal circuitry but in an expanded neuron-glial network. On the other hand the physiological need for astrocyte signaling in brain information processing and the modes of action of these cells in computational tasks remain largely undefined. This is due, to a large extent, both to the lack of conclusive experimental evidence, and to a substantial lack of a theoretical framework to address modeling and characterization of the many possible astrocyte functions. This book that we propose aims at filling this gap, providing the first systematic computational approach to the complex, wide subject of neuron-glia interactions. The organization of the book is unique insofar as it considers a selection of “hot topics” in glia research that ideally brings together both the novelty of the recent experimental findings in the field and the modelling challenge that they bear. A chapter written by experimentalists, possibly in collaboration with theoreticians, will introduce each topic. The aim of this chapter, that we foresee less technical in its style than in conventional reviews, will be to provide a review as clear as possible, of what is “established” and what remains speculative (i.e. the open questions). Each topic will then be presented in its possible different aspects, by 2-3 chapters by theoreticians. These chapters will be edited in order to provide a “priming” reference for modeling neuron-glia interactions, suitable both for the graduate student and the professional researcher.
Author: Michele Giugliano Publisher: Springer Nature ISBN: 3030894398 Category : Medical Languages : en Pages : 361
Book Description
This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author: Maria Kukley Publisher: Springer Nature ISBN: 1071637428 Category : Glutamic acid Languages : en Pages : 378
Book Description
Zusammenfassung: This volume explores the latest technologies used to study the co-existence of neuronal and neuron-glia synapses in the brain. The chapters in this volume are organized into three parts. Part One covers recent advancements in the technical approaches for studying glutamatergic signalling between neurons. Part Two highlights approaches to study the functional role of astrocytes at neuronal synapses. Part Three focuses on fast signalling at neuron-glia synapses, and highlights relevant methods for investigating these unusual synapses, including slice electrophysiology and in vivo gene delivery techniques. In the Neuromethods series style, all chapters contain key advices from experts in the field that are valuable for performing successful experiments on the topic in your laboratory. Cutting-edge and thorough, New Technologies for Glutamate Interactions: Neurons and Glia is a valuable resource for both neuronal and glial physiologists who are interested in learning about and developing new methods to further understand neuronal and neuron-glia synaptic transmission
Author: Boris Kryzhanovsky Publisher: Springer Nature ISBN: 3031448650 Category : Technology & Engineering Languages : en Pages : 505
Book Description
This book describes new theories and applications of artificial neural networks, with a special focus on answering questions in neuroscience, biology and biophysics and cognitive research. It covers a wide range of methods and technologies, including deep neural networks, large-scale neural models, brain–computer interface, signal processing methods, as well as models of perception, studies on emotion recognition, self-organization and many more. The book includes both selected and invited papers presented at the XXV International Conference on Neuroinformatics, held on October 23-27, 2023, in Moscow, Russia.
Author: De-Shuang Huang Publisher: Springer ISBN: 3319633120 Category : Computers Languages : en Pages : 822
Book Description
This three-volume set LNCS 10361, LNCS 10362, and LNAI 10363 constitutes the refereed proceedings of the 13th International Conference on Intelligent Computing, ICIC 2017, held in Liverpool, UK, in August 2017. The 221 full papers and 15 short papers of the three proceedings volumes were carefully reviewed and selected from 639 submissions. This second volume of the set comprises 74 papers. The papers are organized in topical sections such as Pattern Recognition; Image Processing; Virtual Reality and Human-Computer Interaction; Healthcare Informatics Theory and Methods; Genetic Algorithms; Blind Source Separation; Intelligent Fault Diagnosis; Machine Learning; Knowledge Discovery and Data Mining; Gene Expression Array Analysis; Systems Biology; Modeling, Simulation, and Optimization of Biological Systems; Intelligent Computing in Computational Biology; Computational Genomics; Computational Proteomics; Gene Regulation Modeling and Analysis; SNPs and Haplotype Analysis; Protein-Protein Interaction Prediction; Protein Structure and Function Prediction; Next-Gen Sequencing and Metagenomics; Structure Prediction and Folding; Biomarker Discovery; Applications of Machine Learning Techniques to Computational Proteomics, Genomics, and Biological Sequence Analysis; Biomedical Image Analysis; Human-Machine Interaction: Shaping Tools Which Will Shape Us; Protein and Gene Bioinformatics: Analysis, Algorithms and Applications; Special Session on Computer Vision based Navigation; Neural Networks: Theory and Application.
Author: Boris Kryzhanovsky Publisher: Springer Nature ISBN: 3031190327 Category : Technology & Engineering Languages : en Pages : 585
Book Description
This book describes new theories and applications of artificial neural networks, with a special focus on answering questions in neuroscience, biology and biophysics and cognitive research. It covers a wide range of methods and technologies, including deep neural networks, large-scale neural models, brain–computer interface, signal processing methods, as well as models of perception, studies on emotion recognition, self-organization and many more. The book includes both selected and invited papers presented at the XXIV International Conference on Neuroinformatics, held on October 17–21, 2022, in Moscow, Russia.
Author: Maurizio De Pittà
Author: Maurizio De Pittà
Author: Axel Sandvig
Author: Michele Giugliano
Author: Si Wu
Author: Maria Kukley
Author: Si Wu
Author: Boris Kryzhanovsky
Author: De-Shuang Huang
Author: Felix Schürmann
Author: Boris Kryzhanovsky