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Drug Discovery and Drug Development

Drug Discovery and Drug Development PDF Author: Madhu Dikshit
Publisher: Springer Nature
ISBN: 9811580022
Category : Medical
Languages : en
Pages : 376

Book Description
Over the years, India has attained a prominent global position in the manufacture of Generic Drugs. This success can be attributed to its synthetic organic chemistry and chemical engineering strengths, nurtured by the timely policies of the Government of India. However, breakthrough successes in New Drug Discovery have remained elusive, despite the brilliant and sustained efforts of many Indian researchers and Pharma establishments. The Indian National Science Academy thought it appropriate to document India’s New Drug Discovery Research (NDDR) journey to date. Gathering contributions from prominent researchers in the Indian Pharma Industry and Academia, this book highlights their efforts, achievements, and the status quo of Indian NDDR.

Drug Discovery and Drug Development

Drug Discovery and Drug Development PDF Author: Madhu Dikshit
Publisher: Springer Nature
ISBN: 9811580022
Category : Medical
Languages : en
Pages : 376

Book Description
Over the years, India has attained a prominent global position in the manufacture of Generic Drugs. This success can be attributed to its synthetic organic chemistry and chemical engineering strengths, nurtured by the timely policies of the Government of India. However, breakthrough successes in New Drug Discovery have remained elusive, despite the brilliant and sustained efforts of many Indian researchers and Pharma establishments. The Indian National Science Academy thought it appropriate to document India’s New Drug Discovery Research (NDDR) journey to date. Gathering contributions from prominent researchers in the Indian Pharma Industry and Academia, this book highlights their efforts, achievements, and the status quo of Indian NDDR.

Research and Development in the Pharmaceutical Industry (A CBO Study)

Research and Development in the Pharmaceutical Industry (A CBO Study) PDF Author: Congressional Budget Office
Publisher: Lulu.com
ISBN: 1304121445
Category : Science
Languages : en
Pages : 65

Book Description
Perceptions that the pace of new-drug development has slowed and that the pharmaceutical industry is highly profitable have sparked concerns that significant problems loom for future drug development. This Congressional Budget Office (CBO) study-prepared at the request of the Senate Majority Leader-reviews basic facts about the drug industry's recent spending on research and development (R&D) and its output of new drugs. The study also examines issues relating to the costs of R&D, the federal government's role in pharmaceutical research, the performance of the pharmaceutical industry in developing innovative drugs, and the role of expected profits in private firms' decisions about investing in drug R&D. In keeping with CBO's mandate to provide objective, impartial analysis, the study makes no recommendations. David H. Austin prepared this report under the supervision of Joseph Kile and David Moore. Colin Baker provided valuable consultation...

The Evolution of Drug Discovery

The Evolution of Drug Discovery PDF Author: Enrique Ravina
Publisher: John Wiley & Sons
ISBN: 3527326693
Category : Medical
Languages : en
Pages : 531

Book Description
Der Band zeichnet die oft spektakulären Erfolgs- oder Misserfolgsgeschichten neuartiger pharmazeutischer Wirkstoffe nach und nimmt den Leser dabei mit auf die Reise von den ersten Anfängen der Heilkunde bis zum Milliardengeschäft der modernen Pharmaindustrie. Sachkundig geschrieben, reich illustriert, anregend: Eine unterhaltsame Lektüre!

Drug Discovery and Development, Volume 1

Drug Discovery and Development, Volume 1 PDF Author: Mukund S. Chorghade
Publisher: Wiley-Interscience
ISBN: 9780471398486
Category : Science
Languages : en
Pages : 476

Book Description
From first principles to real-world applications -- here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines--from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development--from initial conceptualization to commercialization to clinicians and medical practitioners. Volume 1: Drug Discovery describes all the steps in the discovery process, including conceptualizing a drug, creating a library of candidates for testing, screening candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and modifying a drug as necessary. Volume 2: Drug Development delves into the nitty-gritty details of optimizing the synthetic route, drug manufacturing, outsourcing, and marketing--including drug coloring and delivery methods. Featuring contributions from a world-class team of experts, Drug Discovery and Development: * Features fascinating case studies, including the discovery and development of erythromycin analogs, Tagamet, and Ultiva (remifentanil) * Discusses the discovery of medications for bacterial infections, Parkinson's disease, psoriasis, peptic ulcers, atopic dermatitis, asthma, and cancer * Includes chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics Drug Discovery and Development is an indispensable working resource for industrialchemists, biologists, biochemists, and executives who work in the pharmaceutical industry.

Indian Patent Law and Practice

Indian Patent Law and Practice PDF Author: K.C. Kankanala
Publisher: OUP India
ISBN: 0198089600
Category : Law
Languages : en
Pages : 377

Book Description
This book is a practical and comprehensive reference work on Indian patent law covering various aspects of patent law and focusing on relevant cases and illustrations.

Drug Discovery and Drug Development

Drug Discovery and Drug Development PDF Author: Madhu Dikshit
Publisher:
ISBN: 9789811580031
Category :
Languages : en
Pages : 0

Book Description
Over the years, India has attained a prominent global position in the manufacture of Generic Drugs. This success can be attributed to its synthetic organic chemistry and chemical engineering strengths, nurtured by the timely policies of the Government of India. However, breakthrough successes in New Drug Discovery have remained elusive, despite the brilliant and sustained efforts of many Indian researchers and Pharma establishments. The Indian National Science Academy thought it appropriate to document India's New Drug Discovery Research (NDDR) journey to date. Gathering contributions from prominent researchers in the Indian Pharma Industry and Academia, this book highlights their efforts, achievements, and the status quo of Indian NDDR. .

Renewable Energy Finance: Powering The Future

Renewable Energy Finance: Powering The Future PDF Author: Charles W Donovan
Publisher: World Scientific
ISBN: 178326778X
Category : Business & Economics
Languages : en
Pages : 366

Book Description
The future of clean energy is no longer about science and technology; it's all about access to finance. The fossil fuel industry has been subsidized for decades with tax breaks and government backing, while renewables have struggled to compete. But now clean energy is the safe bet for investors, as is argued in Renewable Energy Finance: Powering the Future, edited by Dr Charles Donovan, Principal Teaching Fellow at Imperial College Business School.With a foreword by Lord Brown and contributions from some of the world's leading experts in energy finance, this timely book documents how investors are spending over US$250 billion each year on new renewable energy projects and positioning themselves in a global investment market that will continue to expand at double-digit growth rates until 2020. It documents first-hand experiences of the challenges of balancing risk and return amid volatile market conditions and rapid shifts in government policy.Renewable Energy Finance provides an insider's perspective on renewable energy transactions, and insight into how countries like the US, India and China are responding to the global energy challenge. Drawing together contributions from senior executives and leading academics, Renewable Energy Finance serves an audience of readers craving intelligent, practical perspectives on the future of clean energy investment.

Sphingolipids in Disease

Sphingolipids in Disease PDF Author: Erich Gulbins
Publisher: Springer
ISBN: 9783709117453
Category : Medical
Languages : en
Pages : 478

Book Description
Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease. ​

Fungi and their Role in Sustainable Development: Current Perspectives

Fungi and their Role in Sustainable Development: Current Perspectives PDF Author: Praveen Gehlot
Publisher: Springer
ISBN: 9789811344046
Category : Medical
Languages : en
Pages : 0

Book Description
This book illustrates the multiple roles of fungi in everyday life. Fungi are the large group of organisms with tremendous diversity and economic importance. Their ability to produce commercially efficient useful products makes them the vulnerable sustainable tool for the future generation. This book describes a systems approach and provides a means to share the latest developments and advances about the benefits of fungi including their wide application, traditional uses, modern practices, along with designing of strategies to harness their potential. The chapters are organized with data, providing information related to different sustainable aspects of fungi in agriculture, its cultivation and conservation strategies, industrial and environmental utilization, advanced bioconversion technologies and modern biotechnological interventions. Updated information and current opinion related to its application for sustainable agriculture, environment, and industries as futuristic tools have been presented and discussed in different chapters. The book also elucidates a comprehensive yet a representative description of the challenges associated with the sustained application of fungi to achieve the goals of sustainability.

Introduction To Radiobiology

Introduction To Radiobiology PDF Author: Maurice Tubiana
Publisher: CRC Press
ISBN: 0203983661
Category : Medical
Languages : en
Pages : 269

Book Description
This textbook covers many aspects of radiation, radiotherapy and their effects. It includes a discussion of recent advances, such as the molecular basis of cellular effects and cell radiosensitivity, radiocarcinogenesis and how radiotherapy can affect normal and neoplastic tissues.