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Clinical Pharmacokinetics

Clinical Pharmacokinetics PDF Author: John E. Murphy
Publisher:
ISBN: 9781585285365
Category : Pharmacokinetics
Languages : en
Pages : 0

Book Description
In the evolving practice of pharmacokinetics (PK), it is important to keep on top of the latest advances. John E. Murphy, a well-known leader in the field of clinical pharmacokinetics, has updated and expanded his widely-used textbook and reference. Clinical Pharmacokinetics, Sixth Edition includes the most current information, covering issues such as rational use of drug concentration measurements, changes in dosing obese patients, and considerations for a wider variety of drugs for special populations. There is also a new chapter focused on pharmacogenomics and its impact on pharmacokinetic parameters, as well as discussion of pharmacogenomics throughout the book. The new edition includes everything you need to know about pharmacokinetics today: Drugs, dosing, and therapeutic. Drug concentration measurements. New chapter on the impact of pharmacogenomics. Neonatal, pediatric, obese, and geriatric dosing. Dosing in renal disease and creatinine clearance estimation. Drugs sorted by family and as single drugs. Written in a straightforward style, with numerous charts and lists, the sixth edition makes complicated dosing and monitoring information easy to find and understand. Whether you are a student or practitioner, it is a resource you will turn to for reliable guidance throughout your pharmacy career.

Clinical Pharmacokinetics

Clinical Pharmacokinetics PDF Author: John E. Murphy
Publisher:
ISBN: 9781585285365
Category : Pharmacokinetics
Languages : en
Pages : 0

Book Description
In the evolving practice of pharmacokinetics (PK), it is important to keep on top of the latest advances. John E. Murphy, a well-known leader in the field of clinical pharmacokinetics, has updated and expanded his widely-used textbook and reference. Clinical Pharmacokinetics, Sixth Edition includes the most current information, covering issues such as rational use of drug concentration measurements, changes in dosing obese patients, and considerations for a wider variety of drugs for special populations. There is also a new chapter focused on pharmacogenomics and its impact on pharmacokinetic parameters, as well as discussion of pharmacogenomics throughout the book. The new edition includes everything you need to know about pharmacokinetics today: Drugs, dosing, and therapeutic. Drug concentration measurements. New chapter on the impact of pharmacogenomics. Neonatal, pediatric, obese, and geriatric dosing. Dosing in renal disease and creatinine clearance estimation. Drugs sorted by family and as single drugs. Written in a straightforward style, with numerous charts and lists, the sixth edition makes complicated dosing and monitoring information easy to find and understand. Whether you are a student or practitioner, it is a resource you will turn to for reliable guidance throughout your pharmacy career.

Casebook in Clinical Pharmacokinetics and Drug Dosing

Casebook in Clinical Pharmacokinetics and Drug Dosing PDF Author: Henry Cohen
Publisher: McGraw Hill Professional
ISBN: 0071832769
Category : Medical
Languages : en
Pages : 300

Book Description
A STEP-BY-STEP APPROACH TO DESIGNING ACCURATE DOSING REGIMENS Casebook in Pharmacokinetics and Drug Dosing uses real-life cases to teach pharmacy students, pharmacists, and clinical pharmacists how to apply pharmacokinetics to formulate proper dosing regimens. In order to be as clinically relevant as possible, the book not only discusses drugs with readily available therapeutic serum levels, but places equal emphasis on high-alert agents with narrow therapeutic indexes. Each drug chapter is written by clinical pharmacists who have hands-on experience in drug dosing and includes an overview of the drug’s pharmacology, including: Indications Mec hanisms of action Toxicities Pharmacokinetics There is comprehensive review and discussion of each drug's bioavailability, volume of distribution, clearance, half-life, therapeutic drug level monitoring, drug interactions, dosing, and availability. Each chapter is enhanced by numerous patient cases with clear step-by-step answers and explanations. Calculations, equations, and dosing recommendations are provided for each case.

Winter's Basic Clinical Pharmacokinetics

Winter's Basic Clinical Pharmacokinetics PDF Author: Paul Beringer
Publisher: LWW
ISBN: 9781496346421
Category : Clinical pharmacology
Languages : en
Pages : 0

Book Description
Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help pharmacy students in clinical settings and busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among students, clinical professors, and practitioners. Part I provides a basic review of pharmacokinetic principles, with extensive explanations, graphic illustrations, and detailed algorithms. Part II explains the clinical applications of these principles to problems commonly encountered in the practice setting with specific drugs. This edition includes the latest information on the clinical use of serum drug concentrations. New case studies and examples demonstrate the application of pharmacokinetics in today's clinical practice.

Clinical Pharmacokinetics

Clinical Pharmacokinetics PDF Author: John E. Murphy
Publisher:
ISBN: 9781585287000
Category : Medical
Languages : en
Pages : 0

Book Description
In the evolving practice of pharmacokinetics (PK), it is important to keep on top of the latest advances. John E. Murphy, Pharm.D., FASHP, FCCP, a well-known leader in the field of clinical pharmacokinetics, has updated and expanded his widely used textbook and reference. Clinical Pharmacokinetics, 7th Edition, includes the most current information, covering issues such as rational use of drug concentration measurements, changes in dosing obese patients, and considerations for a wider variety of drugs for special populations. Everything You Need to Know About PK Today Drugs, dosing, and therapeutic monitoring Drug concentration measurements New chapter on the impact of pharmacogenomics Neonatal, pediatric, obese, and geriatric dosing Dosing in renal disease and creatinine clearance estimation Drugs sorted by family and as single drugs The companion workbook Clinical Pharmacokinetics, 7th Edition: Workbook, designed to test skills for using equations and the application of pharmacokinetic parameters, contains questions and exercises with answers and detailed solutions to help gauge understanding. This title is sold as a compelte set containing the text and workbook. They are not available for sale separately.

Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications

Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications PDF Author: Hartmut Derendorf
Publisher: Lippincott Williams & Wilkins
ISBN: 1496385896
Category : Medical
Languages : en
Pages : 864

Book Description
Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.

Clinical Pharmacokinetics

Clinical Pharmacokinetics PDF Author: Soraya Dhillon
Publisher: Pharmaceutical Press
ISBN: 9780853695714
Category : Chemotherapy
Languages : en
Pages : 284

Book Description
Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles is to individualise the dose of drug, and optimise the outcome achieved in each patient. Its application reduces the chance of under-treatment, inadvertent poisoning, and dose related adverse effects. This new edition is specifically aimed at supporting undergraduate studies in pharmacokinetics, and has a strong emphasis on the application of pharmacokinetics in routine clinical practice. Clinical Pharmacokinetics also includes several case studies and 'questions and answers' to further aid understanding and revision.

Applied Clinical Pharmacokinetics

Applied Clinical Pharmacokinetics PDF Author: Larry A. Bauer
Publisher: McGraw Hill Professional
ISBN: 0071593721
Category : Medical
Languages : en
Pages : 842

Book Description
New sections on dosing strategies in all chapters. New chapter on sirolimus under the Immunosuppressants section. Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure. 30% of chapters extensively revised, others lightly updated

Concepts in Clinical Pharmacokinetics

Concepts in Clinical Pharmacokinetics PDF Author: Robin Southwood
Publisher:
ISBN: 9781585285914
Category : Medical
Languages : en
Pages : 0

Book Description
Understanding the science of pharmacokinetics is a challenge for many pharmacy students and practitioners. Concepts in Clinical Pharmacokinetics, now in its 7th edition, has helped thousands by simplifying this essential, but complex, subject to reflect current practice. The 7th edition has been revised by Robin Southwood, PharmD, BC-ADM, CDE; Virginia H. Fleming, PharmD, BCPS; and Gary Huckaby, PharmD; all experts in clinical pharmacy education. Together, they have updated and expanded the text to include the latest information and insights on concepts through extensive use of correlates, figures, and review questions. Inside you will find: 15 easy-to-follow lessons, perfect for a semester Practice quizzes to help chart progress Enhanced discussion of hemodialysis A phenytoin "cheat sheet" to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations Expanded information on modified diet in renal disease formula versus Cockcroft-Gault formula methods Factors to consider when choosing a dosing/body weight for various equations Updated clinical correlates, discussion points, references, and questions/answers Concepts in Clinical Pharmacokinetics is the fundamental reference for learning the basic, foundational pharmacokinetics concepts and how to apply them in clinical practice.

Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents

Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents PDF Author: Michael W. Jann
Publisher: Springer
ISBN: 3319278835
Category : Medical
Languages : en
Pages : 597

Book Description
This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs from the laboratory bench to use in patient care are discussed, including imaging techniques, genetics and physiological barriers, such as the blood-brain barrier. The second section describes the characteristics of specific agents,nominally arranged intodifferent therapeutic categories and with reference crossover use in different disease states. The pharmacologic characteristics of different drug formulations are explored in the context of their ability to improve patient adherence. The third section focuses on drug-drug interactions.Psychotropic medications from different categories are frequently prescribed together,or alongside medications used to treat comorbid conditions, and the information provided is directly relevant to the clinic, as a result. The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology.Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions,isfrequently updated. However, with information presented on a host of different platforms, and in different formats, obtaining the full picture can be difficult. This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.

Biopharmaceutics and Clinical Pharmacokinetics

Biopharmaceutics and Clinical Pharmacokinetics PDF Author: Notari
Publisher: Routledge
ISBN: 1351463845
Category : Science
Languages : en
Pages : 287

Book Description
For a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics. Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses. Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics. As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.