Chronic Obstructive Pulmonary Disease Exacerbations PDF Download

Author: Jadwiga A. Wedzicha
Publisher: CRC Press
ISBN: 1420070878
Category : Medical
Languages : en
Pages : 476

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Book Description
Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbat

Author: Nikos Siafakas
Publisher: CRC Press
ISBN: 0203913000
Category : Medical
Languages : en
Pages : 635

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Book Description
This text aids practitioners who seek to diagnose, treat and manage patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) more effectively. It discusses pulmonary gas exchange, muscle function and breathing, water/electrolyte imbalances and end-stage disease.

Author: Luigi Allegra
Publisher: Springer Science & Business Media
ISBN: 8847022010
Category : Medical
Languages : en
Pages : 136

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Book Description
A flood of data indicate the importance and the relevance in both respiratory and extrapulmonary disease of Chlamydia pneumoniae infection today. Antibody prevalence rates in Western countries reach 50% in the adult population and remain high in old age suggesting a high rate of reinfection. Chlamydia pneumoniae can cause upper respiratory tract infections, like pharyngitis and sinusitis as well as bronchitis and more than 10% of community-acquired pneumonia. Recent data suggest a possible association of Chlamydia pneumoniae infection with wheezing and adult-onset asthma. However, the most intriguing hypothesis pertains the possible association between Chlamydia pneumoniae infection and atherosclerosis.

Author: Graeme P. Currie
Publisher: John Wiley & Sons
ISBN: 1444329480
Category : Medical
Languages : en
Pages : 209

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Book Description
Chronic Obstructive Pulmonary Disease (COPD) is a progressive, largely irreversible lung condition characterised by airflow obstruction. Although cigarette smoking is the single most important risk factor in its development, other associations and risk factors are thought to have increasing relevance throughout the world. COPD is usually managed in primary care, although it is commonly under-diagnosed, and is one of the most common medical conditions necessitating admission to hospital. The second edition of the ABC of COPD provides the entire multidisciplinary team with a reliable, up-to-date and accessible account of COPD. Extensively updated by experienced clinicians - including new chapters on spirometry, inhalers, oxygen, death, dying and end of life issues - this ABC is an authoritative and practical guide for general practitioners, practice nurses, specialist nurses, medical students, paramedical staff, junior doctors, non-specialist doctors and all other health professionals working in both primary and secondary care.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309212197
Category : Medical
Languages : en
Pages : 200

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Book Description
Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data-including population surveys, cohort studies, disease registries, administrative health data, and vital statistics-contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

Author: Nicola A. Hanania
Publisher: Springer Science & Business Media
ISBN: 1597453579
Category : Medical
Languages : en
Pages : 324

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Book Description
Chronic obstructive pulmonary disease (COPD) affects millions of people across the world. COPD is not only a major burden to patients but is also costly and results in billions of dollars of direct and indirect costs annually. In recent years and with advancement of science, the understanding of COPD has improved significantly. Fortunately, current management guidelines consider COPD a preventable and treatable condition, and recent studies clearly indicate that available pharmacological and non-pharmacological interventions may improve various clinical outcomes. COPD: A Guide to Diagnosis and Clinical Management offers an exciting, evidence-based assessment of the field and will be of significant interest to clinicians who care for patients with COPD, including primary care providers and specialists. Comprehensive and state-of-the-art, this title is authored by experts who took the task of developing a resource that focuses on the essential issues in caring for patients with COPD. The first four chapters of the book cover major points about the systemic nature of COPD, the clinical and physiological assessments, and the outcome measures and prognostic markers. In the following section, various pharmacologic and non-pharmacological management strategies are reviewed based on the available evidence. The final sections outline the non-pulmonary effects of COPD and their management. COPD: A Guide to Diagnosis and Clinical Management is a vital, evidence-based text that will prove invaluable for all clinicians who care for patients with this debilitating disorder.

Author: Antonio Anzueto
Publisher: European Respiratory Society
ISBN: 1849840644
Category : Medical
Languages : en
Pages : 341

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Book Description
COPD is one of the most common diseases worldwide and is projected to be the third leading cause of death by 2020. But that does not mean it is easy to understand or manage. In everyday practice, pulmonologists face areas of controversy in COPD, for which evidence-based medicine is often unavailable. This ERS Monograph considers where the current controversies in COPD lie, discussing areas such as screening, premature birth, asthma–COPD overlap syndrome, treatment, rehabilitation and palliative care. This book will be of great interest to both clinicians and scientists, and aims to stimulate further discussion about this diverse and fascinating disease. "...contains a vast amount of information on the disease, its prevalence, signs and symptoms, diagnositc tests and treatment options. The book's format makes it quick and simple to find out what you need to know, and its size would make it easy to take to work for use in practice [...] invaluable for anyone working with patients with the disease." Emma Vincent, Nursing Standard

Author: Stephan A. Mayer
Publisher: John Wiley & Sons
ISBN: 1119293308
Category : Medical
Languages : en
Pages : 658

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Book Description
Part of the Mount Sinai Expert Guide series, this outstanding book provides rapid-access, clinical information on all aspects of Critical Care with a focus on clinical diagnosis and effective patient management. With strong focus on the very best in multidisciplinary patient care, it is the ideal point of care consultation tool for the busy physician.

Author: Laura Labonté
Publisher:
ISBN:
Category :
Languages : en
Pages :

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"Chronic obstructive pulmonary disease (COPD) is one of the most under-diagnosed chronic diseases. Its burden is mostly attributable to exacerbations, acute events of worsened symptoms that lead to disease progression as well as significant morbidity and mortality. As many individuals remain undiagnosed, exacerbations are simply treated as acute events by healthcare providers. Through lack of proper disease management, these individuals will continue to experience exacerbations, and as disease progresses, will become susceptible to many comorbid conditions. Cardiovascular (CV) comorbidity is the second cause of death among COPD patients. However, some determinants of increased CV risk could be mediated using specific interventions. An important common link between CV disease and COPD is enhanced inflammation. As such, inflammatory mediators are attractive targets for modulating CV risk in COPD. The purpose of this thesis was to evaluate the wide range of impacts of COPD exacerbations, from population burdens, to CV risk, to inflammation in subjects representing different stages of disease using a translational research approach. Two research projects were carried out to address this objective. The first consisted of an analysis of exacerbation-like respiratory events among subjects with undiagnosed and previously diagnosed COPD, embedded within an existing population based cohort study called Canadian Cohort Obstructive Lung Disease (CanCOLD). Exacerbation-like respiratory events were measured in these subjects using a questionnaire administered every three months. Differences in the characteristics of subjects with undiagnosed and diagnosed COPD were assessed, as well as those associated with reporting exacerbation-like respiratory events. The proportion of subjects reporting events and odds of using health services were also compared. The second was a local study of diagnosed COPD patients hospitalized for exacerbations, who have advanced disease and elevated CV risk. A measure of arterial stiffness, carotid-femoral pulse wave velocity (cf-PWV), and powerful predictor of CV events, was measured sequentially in these patients, as well as several inflammatory mediators and other clinical variables. The associations between these were determined over time. In the CanCOLD cohort, subjects with undiagnosed COPD had milder symptoms, better lung function and less functional impairment compared to diagnosed subjects. However, lower health-related quality of life was associated with reporting exacerbation-like respiratory events in both groups of subjects. Although the proportion of subjects reporting these events was lower among undiagnosed subjects, health service utilization was similar to that of diagnosed subjects. Within the local study, several important predictors of increased cf-PWV over time were identified, including decline in lung function and subsequent exacerbations. Additionally, club cell (CC)-16, a lung-specific inflammatory mediator was identified as a determinant of changes in cf-PWV and exacerbation frequency over time. Moreover, RelB, a nuclear factor (NF)-[kappa]B family member and mediator of pulmonary inflammation, was identified as a potential novel mediator of CV function in COPD patients.This thesis demonstrates that, at the populational level, many subjects are not diagnosed for their COPD, but experience exacerbation-like respiratory events that result in a much greater utilization of health services than previously thought. With regards to CV morbidity, several novel predictors of arterial stiffening were identified; some of these representing potentially modifiable targets. CC-16 was identified as an important novel inflammatory link between pulmonary function and CV function in COPD patients. Consequently, the results of this thesis describe the wide range of impacts of exacerbations from populational burdens to inflammation." --

Author: William MacNee
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 310

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