Chiral Auxiliaries and Substrate Directable Reactions to Access Highly Functionalised Chiral Lactones PDF Download

Author: Iwan Rhydian Davies
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

View

Book Description

Author: D. Gangani Niyadurupola
Publisher:
ISBN:
Category :
Languages : en
Pages :

View

Book Description

Author: David John Ager
Publisher: CRC Press
ISBN: 0824746295
Category : Science
Languages : en
Pages : 395

View

Book Description
Describes the problems associated with large, commercial-scale syntheses of chiral molecules and the relatively small number of reactions that can be used to achieve these syntheses. The book discusses commercially viable and still-developing methods of compound manufacture, and reviews the best-selling chiral compounds as of 1996.

Author: Gregory Roos
Publisher: Academic Press
ISBN: 012417115X
Category : Science
Languages : en
Pages : 1271

View

Book Description
Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data. Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation. Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compounds Contains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource

Author: Jessica Marie Sligar
Publisher:
ISBN:
Category :
Languages : en
Pages : 120

View

Book Description
A variety of chiral auxiliaries have been synthesized from derivatives of natural products (I R, 2S)-ephedrine, (L)-valine and S-methyl-(L)-cysteine. These ligands were designed for use as chiral non-transferable ligands in organocuprate reactions. Different parameters such as solvent, the use of chiral additives and copper(l) salt have been studied and compared. Enantiomeric excesses as high as 64% have been obtained.

Author: Gregory Roos
Publisher: Academic Press
ISBN: 9780125953498
Category : Science
Languages : en
Pages : 1423

View

Book Description
The Compendium is a detailed compilation of chiral auxiliaries which are used in the field of organic chemistry to direct "asymmetric synthesis". A molecule is called chiral because it can have two "enantiomers" -- like left and right-handed molecules. An enantiomer is either of two molecules of the same chemical composition that are mirror images of each other but not identical. A "chiral auxiliary" is an aid / auxiliary used to specifically produce either the left or right enantiomer of the chosen molecule, as desired. In this comprehesive reference source, industrial chemists can make informed selections of an auxiliary for a specific application. It is fully cross-referenced to enable the comparative selection of auxiliaries. The work includes over 13,000 auxiliary reaction applications with complete reaction details of the synthetic routes, reagents, and primary literature references. Key Features * This remarkable major reference work is the first such compilation and represents the only total source for the diverse applications of auxiliaries * Thoroughly cross-referenced to enable comparative

Author: Jeffrey William Holman
Publisher:
ISBN:
Category :
Languages : en
Pages : 436

View

Book Description

Author: Mark E. McDonnell
Publisher:
ISBN:
Category : Macrolide antibiotics
Languages : en
Pages : 306

View

Book Description

Author: Chiara Ghiron
Publisher: OUP Oxford
ISBN: 0191546321
Category : Science
Languages : en
Pages : 140

View

Book Description
The book is comprised of a series of exercises in synthetic organic chemistry based around recent published syntheses. The exercises are designed to provide challenges for people with varying levels of experience from final year students to academic staff and industrial group leaders, allowing them to increase their `vocabulary' of synthetic transformations. This novel approach, which actively involves the reader, would be an ideal source of topics for group discussions.

Author: Tamejiro Hiyama
Publisher: John Wiley & Sons
ISBN: 3527344535
Category : Science
Languages : en
Pages : 566

View

Book Description
Provides a unique summary of important catalytic reactions in the presence of silicon A must-have for all synthetic chemists, this book summarizes all of the important developments in the application of organosilicon compounds in organic synthesis and catalysis. Edited by two world leaders in the field, it describes different approaches and covers a broad range of reactions, e.g. catalytic generation of silicon nucleophiles, Si-H Bond activation, C-H bond silylation, silicon-based cross-coupling reactions, and hydrosilylation in the presence of earth-abundant metals. In addition to the topics covered above, Organosilicon Chemistry: Novel Approaches and Reactions features chapters that look at Lewis base activation of silicon Lewis acids, silylenes as ligands in catalysis, and chiral silicon molecules. -The first book about this topic in decades, covering a broad range of reactions -Covers new approaches and novel catalyst systems that have been developed in recent years -Written by well-known, international experts in the areas of organometallic silicon chemistry and organosilicon cross-coupling reactions Organosilicon Chemistry: Novel Approaches and Reactions is an indispensable source of information for synthetic chemists in academia and industry, working in the field of organic synthesis, catalysis, and main-group chemistry.