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Author: Thomas O. Baldwin Publisher: Springer Science & Business Media ISBN: 1475796374 Category : Science Languages : en Pages : 358
Book Description
The Industry-University Cooperative Chemistry Program has sponsored seven previous international symposia covering a wide variety of topics of interest to industrial and academic chemists. The eighth IUCCP symposium, held March 19-22, 1990, at Texas A&M University, represents a deviation from the former symposia, in that it is the first of a two-symposium series dedicated to the rapidly moving new field of industrial biochemistry that has beco~e known as biotechnology. Biotechnology is really not a new discipline, but rather is a term coined to describe the new and exciting commercial applications of biochemistry. The development of the field of biotechnology is a direct result of recombinant DNA technology, which began in earnest about 15 years ago. Today, we can routinely do experiments that were inconceivable in the early 1970's. Only comparatively simple technology available even in small laboratories is required to synthesize a gene and from it, to produce vast amounts of biological materials of enormous commercial value. These technical developments and others have stimulated increased activities in the field of enzyme biotechnology, using enzymes to catalyze "unnatural" reactions to produce complex molecules with stereochemical precision. It is true today, we can readily produce DNA fragments that will encode any amino acid sequence that we might desire, but at this point, our foundation of basic knowledge falls short. The dream of "designer enzymes" is still a fantasy, but the current wave of research activity and exciting new developments suggest that in the future the dream may become a reality.
Author: Thomas O. Baldwin Publisher: Springer Science & Business Media ISBN: 1475796374 Category : Science Languages : en Pages : 358
Book Description
The Industry-University Cooperative Chemistry Program has sponsored seven previous international symposia covering a wide variety of topics of interest to industrial and academic chemists. The eighth IUCCP symposium, held March 19-22, 1990, at Texas A&M University, represents a deviation from the former symposia, in that it is the first of a two-symposium series dedicated to the rapidly moving new field of industrial biochemistry that has beco~e known as biotechnology. Biotechnology is really not a new discipline, but rather is a term coined to describe the new and exciting commercial applications of biochemistry. The development of the field of biotechnology is a direct result of recombinant DNA technology, which began in earnest about 15 years ago. Today, we can routinely do experiments that were inconceivable in the early 1970's. Only comparatively simple technology available even in small laboratories is required to synthesize a gene and from it, to produce vast amounts of biological materials of enormous commercial value. These technical developments and others have stimulated increased activities in the field of enzyme biotechnology, using enzymes to catalyze "unnatural" reactions to produce complex molecules with stereochemical precision. It is true today, we can readily produce DNA fragments that will encode any amino acid sequence that we might desire, but at this point, our foundation of basic knowledge falls short. The dream of "designer enzymes" is still a fantasy, but the current wave of research activity and exciting new developments suggest that in the future the dream may become a reality.
Author: Mohammed Kuddus Publisher: Academic Press ISBN: 0128132817 Category : Technology & Engineering Languages : en Pages : 912
Book Description
Enzymes in Food Biotechnology: Production, Applications, and Future Prospects presents a comprehensive review of enzyme research and the potential impact of enzymes on the food sector. This valuable reference brings together novel sources and technologies regarding enzymes in food production, food processing, food preservation, food engineering and food biotechnology that are useful for researchers, professionals and students. Discussions include the process of immobilization, thermal and operational stability, increased product specificity and specific activity, enzyme engineering, implementation of high-throughput techniques, screening to relatively unexplored environments, and the development of more efficient enzymes. - Explores recent scientific research to innovate novel, global ideas for new foods and enzyme engineering - Provides fundamental and advanced information on enzyme research for use in food biotechnology, including microbial, plant and animal enzymes - Includes recent cutting-edge research on the pharmaceutical uses of enzymes in the food industry
Author: T Palmer Publisher: Elsevier ISBN: 0857099922 Category : Technology & Engineering Languages : en Pages : 434
Book Description
In recent years, there have been considerable developments in techniques for the investigation and utilisation of enzymes. With the assistance of a co-author, this popular student textbook has been updated to include techniques such as membrane chromatography, aqueous phase partitioning, engineering recombinant proteins for purification and due to the rapid advances in bioinformatics/proteomics, a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy. Written with the student firmly in mind, no previous knowledge of biochemistry, and little of chemistry, is assumed. It is intended to provide an introduction to enzymology, and a balanced account of all the various theoretical and applied aspects of the subject which are likely to be included in a course. - Provides an introduction to enzymology and a balanced account of the theoretical and applied aspects of the subject - Discusses techniques such as membrane chromatography, aqueous phase partitioning and engineering recombinant proteins for purification - Includes a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy
Author: T. D. H. Bugg Publisher: John Wiley & Sons ISBN: 1118348990 Category : Science Languages : en Pages : 310
Book Description
Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach “catalytic perfection”. Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry. The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.
Author: National Research Council Publisher: National Academies Press ISBN: 0309316553 Category : Science Languages : en Pages : 158
Book Description
The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
Author: N.S. Punekar Publisher: Springer ISBN: 9811307857 Category : Science Languages : en Pages : 560
Book Description
This enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed for self-study, it explains how to plan enzyme experiments and subsequently analyze the data collected. The book is divided into five major sections: 1] Introduction to enzymes, 2] Practical aspects, 3] Kinetic Mechanisms, 4] Chemical Mechanisms, and 5] Enzymology Frontiers. Individual concepts are treated as stand-alone chapters; readers can explore any single concept with minimal cross-referencing to the rest of the book. Further, complex approaches requiring specialized techniques and involved experimentation (beyond the reach of an average laboratory) are covered in theory with suitable references to guide readers. The book provides students, researchers and academics in the broad area of biology with a sound theoretical and practical knowledge of enzymes. It also caters to those who do not have a practicing enzymologist to teach them the subject.
Author: Gregory A. Tucker Publisher: Springer Science & Business Media ISBN: 1461521475 Category : Technology & Engineering Languages : en Pages : 329
Book Description
Recent years have seen a rapid increase in the use of enzymes as food processing tools, as an understanding of their means of control has improved. Since publication of the first edition of this book many new products have been commercially produced and the corresponding number of published papers has swollen. This second edition has been fully revised and updated to cover changes in the last five years. It continues to provide food technologists, chemists, biochemists and microbiologists with an authoritative, practical and detailed review of the subject.
Author: Xiaoyu Wang Publisher: Springer ISBN: 3662530686 Category : Technology & Engineering Languages : en Pages : 134
Book Description
This book describes the fundamental concepts, the latest developments and the outlook of the field of nanozymes (i.e., the catalytic nanomaterials with enzymatic characteristics). As one of today’s most exciting fields, nanozyme research lies at the interface of chemistry, biology, materials science and nanotechnology. Each of the book’s six chapters explores advances in nanozymes. Following an introduction to the rise of nanozymes research in the course of research on natural enzymes and artificial enzymes in Chapter 1, Chapters 2 through 5 discuss different nanomaterials used to mimic various natural enzymes, from carbon-based and metal-based nanomaterials to metal oxide-based nanomaterials and other nanomaterials. In each of these chapters, the nanomaterials’ enzyme mimetic activities, catalytic mechanisms and key applications are covered. In closing, Chapter 6 addresses the current challenges and outlines further directions for nanozymes. Presenting extensive information on nanozymes and supplemented with a wealth of color illustrations and tables, the book offers an ideal guide for readers from disparate areas, including analytical chemistry, materials science, nanoscience and nanotechnology, biomedical and clinical engineering, environmental science and engineering, green chemistry, and novel catalysis.
Author: Athel Cornish-Bowden Publisher: Elsevier ISBN: 1483164675 Category : Science Languages : en Pages : 221
Book Description
Principles of Enzyme Kinetics discusses the principles of enzyme kinetics at an intermediate level. It is primarily written for first-year research students in enzyme kinetics. The book is composed of 10 chapters. Chapter 1 provides the basic principles of enzyme kinetics with a brief discussion of dimensional analysis. Subsequent chapters cover topics on the essential characteristics of steady-state kinetics, temperature dependence, methods for deriving steady-state rate equations, and control of enzyme activity. Integrated rate equations, and introductions to the study of fast reactions and the statistical aspects of enzyme kinetics are provided as well. Chemists and biochemists will find the book invaluable.
Author: Thomas O. Baldwin
Author: Thomas O. Baldwin
Author: Mohammed Kuddus
Author: T Palmer
Author: T. D. H. Bugg
Author: National Research Council
Author: N.S. Punekar
Author: 
Author: Gregory A. Tucker
Author: Xiaoyu Wang
Author: Athel Cornish-Bowden