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Author: David Albahari Publisher: Restless Books ISBN: 1632061937 Category : Fiction Languages : en Pages : 208
Book Description
From the award-winning Serbian author David Albahari comes a devastating and Kafkaesque war fable about an army unit sent to guard a military checkpoint with no idea where they are or who the enemy might be. Atop a hill, deep in the forest, an army unit is dropped off to guard a checkpoint. The commander doesn’t know where they are, what border they’re protecting, or why. Their map is useless. The radio crackles with a language no one can recognize. A soldier is found dead in a latrine and the unit vows vengeance—but the killer, like the enemy, is unknown. Amid orgies and massacres, the commander struggles to maintain order and keep his soldiers alive, but he can’t be sure whether they’re fighting a war or caught in some bizarre military experiment. Equal parts Waiting for Godot and Catch-22, David Albahari’s Checkpoint is a haunting and hysterical confrontation with the absurdity of war. Praise for Checkpoint: "A satirical take on war in the vein of Catch-22 and Slaughterhouse Five, Serbian author David Albahari’s Checkpointis shocking and comic in equal turns, skillfully pulled together by the force of Albahari’s wit.... Visceral, wild, and often hilarious, Checkpoint is a dark delight." —Ho Lin, Foreword Reviews, Starred Review “A worthy descendant of The Good Soldier Svejk and Catch-22.” —Kirkus Reviews “Checkpoint is a tornado of a book. David Albahari, a noted Serbian author who lives in Canada, muscles this Kafkaesque short novel into the war-is-absurd literary tradition in one tremendous 183-page paragraph…. Stylistically, JP Donleavy and Gary Shteyngart come to mind at times, while imagistically one might think of Goya, Picasso, or the Surrealists. But Albahari has a distinctive voice, and it comes through vividly in Ellen Elias-Bursać’s able translation from the Serbian.” —Jon Sobel, Blogcritics “Between adventure and apocalypse... Kafka and Kubrick...combining in grotesque-comical manner all the ridiculousness, beauty, horror, subtlety and extravagance that literature can hold.“ —Neue Zürcher Zeitung
Author: David Albahari Publisher: Restless Books ISBN: 1632061937 Category : Fiction Languages : en Pages : 208
Book Description
From the award-winning Serbian author David Albahari comes a devastating and Kafkaesque war fable about an army unit sent to guard a military checkpoint with no idea where they are or who the enemy might be. Atop a hill, deep in the forest, an army unit is dropped off to guard a checkpoint. The commander doesn’t know where they are, what border they’re protecting, or why. Their map is useless. The radio crackles with a language no one can recognize. A soldier is found dead in a latrine and the unit vows vengeance—but the killer, like the enemy, is unknown. Amid orgies and massacres, the commander struggles to maintain order and keep his soldiers alive, but he can’t be sure whether they’re fighting a war or caught in some bizarre military experiment. Equal parts Waiting for Godot and Catch-22, David Albahari’s Checkpoint is a haunting and hysterical confrontation with the absurdity of war. Praise for Checkpoint: "A satirical take on war in the vein of Catch-22 and Slaughterhouse Five, Serbian author David Albahari’s Checkpointis shocking and comic in equal turns, skillfully pulled together by the force of Albahari’s wit.... Visceral, wild, and often hilarious, Checkpoint is a dark delight." —Ho Lin, Foreword Reviews, Starred Review “A worthy descendant of The Good Soldier Svejk and Catch-22.” —Kirkus Reviews “Checkpoint is a tornado of a book. David Albahari, a noted Serbian author who lives in Canada, muscles this Kafkaesque short novel into the war-is-absurd literary tradition in one tremendous 183-page paragraph…. Stylistically, JP Donleavy and Gary Shteyngart come to mind at times, while imagistically one might think of Goya, Picasso, or the Surrealists. But Albahari has a distinctive voice, and it comes through vividly in Ellen Elias-Bursać’s able translation from the Serbian.” —Jon Sobel, Blogcritics “Between adventure and apocalypse... Kafka and Kubrick...combining in grotesque-comical manner all the ridiculousness, beauty, horror, subtlety and extravagance that literature can hold.“ —Neue Zürcher Zeitung
Author: Syngress Publisher: Elsevier ISBN: 0080476457 Category : Computers Languages : en Pages : 657
Book Description
Unparalleled security management that IT professionals have been waiting for. Check Point Software Technologies is the worldwide leader in securing the Internet. The company's Secure Virtual Network (SVN) architecture provides the infrastructure that enables secure and reliable Internet communications. CheckPoint recently announced a ground-breaking user interface that meets the computer industry's Internet security requirements. The Next Generation User Interface is easy to use and offers unparalleled security management capabilities by creating a visual picture of security operations. CheckPoint Next Generation Security Administration will be a comprehensive reference to CheckPoint's newest suite of products and will contain coverage of: Next Generation User Interface, Next Generation Management, Next Generation Performance, Next Generation VPN Clients, and Next Generation Systems. CheckPoint are a company to watch, they have captured over 50% of the VPN market and over 40% of the firewall market according to IDC Research Over 29,000 IT professionals are CheckPont Certified This is the first book to covers all components of CheckPoint's new suite of market-leading security products - it will be in demand!
Author: Yehudit Kirstein Keshet Publisher: Zed Books ISBN: 9781842777190 Category : History Languages : en Pages : 212
Book Description
This book is a critical exploration of Israel's curfew-closure policy in the Occupied Palestinian Territories through the eyes of CheckpointWatch, an organization of Israeli women monitoring human rights abuses. The book combines observers' daily reports from the checkpoints and along the Separation Wall, with analysis of the bureaucracy that supports the ongoing occupation. Keshet demonstrates the link between Israeli bureaucracy and the closure system as integral to a wider project of ethnic cleansing. As co-founder of the group, Keshet critically reviews the organisation's transformation from a feminist, radical protest movement to one both reclaimed by, and reclaiming, the consensus. Illustrating the nature of Israeli mainstream discourse as both anodyne and cruel, the book also analyses Israeli media representation of Checkpoint Watch and human rights activism in general. Keshet contends that the dilemmas of these Israeli women, torn between opposition to the Occupation and their loyalty to the state, reflects political divisions within Israel society as a whole.
Author: Marian Cox Publisher: Cambridge University Press ISBN: 1107690994 Category : Juvenile Nonfiction Languages : en Pages : 191
Book Description
The Cambridge Checkpoint English suite provides a comprehensive, structured resource which covers the Secondary 1 framework for English and seamlessly progresses into the next key stage (covered by our Cambridge IGCSE® First Language English series). This lively stage 8 Coursebook contains 12 themed units providing comprehensive coverage of the revised Cambridge Secondary 1 syllabus. As the core component in this suite, this title includes coverage of the five content areas (Phonics, Spelling and Vocabulary, Grammar and Punctuation, Reading, Writing, and Speaking and Listening). Additional features include rigorous language practice and teaching of key concepts, engaging activities to develop reading and writing skills, integrated speaking and listening tasks and a wide range of fiction and non-fiction texts from around the world. A skill-building, write-in workbook and a Teacher's Resource CD-ROM are available separately.
Author: György Ferenc Tóth Publisher: SUNY Press ISBN: 1438461216 Category : Social Science Languages : en Pages : 334
Book Description
A historical analysis of the transatlantic relations of the American Indian radical sovereignty movement of the late Cold War. From Wounded Knee to Checkpoint Charlie examines the history of the transatlantic alliance between American Indian sovereignty activists and Central European solidarity groups, and their entry into the United Nations in the 1970s and 1980s. In the late Cold War, Native American activists engaged in transnational diplomacy for nation building by putting outside pressure on the US government for a more progressive Indian policy that reached for the full decolonization of Native American communities into independence. By using extensive multinational archival research complemented by interviews, György Ferenc Tóth investigates how older transatlantic images of American Indians influenced the alliance between Native activists and Central European groups, how this coalition developed and functioned, and how the US government and the regimes of the Eastern Bloc responded to this transatlantic alliance. This book not only places the American Indian radical sovereignty movement in an international context, but also recasts it as a transnational struggle, thus connecting domestic US social and political history to the history of Cold War transatlantic relations and global movements.
Author: Axel H. Schönthal Publisher: Springer Science & Business Media ISBN: 1592597882 Category : Medical Languages : en Pages : 328
Book Description
Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the damage cannot be repaired. Moreover, internal errors can occur during the highly orchestrated replication of the cellular genome and its distribution into daughter cells. Here, the temporal order of these cell cycle events must be strictly enforced—for example, to ensure that DNA replication is c- plete and occurs only once before cell division, or to monitor mitotic spindle assembly, and to prevent exit from mitosis until chromosome segregation has been completed. Thus, well functioning checkpoint mechanisms are central to the maintenance of genomic integrity and the basic viability of cells and, the- fore, are essential for proper development and survival. The importance of proper functioning of checkpoints becomes plainly obvious under conditions in which this control network malfunctions and fails. Depending on the severity and timing, failure of this machinery can lead to embryonic lethality, genetic diseases, and cancer.
Author: Zahid H. Siddik Publisher: Springer Science & Business Media ISBN: 1607611783 Category : Medical Languages : en Pages : 276
Book Description
Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular proliferation, is an inherent characteristic of cancer. This loss may occur through aberration in any single component involved in signal transduction pathways that orchestrate checkpoint regulation, which may manifest through either a failure to activate the checkpoint or a failure to respond to the activated checkpoint. In normal cells, checkpoint pathways are activated when genetic or cellular homeostasis is compromised, and signals are then transduced to re-stabilize homeostasis, and, failing this, to activate the apoptotic machinery to induce a cellular suicidal response. This implies that both survival and cell death pathways are induced following checkpoint activation, and that the final decision is dependant on the net result of integrating the two sets of signals. It is intriguing that checkpoint pathways are also critical in cancer therapy to provide an apoptotic stimulus when cellular damage induced by the therapeutic agent is detected by the sensor system. Therefore, it is not surprising that failure in pro-survival checkpoint response will render tumor cells hypersensitive to cytotoxics and, conversely, failure in pro-apoptotic checkpoint response will induce genetic instability and/or therapeutic resistance. Understanding the intricacies of checkpoint response is, therefore, central to the design of therapeutic regimen that will enhance antitumor effects. Although early versions of this design entail combination of cytotoxic agents with cell cycle or checkpoint inhibitors, a greater understanding of the concepts could make such combinations clinically more effective. The contributions in this book will consolidate the current state of knowledge on checkpoint responses that may lay the foundation for hypothesis-driven rational approaches in advancing the management of cancer. The immediate attraction of the book to the scientific community is that it represents a timely opportunity to build upon existing concepts of checkpoints to expand our understanding of the inner workings of the critical checkpoint machinery. The present understanding has provided ample appreciation that response to checkpoint activation is manifested through coordinated inhibition of cyclin-dependent kinase (CDK) complexes in G1, S and/or the G2 phase in order to arrest the cell cycle. Kinase inhibition can occur through several mechanisms, including inhibitory phosphorylation of CDK, destruction of the cognate cyclins, and recruitment of CDK inhibitors from the INK and WAF1/CIP1 families. However, the wealth of information from recent discoveries needs to be examined critically to consolidate our conceptual knowledge of checkpoints. At the same time, there is acute awareness in the diversity of checkpoint response between cytotoxic agents, and this serves as a reminder of the magnitude of complexity that is inherent in checkpoint regulation. This volume is intended to bring the cancer research community closer toward an improved understanding of this regulation, how checkpoint abnormalities can impact negatively on cancer therapy, and emerging strategies to target checkpoint response as a therapeutic end-point.
Author: Brian Mills Publisher: Tyndale House ISBN: 1612913768 Category : Young Adult Nonfiction Languages : en Pages : 167
Book Description
Society today rejects the idea of absolute truth and is openly hostile toward God. For boys who want to be more like Christ, going through adolescence in this culture is like crossing a minefield without a map. They need parents and youth workers to engage with them early and equip them with the skills needed to thrive. Checkpoints plots a course through this enemy territory that not only steers young men toward godliness but also explains how to avoid potential pitfalls. Checkpoints honestly talks about the core issues boys face, opening a vital dialogue between fathers and sons, pastors and students. Key takeaways: Created by student pastors with 20+ years in ministry 8 lessons Written in a devotional style Guys spend just 15 minutes each day to prepare them for their small group time.
Author: Howard B. Lieberman Publisher: Springer Science & Business Media ISBN: 1592596460 Category : Science Languages : en Pages : 366
Book Description
The field of cell cycle regulation is based on the observation that the life cycle of a cell progresses through several distinct phases, G1, M, S, and G2, occurring in a well-defined temporal order. Details of the mechanisms involved are rapidly emerging and appear extraordinarily complex. Furthermore, not only is the order of the phases important, but in normal eukaryotic cells one phase will not begin unless the prior phase is completed successfully. Che- point control mechanisms are essentially surveillance systems that monitor the events in each phase, and assure that the cell does not progress prematurely to the next phase. If conditions are such that the cell is not ready to progress—for example, because of incomplete DNA replication in S or DNA damage that may interfere with chromosome segregation in M—a transient delay in cell cycle progression will occur. Once the inducing event is properly handled— for example, DNA replication is no longer blocked or damaged DNA is repaired—cell cycle progression continues. Checkpoint controls have recently been the focus of intense study by investigators interested in mechanisms that regulate the cell cycle. Furthermore, the relationship between checkpoint c- trol and carcinogenesis has additionally enhanced interest in these cell cycle regulatory pathways. It is clear that cancer cells often lack these checkpoints and exhibit genomic instability as a result. Moreover, several tumor suppressor genes participate in checkpoint control, and alterations in these genes are as- ciated with genomic instability as well as the development of cancer.