Cerebrospinal Fluid in Neurologic Disorders PDF Download

Author:
Publisher: Elsevier
ISBN: 9780128042793
Category : Medical
Languages : en
Pages : 320

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Book Description
Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker Addresses relevant research in context with the most important diagnostic entities in neurology Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available

Author: Florian Deisenhammer
Publisher: Springer
ISBN: 3319012258
Category : Medical
Languages : en
Pages : 442

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Book Description
The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.

Author: Joseph R. Bianchine
Publisher: Springer
ISBN: 1489933727
Category : Medical
Languages : en
Pages : 330

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Book Description
Scientists have speculated as to the nature of cerebrospinal fluid (CSF) - "the third circulation" or "vital spirit" for centuries. Just what is this mysterious bathing solution of the central nervous system? Is it a vehicle of transport for an "animal spirit" directing all our activities, as thought by Galen (Singer, 1956) or but a "modified tap water" (Halliburton, 1917)? With the advent of lumbar puncture, cerebrospinal fluid has become a readily available and important means of studying disease affecting the nervous system. In recent years, many sophisticated tools including com puter guided gas chromatography/mass spectrometry and high performance liquid chromatography have made it possible to identify and quantify many constituents of this fluid. The CSF has an enormous, though largely "untapped", potential in aiding diagnosis and evaluating treatment of many neurological, psychiatric and systemic disorders. As the ependyma is only a diffusional barrier between the CSF and extracellular fluid of the brain for many compounds, changes in the concentration of these compounds in the CSF may reflect disease processes in the brain.

Author: Robert A. Fishman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 456

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Book Description
This comprehensive and authoritative text covers the anatomical and physiological aspects of cerebrospinal fluid. Also includes material on differential diagnosis, AIDS, neuro-oncology, psychiatric disorders, and the composition and clinical examination of cerebrospinal fluid, including a detailed discussion on the treatment of complications of the lumbar puncture.

Author: John Brust
Publisher: McGraw Hill Professional
ISBN: 0071701184
Category : Medical
Languages : en
Pages : 593

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Book Description
A handy, practical, and management-oriented neurology sourcebook – delivering everything you need in one easy-to-carry volume CURRENT Diagnosis & Treatment Neurology, 2e provides busy clinicians with practical, up-to-date strategies for assessing and managing the most frequently seen neurologic conditions in adults and children. Features Consistent presentation includes Essentials of Diagnosis, Symptoms and Signs, Diagnostic Studies, Differential Diagonsis, Treatment, and Prognosis Coverage of disorders in both adults and children Practical information on common conditions such as headaches, movement disorders, and central nervous system infections Expert help with ischemicand hemorrhagic stroke, epilepsy, sleeping disorders, dizziness, hearing loss, dementia and memory loss, psychiatric problems, and more Thorough coverage of diagnostic tests More than 100 informative photos and illustrations Updated with the latest findings and developments This second edition will be valuable to anyone who sees patients with neurologic complaints, whether in primary care or the neurology clinic.

Author: Thomas Skripuletz
Publisher: Frontiers Media SA
ISBN: 2889661806
Category : Medical
Languages : en
Pages : 169

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author: A. John Rush Jr.
Publisher: American Psychiatric Pub
ISBN: 1585629065
Category : Medical
Languages : en
Pages : 865

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Book Description
The Handbook of Psychiatric Measures offers a concise summary of key evaluations that you can easily incorporate into your daily practice. The measures will enhance the quality of patient care assisting you, both in diagnosis and assessment of outcomes. Comprising a wide range of methods available for assessing persons with mental health problems, the Handbook contains more than 275 rating methods, from the Abnormal Involuntary Movement Scale to the Zung Self-Rating Depression Scale. In this fully revised edition, more than 40 measures have been added both to the book and to the accompanying CD-ROM. The Handbook features: Thoroughly examined and revised measures that provide the most relevant and timely information for clinicians. New measures that empirically provide better patient evaluation Updated costs, translations, and contact information for each measure This handy compendium includes both diagnostic tools and measures of symptoms, function and quality of life, medication side effects, and other clinically relevant parameters. It focuses on measures that can be most readily used in either clinical practice or research. Most of the measures are designed to improve the reliability and validity of patient assessment over what might be accomplished in a standard clinical interview. The measures also demonstrate that the use of formal measures can improve the collection, synthesis, and reporting of information as compared with the use of unstructured examinations. Seventeen disorder-specific chapters, organized in DSM-IV-TR order, include measures for: Disorders of childhood and adolescence Cognitive disorders Sexual dysfunction Eating disorders Sleep disorders Aggression and much more. The discussion of each measure includes goals, description, practical issues, psychometric properties, and clinical utility, followed by references and suggested readings. This revised edition includes updated measure descriptions, new measure variants and research, and newly selected measures particularly appropriate to the domain of discussion. As a clinical tool, this book Describes how, when, and to what purpose measures are used Points out practical issues to consider in choosing a measure for clinical use Addresses limitations in the use of measures including ethnic, cultural, and socioeconomic factors that influence their interpretation Use of this special resource is further enhanced by a CD-ROM containing the full text of more than 150 of these measures -- an invaluable aid for reference and clinical decision-making.

Author: Geraint Fuller
Publisher: Elsevier Health Sciences
ISBN: 0702048887
Category : Medical
Languages : en
Pages : 143

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Book Description
An introductory textbook of neurology in the Illustrated Colour Text series, making full use of all the usual features of the series - double page spreads, short paragraphs, summary boxes, attractive use of colour etc. - Clear explanation of neurological examination - often found very taxing by students. - Demonstrates how to approach common neurological presentations, such as blackouts and numbness, before moving on to a comprehensive coverage of syndromes and diseases. - Concentrates on the core curriculum which the medical student really needs to know. - Updated management in the light of new evidence and new drugs most notably in Parkinson's disease, epilepsy and multiple sclerosis. - Images, particularly MRI scans, updated with more modern and higher resolution images. - Includes a new double-page spread on Sleep. - Extra material added on giddiness to include the head thrust test and Epley's manoeuvre.

Author: Mehmet Turgut
Publisher: Springer
ISBN: 3319246399
Category : Medical
Languages : en
Pages : 183

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Book Description
This book provides an in-depth review of knowledge of neurobrucellosis, which remains common despite significant improvements in preventive measures, neuroradiological techniques, and treatment methods. The chapters are organized into five sections, the first three of which address cranial and intracranial brucellosis, spinal brucellosis, and brucellosis of the peripheral portions of the nervous system. The fourth section focuses on laboratory studies in neurobrucellosis, and the closing section is devoted to therapy, encompassing both medical approaches and the surgical procedures used to treat the complications associated with brucellosis involving the spine, brain, and peripheral nerves. Despite the impressive efforts to eradicate the disease, brucellosis still poses a great threat in the Mediterranean Basin, where it originated, as well as in South and Central America, the Caribbean, and Africa. Written and edited by leading international authorities in the field, this comprehensive book will be an ideal up-to-date reference for neurosurgeons, neurologists, and specialists in infectious disease who are seeking either basic or more advanced information on the disease and its diagnosis and treatment.

Author: Perminder S. Sachdev
Publisher: Cambridge University Press
ISBN: 1139485229
Category : Medical
Languages : en
Pages :

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Book Description
Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.