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Author: Nils R. Ringertz Publisher: Academic Press ISBN: 1483270092 Category : Science Languages : en Pages : 381
Book Description
Cell Hybrids summarizes the methodology of cell fusion-the fusion of human, animal, and plant cells of different origins to produce cell hybrids-and surveys the main applications and current findings of the hybridization technique. The book opens with a chapter on the history cell hybridization. This is followed by separate chapters on spontaneous cell fusion, virus-induced cell fusion, the cell fusion mechanism, regulation of DNA synthesis and mitosis in heterokaryons and homokaryons, and regulatory events which occur when two cells with different nuclear activity and/or phenotype are fused with each other. Subsequent chapters deal with methods used in preparing various cell fragments and some of their properties and uses in fusion experiments; isolation of growing hybrid cells; chromosome patterns and phenotypic expression in hybrid cells; cell organelles in hybrid cells; analysis of malignancy by cell hybridization. The final chapters discuss the use of somatic cell hybridization to analyze the interaction between a number of viruses and their host cells; and the use of plant cell hybrids.
Author: Nils R. Ringertz Publisher: Academic Press ISBN: 1483270092 Category : Science Languages : en Pages : 381
Book Description
Cell Hybrids summarizes the methodology of cell fusion-the fusion of human, animal, and plant cells of different origins to produce cell hybrids-and surveys the main applications and current findings of the hybridization technique. The book opens with a chapter on the history cell hybridization. This is followed by separate chapters on spontaneous cell fusion, virus-induced cell fusion, the cell fusion mechanism, regulation of DNA synthesis and mitosis in heterokaryons and homokaryons, and regulatory events which occur when two cells with different nuclear activity and/or phenotype are fused with each other. Subsequent chapters deal with methods used in preparing various cell fragments and some of their properties and uses in fusion experiments; isolation of growing hybrid cells; chromosome patterns and phenotypic expression in hybrid cells; cell organelles in hybrid cells; analysis of malignancy by cell hybridization. The final chapters discuss the use of somatic cell hybridization to analyze the interaction between a number of viruses and their host cells; and the use of plant cell hybrids.
Author: Amgad Elgowainy Publisher: Springer ISBN: 9781071614914 Category : Technology & Engineering Languages : en Pages : 0
Book Description
This volume of "Encyclopedia of Sustainability Science and Technology, Second Edition," covers the electrification of vehicles, which is key to a sustainable future of transportation in both light-duty and heavy-duty vehicle sectors to address global concerns of climate change, air pollutant emissions, energy efficiency and energy security. Vehicle electrification includes several existing and emerging technologies and powertrain architectures such as conventional hybrid electric vehicles (HEVs), plug-in hybrids with various electric driving range, short- and long-range battery electric vehicles, as well as hydrogen fuel cell electric vehicles (FCEVs). Electrification will be key to connected autonomous vehicles, which are perceived to improve mobility, increase safety, reduce energy consumption and infrastructure costs, improve productivity, decrease traffic congestion and increase customer satisfaction. While electrification of vehicle technologies is relatively mature, technology improvement and economies of scale are needed to compete against incumbent technologies and to realize their benefits in the marketplace. Significant infrastructure development is needed in the case of hydrogen fuel cell vehicles and to a lesser extent for plug-in electric vehicles. Vehicle efficiency improvement is sought through a combination of several approaches, including weight reduction, engine downsizing, increased engine compression ratio with high octane fuels, and the use of compression ignition engines with low octane fuels. Liquid hydrocarbon fuels are needed in applications where high storage energy density is required such as long-haul class-8 combination heavy-duty trucks. Shared mobility is another emerging concept that enables access to transportation services on an as-needed basis. This approach can enhance accessibility to transportation, decrease number of vehicles on the road, reduce energy use and impact on the environment, reduce cost of transportation and the need for parking, and reduce transportation time between origin and destination. In all, the reader will receive a comprehensive introduction to electric vehicles and technology trends, including energy storage, in light-, medium-, and heavy-duty sectors, as well as the infrastructure development that will be required to realize these benefits for society.
Author: R. G. McKinnell Publisher: Springer Science & Business Media ISBN: 3540382674 Category : Medical Languages : en Pages : 327
Book Description
There is no commonly accepted mechanism to explain differentiation of either normal or neoplastic cells. Despite this fact, the organizers of the 3 rd International Conference on Differentiation recognized that there is much emerging evidence which supports the view that both normal cells and many cancer cells share common differentiative processes. Accordingly, the organizers perceived that clinical scientists and developmental biologists would greatly benefit by together considering differentiation. In that way, developmental biologists would be apprised of recent insights in cancer cell biology and the physician scientist would be updated on events in developmental biology and both would gain new understanding of the cell biology of neoplasia. A specific example may reveal the potential value of developmental biologists interacting with cancer physicians. An example chosen at random suggests that probably any paper included in the symposium volume would serve the purpose. Dr. Stephen Subtelny reviewed recent studies by his laboratory concerning germ cell migration and replication in frog embryos. How might those results interest the cancer scientist? Dr. Subtelny showed that primordial germ cells of a fertile graft will reverse their migratory direction and move into a sterile host. Perhaps in this context it would not be inappropriate to state that the germ cells of the graft metastasized into the host. Germ cells from grafts of a different species will populate the previously sterile host gonad.
Author: Nils R. Ringertz
Author: Nils R. Ringertz
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Author: A. Westerveld
Author: Amgad Elgowainy
Author: Robert Paul Lanza
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Author: R. G. McKinnell
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