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Author: Rene Frenkel Publisher: Elsevier ISBN: 0323153402 Category : Nature Languages : en Pages : 377
Book Description
Carnitine Biosynthesis, Metabolism, and Functions contains the proceedings of the Virginia Lazenby O'Hara Biochemistry Symposium held in Dallas, Texas, from March 31 to April 1, 1979. The papers explore all aspects of carnitine metabolism, including its biosynthesis, regulation, transport, and functions. Comprised of 24 chapters divided into four sections, this book opens with a brief review of the situation which led to the discovery of carnitine as a vitamin and its role in acetylation. The discussion then turns to the chemistry and biosynthesis of carnitine in Neurospora crassa, rat kidney, and humans. The purification of enzymes involved in the conversion of trimethyllysine to trimethylaminobutyrate is also considered. The following chapters examine carnitine transport across the plasma membrane; formation and utilization of isobutyrylcarnitine; regulation of blood carnitine and carnitine acyltransferases in the perinatal period; and inhibitors of carnitine transport and metabolism. The final section is devoted to medical and clinical aspects of carnitine, touching on topics such as the possible causes and effects of carnitine deficiency in humans; carnitine deficiency in cirrhosis; protective effects of L-carnitine on ischemic heart; and changes in carnitine-linked metabolism during ischemia, thermal injury, and shock. This monograph will be a useful resource for biochemists and those interested in the physiological roles of carnitine.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 030905088X Category : Medical Languages : en Pages : 560
Book Description
The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.
Author: Erick J. Vandamme Publisher: John Wiley & Sons ISBN: 3527337342 Category : Science Languages : en Pages : 580
Book Description
Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.
Author: Martin Kohlmeier Publisher: Elsevier ISBN: 0080537898 Category : Medical Languages : en Pages : 841
Book Description
Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source.Key Features* Highly illustrated with relevant chemical structures and metabolic pathways* Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry* First comprehensive work on the subject
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309069491 Category : Medical Languages : en Pages : 530
Book Description
This volume is the newest release in the authoritative series of quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. Dietary Reference Intakes (DRIs) is the newest framework for an expanded approach developed by U.S. and Canadian scientists. This book discusses in detail the role of vitamin C, vitamin E, selenium, and the carotenoids in human physiology and health. For each nutrient the committee presents what is known about how it functions in the human body, which factors may affect how it works, and how the nutrient may be related to chronic disease. Dietary Reference Intakes provides reference intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for different groups based on age and gender, along with a new reference intake, the Tolerable Upper Intake Level (UL), designed to assist an individual in knowing how much is "too much" of a nutrient.
Author: Anne Le Publisher: Springer ISBN: 331977736X Category : Medical Languages : en Pages : 186
Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Author: Klaus Kramer Publisher: CRC Press ISBN: 9780203908174 Category : Health & Fitness Languages : en Pages : 340
Book Description
Promoting scientific support for the plethora of health benefits related to nutrition and medicine, Nutraceuticals in Health and Disease Prevention delivers a comprehensive and scientifically sound overview of the latest research findings in disease prevention, therapy, and enhanced body function in the revolutionary field of nutraceutical technolo
Author: Rene Frenkel Publisher: Elsevier ISBN: 0323153402 Category : Nature Languages : en Pages : 377
Book Description
Carnitine Biosynthesis, Metabolism, and Functions contains the proceedings of the Virginia Lazenby O'Hara Biochemistry Symposium held in Dallas, Texas, from March 31 to April 1, 1979. The papers explore all aspects of carnitine metabolism, including its biosynthesis, regulation, transport, and functions. Comprised of 24 chapters divided into four sections, this book opens with a brief review of the situation which led to the discovery of carnitine as a vitamin and its role in acetylation. The discussion then turns to the chemistry and biosynthesis of carnitine in Neurospora crassa, rat kidney, and humans. The purification of enzymes involved in the conversion of trimethyllysine to trimethylaminobutyrate is also considered. The following chapters examine carnitine transport across the plasma membrane; formation and utilization of isobutyrylcarnitine; regulation of blood carnitine and carnitine acyltransferases in the perinatal period; and inhibitors of carnitine transport and metabolism. The final section is devoted to medical and clinical aspects of carnitine, touching on topics such as the possible causes and effects of carnitine deficiency in humans; carnitine deficiency in cirrhosis; protective effects of L-carnitine on ischemic heart; and changes in carnitine-linked metabolism during ischemia, thermal injury, and shock. This monograph will be a useful resource for biochemists and those interested in the physiological roles of carnitine.
Author: J.C. Kader Publisher: Springer Science & Business Media ISBN: 9401583943 Category : Science Languages : en Pages : 598
Book Description
A collection of papers that comprehensively describe the major areas of research on lipid metabolism of plants. State-of-the-art knowledge about research on fatty acid and glycerolipid biosynthesis, isoprenoid metabolism, membrane structure and organization, lipid oxidation and degradation, lipids as intracellular and extracellular messengers, lipids and environment, oil seeds and gene technology is reviewed. The different topics covered show that modern tools of plant cellular and molecular biology, as well as molecular genetics, have been recently used to characterize several key enzymes of plant lipid metabolism (in particular, desaturases, thioesterases, fatty acid synthetase) and to isolate corresponding cDNAs and genomic clones, allowing the use of genetic engineering methods to modify the composition of membranes or storage lipids. These findings open fascinating perspectives, both for establishing the roles of lipids in membrane function and intracellular signalling and for adapting the composition of seed oil to the industrial needs. This book will be a good reference source for research scientists, advanced students and industrialists wishing to follow the considerable progress made in recent years on plant lipid metabolism and to envision the new opportunities offered by genetic engineering for the development of novel oil seeds.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309172764 Category : Medical Languages : en Pages : 303
Book Description
The activities of the Food and Nutrition Board's Committee on Military Nutrition Research (CMNR, the committee) have been supported since 1994 by grant DAMD17-94-J-4046 from the U.S. Army Medical Research and Materiel Command (USAMRMC). This report fulfills the final reporting requirement of the grant, and presents a summary of activities for the grant period from December 1, 1994 through May 31, 1999. During this grant period, the CMNR has met from three to six times each year in response to issues that are brought to the committee through the Military Nutrition and Biochemistry Division of the U.S. Army Research Institute of Environmental Medicine at Natick, Massachusetts, and the Military Operational Medicine Program of USAMRMC at Fort Detrick, Maryland. The CMNR has submitted five workshop reports (plus two preliminary reports), including one that is a joint project with the Subcommittee on Body Composition, Nutrition, and Health of Military Women; three letter reports, and one brief report, all with recommendations, to the Commander, U.S. Army Medical Research and Materiel Command, since September 1995 and has a brief report currently in preparation. These reports are summarized in the following activity report with synopses of additional topics for which reports were deferred pending completion of military research in progress. This activity report includes as appendixes the conclusions and recommendations from the nine reports and has been prepared in a fashion to allow rapid access to committee recommendations on the topics covered over the time period.
Author: Rene Frenkel
Author: Institute of Medicine
Author: Erick J. Vandamme
Author: Martin Kohlmeier
Author: Institute of Medicine
Author: Anne Le
Author: Klaus Kramer
Author: Rene Frenkel
Author: J.C. Kader
Author: Institute of Medicine
Author: J. Gordon Betts