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Callosal Agenesis

Callosal Agenesis PDF Author: Maryse Lassone
Publisher: Springer Science & Business Media
ISBN: 1461304873
Category : Medical
Languages : en
Pages : 304

Book Description
This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei! in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of the corpus callosum. Since this seminal work, the bulk of neuropsychological research on callosal agenesis has focused on the particulars of interhemispheric transfer and integration. An ever-growing literature has emerged on the subject, attempting to specify the extent and limits of neural plasticity in a nervous system that has evolved in the absence of the most important interhemispheric pathway. Whilst callosal agenesis proves to be an excellent model of cerebral plasticity, it has to be pointed out that this anomaly is often associated with other malformations and neurological diseases that may result in different degrees of mental retardation or other cognitive and sensorimotor deficits. In this context, neurological research on callosal agenesis has concentrated on the description of various syndromes associated with this pathology as well as on the attempt to specify its neurobehavioral manifestations.

Callosal Agenesis

Callosal Agenesis PDF Author: Maryse Lassone
Publisher: Springer Science & Business Media
ISBN: 1461304873
Category : Medical
Languages : en
Pages : 304

Book Description
This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei! in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of the corpus callosum. Since this seminal work, the bulk of neuropsychological research on callosal agenesis has focused on the particulars of interhemispheric transfer and integration. An ever-growing literature has emerged on the subject, attempting to specify the extent and limits of neural plasticity in a nervous system that has evolved in the absence of the most important interhemispheric pathway. Whilst callosal agenesis proves to be an excellent model of cerebral plasticity, it has to be pointed out that this anomaly is often associated with other malformations and neurological diseases that may result in different degrees of mental retardation or other cognitive and sensorimotor deficits. In this context, neurological research on callosal agenesis has concentrated on the description of various syndromes associated with this pathology as well as on the attempt to specify its neurobehavioral manifestations.

Structure and Function of Cerebral Commissures

Structure and Function of Cerebral Commissures PDF Author: I. Steele Russell
Publisher:
ISBN: 9780333234105
Category : Anterior commissure
Languages : en
Pages : 502

Book Description


Micro-, Meso- and Macro-Connectomics of the Brain

Micro-, Meso- and Macro-Connectomics of the Brain PDF Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173

Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

Pediatric Neurology

Pediatric Neurology PDF Author: Ingrid Gamstorp
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 404

Book Description


Atlas of Clinical Neurology E-Book

Atlas of Clinical Neurology E-Book PDF Author: G. David Perkin
Publisher: Elsevier Health Sciences
ISBN: 1437737811
Category : Medical
Languages : en
Pages : 467

Book Description
Atlas of Clinical Neurology, by David Perkin, Douglas C. Miller, Russell Lane, Maneesh C. Patel, and Fred H. Hochberg, delivers the most powerful, clinically oriented image collection of any reference in your specialty - to help you accurately diagnose any condition you see in practice! Approximately 2,000 large, high-quality images – 1,000 in full color - capture the characteristic physical examination and imaging findings of every type of neurological disorder. All of the diagnostic imaging studies have been updated to reflect the dramatic advances in neuroimaging. Updates throughout include a brand-new chapter on myopathies and myasthenia, expanded coverage of epilepsy, and an entire chapter devoted to extrapyramidal disorders. The result is the ultimate diagnostic resource in neurology! Find a perfect match for your clinical findings with the aid of the most powerful, clinically oriented image collection found in any neurology atlas: 2,000 illustrations, 1,000 in full color! Interpret the findings from the latest neuroimaging techniques with the aid of thoroughly updated images representing the most recent advances. Effectively overcome difficult diagnostic challenges with a brand-new chapter on myopathies and myasthenia, expanded coverage of epilepsy, and an entire chapter devoted to extrapyramidal disorders.

Pediatric Neuro-Ophthalmology

Pediatric Neuro-Ophthalmology PDF Author: Michael C. Brodsky
Publisher: Springer Science & Business Media
ISBN: 1461384575
Category : Medical
Languages : en
Pages : 692

Book Description
Pediatric Neuroophthalmology details the diagnostic criteria, current concepts of pathogenesis, neuroradiological correlates, and clinical management of a large group of neuroophthalmic disorders that present in childhood. Surprisingly distinct from neuroophthalmic disorders afflicting adults, this set of diseases falls between the cracks of most ophthalmology training, and thus, warrants a practical, clinical guide for the practitioner in ophthalmology - the neuroophthalmologist, pediatric ophthalmologist, general ophthalmologist - as well as neurologists and for residents. The authors, leading pediatric ophthalmologists, have taken this difficult subject matter and developed an accessible, user-friendly manual with a detailed approach to the recognition, differential diagnosis, and management of pediatric neuroophthalmologic disorders.

The Asymmetrical Brain

The Asymmetrical Brain PDF Author: Kenneth Hugdahl
Publisher: MIT Press
ISBN: 9780262582544
Category : Medical
Languages : en
Pages : 828

Book Description
Research on brain asymmetry, with particular emphasis on findings made possible by recent advances in neuroimaging.

Cerebral Dysgenesis

Cerebral Dysgenesis PDF Author: Harvey B. Sarnat
Publisher: New York : Oxford University Press
ISBN:
Category : Medical
Languages : en
Pages : 504

Book Description
Among physicians responsible for the care of human infants born with a malformed nervous system, there is a compelling need for an accessible synthesis and summary of modern embryological concepts of dysgenesis. This book integrates the morphological, clinical, neurological, genetic, neurophysiological and imaging aspects of cerebral malformation in the context of a lucid embryological explanation. Rather than presenting a catalog of anatomical abnormalities, the text focuses on pathogenesis and clinical aspects. Anatomical appearances are described by imaging in life, while neuropathological features are derived from findings at autopsy. Embryological explanations are identified as documented observation or speculation. Among the topics covered are encephaloceles as a disorder of the primitive streak and node; cerebral hypoplasia as a precocious differentiation of the ependyma before all mitotic generations of the neuroepithelial cells are completed; holosprosencephaly as a disorder of the lamina terminalis; agenesis of the corpus callosum as a failure of programmed glial cell death in the callosal plate in preparation for axonal growth cone passage; subcortical heterotopia as an arrest of late neuroblast migrations due to retraction of radial glial guide fibers from the pial surface of the brain. The literature is exhaustively reviewed and supplemented by the author's own experience. The book is richly illustrated throughout.

Gene Expression to Neurobiology and Behaviour

Gene Expression to Neurobiology and Behaviour PDF Author: Oliver Braddick
Publisher: Elsevier
ISBN: 0444538844
Category : Medical
Languages : en
Pages : 374

Book Description
How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Pediatric Neurology

Pediatric Neurology PDF Author: Kenneth F. Swaiman
Publisher: Elsevier Health Sciences
ISBN: 0323033652
Category : Medical
Languages : en
Pages : 2535

Book Description
This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology