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Author: Luigi Ambrosio Publisher: Elsevier ISBN: 0857096192 Category : Medical Languages : en Pages : 645
Book Description
There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients. After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration. With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice. Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patients Reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery Discusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty
Author: Luigi Ambrosio Publisher: Elsevier ISBN: 0857096192 Category : Medical Languages : en Pages : 645
Book Description
There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients. After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration. With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice. Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patients Reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery Discusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty
Author: Kai-Uwe Lewandrowski Publisher: CRC Press ISBN: 0824756894 Category : Medical Languages : en Pages : 817
Book Description
Advances in Spinal Fusion reveals a new generation of materials and devices for enhanced operations in spinal fusion. This reference showcases emerging research and technologies in areas such as biodegradable implants, drug delivery, stem cell isolation and transfection, cell encapsulation and immobilization, and the design of 2D and 3D scaffolds for cells. It captures a cascade of innovations crucial to increased healing and decreased morbidity in spinal fusion methods and mechanics and addresses current standards in analytical methodology and quality control, it describes the selection of biomaterials for improved biocompatibility, biostability, and structure/function relationships.
Author: R. Gunzburg Publisher: Springer Science & Business Media ISBN: 9783540426875 Category : Medical Languages : en Pages : 148
Book Description
Recent developments in surgical techniques have led to an increased demand for bone stock. Fusion enhancement, bone-void filling in tumor surgery and trauma are only a few examples. Autologous bone can be considered as the most successful bone graft material, and constitutes the accepted 'gold standard', as it combines all the properties required from the bone graft. In this book a 'state of the art in bone substitution for the spine' is presented. The general principles of bone biology and bone healing are outlined, as are recent advances in understanding and influencing bone formation. A variety of substitutes are described and compared.
Author: Sibylle Grad Publisher: Springer Nature ISBN: 3031025806 Category : Science Languages : en Pages : 96
Book Description
Disorders related to the intervertebral disc (IVD) are common causes of morbidity and of severe life quality deterioration. IVD degeneration, although in many cases asymptomatic, is often the origin of painful neck and back diseases. In Western societies IVD related pain and disability account for enormous health care costs as a result of work absenteeism and thus lost production, disability benefits, medical and insurance expenses. Although only a small percentage of patients with disc disorders finally will undergo surgery, spinal surgery has been one of the fastest growing disciplines in the musculoskeletal field in recent years. Nevertheless, current treatment options are still a matter of controversial discussion. In particular, they hardly can restore normal spine biomechanics and prevent degeneration of adjacent tissues. While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP). Recent emphasis has therefore been put in biological ways to regenerate the NP; however, there are a number of obstacles to overcome, considering the exceptional biological and biomechanical environment of this tissue. Different biological approaches such as molecular, gene, and cell based therapies have been investigated and have shown promising results in both in vitro and in vivo studies. Nonetheless, considerable hurdles still exist in their application for IVD regeneration in human patients. The choice of the cells and the choice of the cell carrier suitable for implantation pose major challenges for research and development activities. This lecture recapitulates the basics of IVD structure, function, and degeneration mechanisms. The first part reviews the recent progress in the field of disc and stem cell based regenerative approaches. In the second part, most appropriate biomaterials that have been evaluated as cell or molecule carrier to cope with degenerative disc disease are outlined. The potential and limitations of cell- and biomaterial-based treatment strategies and perspectives for future clinical applications are discussed. Table of Contents: Cell Therapy for Nucleus Pulposus Regeneration / Recent Advances in Biomaterial Based Tissue Engineering for Intervertebral Disc Regeneration
Author: Sibylle Grad Publisher: Morgan & Claypool Publishers ISBN: 1608454649 Category : Medical Languages : en Pages : 96
Book Description
Disorders related to the intervertebral disc (IVD) are common causes of morbidity and of severe life quality deterioration. IVD degeneration, although in many cases asymptomatic, is often the origin of painful neck and back diseases. In Western societies IVD related pain and disability account for enormous health care costs as a result of work absenteeism and thus lost production, disability benefits, medical and insurance expenses. Although only a small percentage of patients with disc disorders finally will undergo surgery, spinal surgery has been one of the fastest growing disciplines in the musculoskeletal field in recent years. Nevertheless, current treatment options are still a matter of controversial discussion. In particular, they hardly can restore normal spine biomechanics and prevent degeneration of adjacent tissues. While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP). Recent emphasis has therefore been put in biological ways to regenerate the NP; however, there are a number of obstacles to overcome, considering the exceptional biological and biomechanical environment of this tissue. Different biological approaches such as molecular, gene, and cell based therapies have been investigated and have shown promising results in both in vitro and in vivo studies. Nonetheless, considerable hurdles still exist in their application for IVD regeneration in human patients. The choice of the cells and the choice of the cell carrier suitable for implantation pose major challenges for research and development activities. This lecture recapitulates the basics of IVD structure, function, and degeneration mechanisms. The first part reviews the recent progress in the field of disc and stem cell based regenerative approaches. In the second part, most appropriate biomaterials that have been evaluated as cell or molecule carrier to cope with degenerative disc disease are outlined. The potential and limitations of cell- and biomaterial-based treatment strategies and perspectives for future clinical applications are discussed. Table of Contents: Cell Therapy for Nucleus Pulposus Regeneration / Recent Advances in Biomaterial Based Tissue Engineering for Intervertebral Disc Regeneration
Author: Dominique G. Poitout Publisher: Springer ISBN: 1848826648 Category : Medical Languages : en Pages : 534
Book Description
With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.
Author: Jason B. Kendall Publisher: Nova Publishers ISBN: 9781600218927 Category : Medical Languages : en Pages : 236
Book Description
Biomaterials serve as synthetic or natural materials used to replace parts of living systems or to function contact with living tissue. Biomaterials are intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ or function of the body. A biomaterial is different from a biological material such as bone that is produced by a biological system. Artificial hips, vascular-stents, artificial pacemakers, and catheters are all made from different biomaterials and comprise different medical devices. This book presents new approaches to biomaterial development including multi-field bone remodelling, novel strategies for conferring antibacterial properties to bone cement, polyacrylonitrile-based biomaterials for enzyme immobilisation and functionalised magnetic nanoparticles for tissue engineering from around the globe.
Author: Kai-Uwe Lewandrowski Publisher: CRC Press ISBN: 9781135525415 Category : Medical Languages : en Pages : 815
Book Description
Advances in Spinal Fusion reveals a new generation of materials and devices for enhanced operations in spinal fusion. This reference showcases emerging research and technologies in areas such as biodegradable implants, drug delivery, stem cell isolation and transfection, cell encapsulation and immobilization, and the design of 2D and 3D scaffolds for cells. It captures a cascade of innovations crucial to increased healing and decreased morbidity in spinal fusion methods and mechanics and addresses current standards in analytical methodology and quality control, it describes the selection of biomaterials for improved biocompatibility, biostability, and structure/function relationships.
Author: Elisa López-Dolado Publisher: Springer Nature ISBN: 3030814009 Category : Medical Languages : en Pages : 327
Book Description
This book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to cure them. The interdisciplinary nature of this book makes it a perfect candidate for the interest of a broad audience, from clinicians working on neural diseases to scientists whose work focuses on the nervous tissue (neuroscientists) and/or materials science. Undergraduate and PhD students can also benefit from the knowledge and discussion included in this book.
Author: Andy H. Choi Publisher: Springer Nature ISBN: 9811674396 Category : Science Languages : en Pages : 279
Book Description
This book is part of a two-part volume book that highlights the latest advances in innovative bioceramics applied in the highly interdisciplinary area referred to as “translational medicine”. This volume predominantly written by surgeons in the fields of craniomaxillofacial, orthopedics, and spinal surgery, examines the translation of innovative bioceramics and bioceramics-based composite from the laboratory to a personalized surgical environment for the repair of damaged and diseased bone tissues. This book also covers the topic of osteoporosis, a skeletal disorder in which the World Health Organization (WHO) has recognized it as a public health emergency due to the high number of subjects who exhibited the disease and the morbidity and mortality related to fractures. The book caters to biomaterials researchers and medical clinicians who are interested in incorporating innovative bioceramics to the above-mentioned applications.
Author: Luigi Ambrosio
Author: Luigi Ambrosio
Author: Kai-Uwe Lewandrowski
Author: R. Gunzburg
Author: Sibylle Grad
Author: Sibylle Grad
Author: Dominique G. Poitout
Author: Jason B. Kendall
Author: Kai-Uwe Lewandrowski
Author: Elisa López-Dolado
Author: Andy H. Choi