The Biology of Degenerative Joint Disease PDF Download

Author: Juerg Hodler
Publisher: Springer Nature
ISBN: 3030712818
Category : Musculoskeletal system
Languages : en
Pages : 293

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Book Description
This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.

Author: C. Wayne McIlwraith
Publisher: Elsevier Health Sciences
ISBN: 1455759694
Category : Medical
Languages : en
Pages : 425

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Book Description
Dr. McIlwraith's Joint Disease in the Horse, 2nd Edition is the only book to give you a full account of equine joint disease, combining a thorough, up-to-date survey of scientific advances with a practical guide to both medical and surgical treatments. With contributions from nationally and internationally recognized pioneers in the field, this groundbreaking text offers an overview of joint structure and function and translates the latest information on basic joint pathobiology into practical application for the clinician. Step-by-step guidance on injection techniques and medications, along with a survey of practical arthroscopic surgery and developments, make it a truly indispensable reference for all equine veterinarians treating sports and racing horses. UNIQUE! Unprecedented, state-of-the-art coverage of the pathology, pathogenesis, and clinical diagnosis of traumatic and degenerative joint disease, so you stay in the know. Section on general principles of joint pathobiology provides the background to evaluate and interpret the diagnostic and surgical aspects of disease. Explores treatments for traumatic arthritis and osteoarthritis and other joint entities, offering a broad range of options and up-to-date recommendations for problematic decisions. Addresses recent advances and results in arthroscopic surgery for the acute injury and results including fragment removal, fragment fixation, and synovectomy. Discussion of current research provides insight for difficult cases and calls out the directions in which future arthritis research is headed. More than 325 photographs and line drawings help engage and guide you through procedures and treatments. NEW! Full color throughout with new artwork and a range of new images including radiographs showing both the normal and the disease progression. NEW! Practical step-by-step approach demonstrates the authors' preferred injections methods and shows underlying anatomic correlations. NEW and UPDATED! Restructured and substantially revised to emphasize treatment options, making it a practical, concise, and accessible reference and text. NEW! All-new chapters on drugs and new biological therapies, including stem cells, IRAP, and PRP and thoroughly updated coverage of HA and corticosteroids. NEW! Covers advanced imaging, giving you the latest information available. NEW! Expert advice from Dr. McIlwraith, three new co-editors, and new contributors - all distinguished specialists in the field of joint disease in the horse. Lameness and surgical clinicians describe how to approach the various, specific disease conditions. Equine specific radiologists provide their opinions on the best imaging techniques for defining the disease and making interpretations.

Author: Leon Sokoloff
Publisher:
ISBN: 9780835772389
Category :
Languages : en
Pages : 174

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Book Description

Author: David T. Felson
Publisher: John Wiley & Sons
ISBN: 9780470930557
Category : Medical
Languages : en
Pages : 320

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Book Description
An authoritative investigation of the sources andtreatment of osteoarthritic joint pain Millions of people throughout the world suffer from osteoarthritis (OA)—a medical condition causing its sufferers excruciating pain that is often disabling. This is the first book to offer clinicians an in-depth understanding of the biological sources of osteoarthritic pain and how they can be treated. Here, a team of leading international authorities has contributed state-of-the-art information on: The Neuroscience of Articular Pain—spinal and peripheral mechanisms of joint pain; experimental models for the study of osteoarthritic pain; inflammatory mediators and nociception in arthritis; phantoms in rheumatology; and more Osteoarthritis and Pain—joint mechanisms and neuromuscular aspects of OA; bone pain and pressure in OA joints; structural correlates of OA pain; and more Treatment of Osteoarthritic Pain—general approaches to treatment; treatments targeting pain receptors; treatments targeting biomechanical abnormalities; and treatments targeting inflammation Whether you're a medical professional, researcher, student, or a generalist or specialist focusing on pain or arthritis, this is your one-stop reference for understanding and treating joint pain in osteoarthritis.

Author: Gene G. Hunder
Publisher:
ISBN:
Category : Family & Relationships
Languages : en
Pages : 208

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Book Description
Covers the causes and symptoms of arthritis; offers tips on pain control, diet, and exercise; and describes such treatment options as medications, surgical procedures, and alternative therapies.

Author: Edward F. McCarthy
Publisher: Cambridge University Press
ISBN: 1107041236
Category : Medical
Languages : en
Pages : 385

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Book Description
Fully updated new edition covering all aspects of bone and joint diseases in one easily readable volume. Color illustrations throughout.

Author: William E. G. Thomas
Publisher: Oxford University Press
ISBN: 0199665540
Category : Medical
Languages : en
Pages : 849

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Book Description
A definitive, accessible, and reliable resource which provides a solid foundation of the knowledge and basic science needed to hone all of the core surgical skills used in surgical settings. Presented in a clear and accessible way it addresses the cross-specialty aspects of surgery applicable to all trainees.

Author: Lucas G. Chase
Publisher: Springer Science & Business Media
ISBN: 1627032002
Category : Science
Languages : en
Pages : 458

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Book Description
Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Author: James Alan Rand
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 488

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Book Description
This comprehensive reference on total knee arthroplasty describes all surgical techniques and prosthetic designs for primary and revision arthroplasty, discusses every aspect of patient selection, preoperative planning, and intraoperative and postoperative care.

Author: Felix Bronner
Publisher: Springer Science & Business Media
ISBN: 1846287014
Category : Medical
Languages : en
Pages : 220

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Book Description
The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on genetics and on newer viewpoints and approaches, exemplified by the possible effect of subchondral bone on osteoarthritis, gives a wider viewpoint to the reader and may enable novel approaches to solving a clinical problem.