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Bioinformatics in MicroRNA Research

Bioinformatics in MicroRNA Research PDF Author: Jingshan Huang
Publisher: Humana Press
ISBN: 9781493970445
Category : Science
Languages : en
Pages : 285

Book Description
This thorough volume provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target genes, miR regulation mechanisms, miR functions performed in various human diseases, and miR databases/knowledgebases. Without prior knowledge of the area of study, computational biologists, computer scientists, bioinformaticians, bench biologists, as well as clinical investigators will find it easy to follow the techniques in this collection. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that ensures successful results. Accessible and practical, Bioinformatics in MicroRNA Research functions as an ideal guide for researchers of all backgrounds to explore this vital area of study.

Bioinformatics in MicroRNA Research

Bioinformatics in MicroRNA Research PDF Author: Jingshan Huang
Publisher: Humana Press
ISBN: 9781493970445
Category : Science
Languages : en
Pages : 285

Book Description
This thorough volume provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target genes, miR regulation mechanisms, miR functions performed in various human diseases, and miR databases/knowledgebases. Without prior knowledge of the area of study, computational biologists, computer scientists, bioinformaticians, bench biologists, as well as clinical investigators will find it easy to follow the techniques in this collection. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that ensures successful results. Accessible and practical, Bioinformatics in MicroRNA Research functions as an ideal guide for researchers of all backgrounds to explore this vital area of study.

MicroRNA Profiling in Cancer

MicroRNA Profiling in Cancer PDF Author: Yuriy Gusev
Publisher: CRC Press
ISBN: 0429533721
Category : Medical
Languages : en
Pages : 273

Book Description
This book presents current advances in the emerging interdisciplinary field of microRNA research of human cancers from a unique perspective of quantitative sciences: bioinformatics, computational and systems biology, and mathematical modeling. This volume contains adaptations and critical reviews of recent state-of-the-art studies, ranging from technological advances in microRNA detection and profiling, clinically oriented microRNA profiling in several human cancers, to a systems biology analysis of global patterns of microRNA regulation of signaling and metabolic pathways. Interactions with transcription factor regulatory networks and mathematical modeling of microRNA regulation are also discussed.

Bioinformatics in MicroRNA Research

Bioinformatics in MicroRNA Research PDF Author: Jingshan Huang
Publisher: Humana
ISBN: 9781493983766
Category : Science
Languages : en
Pages : 285

Book Description
This thorough volume provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target genes, miR regulation mechanisms, miR functions performed in various human diseases, and miR databases/knowledgebases. Without prior knowledge of the area of study, computational biologists, computer scientists, bioinformaticians, bench biologists, as well as clinical investigators will find it easy to follow the techniques in this collection. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that ensures successful results. Accessible and practical, Bioinformatics in MicroRNA Research functions as an ideal guide for researchers of all backgrounds to explore this vital area of study.

MicroRNA Cancer Regulation

MicroRNA Cancer Regulation PDF Author: Ulf Schmitz
Publisher: Springer Science & Business Media
ISBN: 9400755902
Category : Medical
Languages : en
Pages : 352

Book Description
This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with cancer microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.

MiRNomics

MiRNomics PDF Author: Malik Yousef
Publisher:
ISBN: 9781627037488
Category : RNA
Languages : en
Pages : 333

Book Description
In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective. These include methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, miRNomics: MicroRNA Biology and Computational Analysis seeks to aid scientists in the further study into miRNA research and statistics.

Advances in Bioinformatics

Advances in Bioinformatics PDF Author: Vijai Singh
Publisher: Springer Nature
ISBN: 9813361913
Category : Science
Languages : en
Pages : 446

Book Description
This book presents the latest developments in bioinformatics, highlighting the importance of bioinformatics in genomics, transcriptomics, metabolism and cheminformatics analysis, as well as in drug discovery and development. It covers tools, data mining and analysis, protein analysis, computational vaccine, and drug design. Covering cheminformatics, computational evolutionary biology and the role of next-generation sequencing and neural network analysis, it also discusses the use of bioinformatics tools in the development of precision medicine. This book offers a valuable source of information for not only beginners in bioinformatics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in many areas.

MiRNomics

MiRNomics PDF Author: Jens Allmer
Publisher:
ISBN: 9781071611708
Category : MicroRNA
Languages : en
Pages : 442

Book Description
This second edition presents an up-to-date overview of the current state-of-the-art protocols and aims to put the miRNomics into a broader perspective. Chapters detail methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, the miRNomics second edition chapters include introductions to their respective topics, application details for both the expert and non-expert reader and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, miRNomics: MicroRNA Biology and Computational Analysis, Second Edition ensures successful results in the further study of this vital field.

Next Generation Sequencing

Next Generation Sequencing PDF Author: Jerzy Kulski
Publisher: BoD – Books on Demand
ISBN: 9535122401
Category : Medical
Languages : en
Pages : 466

Book Description
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.

MicroRNA in Human Malignancies

MicroRNA in Human Malignancies PDF Author: Massimo Negrini
Publisher: Academic Press
ISBN: 0128232749
Category : Science
Languages : en
Pages : 434

Book Description
MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and opportunities of miRNAs in therapeutics. Chapters on diseases include content on disease-related pathophysiology, as well as diagnostic, prognostic and predictive value. This book is an essential reference for students entering the field, as well as researchers and investigators. Provides fundamental and translational chapters that facilitate the acquisition of knowledge needed to design and perform innovative miRNA-related research studies Synthesizes current research, with a critical review on the field Offers in-depth research by leading experts in the field

Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance PDF Author: Peter Igaz
Publisher: Springer
ISBN: 3034809557
Category : Medical
Languages : en
Pages : 292

Book Description
MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.