Biochip Technology PDF Download

Author: Jing Cheng
Publisher: CRC Press
ISBN: 0203305043
Category : Science
Languages : en
Pages : 453

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Book Description
Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.

Author: Wan-Li Xing
Publisher: Springer Science & Business Media
ISBN: 0387255850
Category : Technology & Engineering
Languages : en
Pages : 355

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Book Description
Frontiers in Biochip Technology Dr. Wan-Li Xing and Dr. Jing Cheng Frontiers in Biochip Technology serves as an essential collection of new research in the field of biochip technology. This comprehensive collection covers emerging technologies and cutting –edge research in the field of biochip technology, with all chapters written by the international stars of this evolving field. Key topics and current trends in biochip technology covered include: -microarray technology and its applications - microfluidics - drug discovery - detection technology - lab-on-chip technology and bioinformatics. Frontiers in Biochip Technology is an important volume for all biotechnologists, bioengineers, genetic engineers, pharmacological researchers, and general bench researchers who want to be up-to-date on the latest advances in the rapidly growing field of biochip technology. The Editors: Dr. Wan-Li Xing, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China Dr. Xing is a Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, and also serves as the Executive Deputy Director at NERCBBT, CapitalBio Corporation, a world-leader in biochip research. Dr. Xing has published widely and obtained many patents and applications. Dr. Jing Cheng, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China Dr. Jing Cheng is the Cheung Kong Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, the Director of NERCBBT and CEO & CTO of CapitalBio. Dr. Cheng developed the world’s first system of laboratory-on-a-chip in 1998; this work was featured in the front-cover story of the June 1998 issue of Nature Biotechnology and cited as the breakthrough of the year by Science in the same year. He has been awarded Nanogen’s most prestigious award Nano Grant, Distinguished Achievement Award for Overseas Chinese Scholars Returned, China’s Science & Technology Award for Outstanding Youth, and Qiushi Technology Transfer Award for Outstanding Youth. Dr. Cheng has published over 90 peer-reviewed papers. In addition, he has obtained over 60 European and U.S. patents and applications.

Author: Wan-Li Xing
Publisher: Springer Science & Business Media
ISBN: 3662050927
Category : Science
Languages : en
Pages : 152

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Book Description
This book brings together contributions from internationally renowned experts in the biochip field. The authors present not only their latest research work, but also discuss current trends in biochip technology. Specific topics range from microarray technology and its applications to lab-on-a-chip technology.

Author: Mark Schena
Publisher: Eaton Publishing Company/Biotechniques Books
ISBN:
Category : Medical
Languages : en
Pages : 352

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Book Description
Technology standards for microarray research (M. Schena, R. W. Davis). Microfluidic technologies and instrumentation for printing DNA microarrays (Don Rose). Novel microarray printing and detection technologies (M. L. Mace Júnior, J. Montagu, Stanley D. Rose, G. McGuinness). A systems approach to fabricating and analyzing DNA microarrayss (J. Worley, K. Bechtol, S. Penn, D. Roach, D. hanzel, M. Trounstine, D. B.). The flow-thru chip: a three-dimensional biochip platform (A. Stell, M. Torres, J. Hartwell, Yong-Yi Yu, Nan Ting, G. Hoke, H. Yang). Large-scale genomic analysis using affymetrix genechip probe arrays (J. A. Warrington, S. Dee, M. Trulson). Technology and applications of gene expression microarrays (E. Evertsz, P. Starink, R. Gupta, D. Watson). Information processing issues and solutions associated with microarray technology (Y.-X. Zhou, P. Kalocsai, J.-Y. Chen, S. Shams). Microarray tools, kits, reagents, and services (T. Martinsky, P. Haje). Micromax: a highly sensitive system for differential gene expression on microarrays (K. Adler, J. Broadbent, R. Garlick, R. Joseph, A. Khimani, A. Mikulskis, P. Rapiejko, J. Killian). Production of microarrays on porous substrates using noncontact piezoelectric dispensing (D. Englert). Arrayed primer extension on the DNA chip: method and applications (N. Tonisson, A. Kurg, E. Lõhmussaar, A. Metspalu). Overview of a microarray scanner: design essentials for an integrated acquisition and analysis platform (T. Basarsky, D. Verdnik, J. Ye Zhai, D. Wellis). Selected supplier list. Index.

Author: Krishnendu Chakrabarty
Publisher: CRC Press
ISBN: 1420008307
Category : Technology & Engineering
Languages : en
Pages : 228

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Book Description
Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

Author: Kewal K. Jain
Publisher: Springer Science & Business Media
ISBN: 1441907696
Category : Medical
Languages : en
Pages : 443

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Book Description
Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. Basic technologies for personalized medicine, of which molecular diagnostics has the biggest share, are mentioned briefly and appropriate references are given for further information. Commercial aspects are discussed briefly in a chapter and detailed analysis of markets and companies involved in personalized medicine is presented in a special report on this topic. There is increasing interest in personalized medicine. Considerable advances have taken place in molecular biology and biotechnology to make personalized medicine a viable option, but some misconceptions still exist, both in the academic and commercial sectors. There is lack of a suitable source of information that provides both the fundamentals as well as applications of personalized medicine. As the latest version of the first monograph on personalized medicine published in 1998, this volume, Textbook of Personalized Medicine, summarizes the author’s efforts during the past decade, as well as reviews selected studies done during this period in a readable format for the physicians and scientists. It is hoped that physicians, pharmacists, scientists and interested lay readers with basic scientific knowledge will find this book useful.

Author: Andrew Carmen
Publisher: CRC Press
ISBN: 1420015605
Category : Medical
Languages : en
Pages : 420

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Book Description
In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as bioc

Author: Giampaolo Zuccheri
Publisher: IWA Publishing
ISBN: 1780401086
Category : Science
Languages : en
Pages : 314

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Book Description
Detection of Pathogens in Water Using Micro and Nano-Technology aims to promote the uptake of innovative micro and nano-technological approaches towards the development of an integrated, cost-effective nano-biological sensor useful for security and environmental assays. The book describes the concerted efforts of a large European research project and the achievements of additional leading research groups. The reported knowledge and expertise should support in the innovation and integration of often separated unitary processes. Sampling, cell lysis and DNA/RNA extraction, DNA hybridisation detection micro- and nanosensors, microfluidics, together also with computational modelling and risk assessment can be integrated in the framework of the current and evolving European regulations and needs. The development and uptake of molecular methods is revolutionizing the field of waterborne pathogens detection, commonly performed with time-consuming cultural methods. The molecular detection methods are enabling the development of integrated instruments based on biosensor that will ultimately automate the full pathway of the microbiological analysis of water. Editors: Giampaolo Zuccheri, University of Bologna, Italy and Nikolaos Asproulis, Cranfield University, UK

Author: Jürgen Popp
Publisher: John Wiley & Sons
ISBN: 3527410481
Category : Science
Languages : en
Pages : 1187

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Book Description
This new handbook covers the world of biophotonics not only geographically -- with the editors coming from different continents -- but also in terms of content, since the authors come from the whole spectrum of biophotonic basic and applied research. Designed to set the standard for the scientific community, these three volumes break new ground by providing readers with the physics basics as well as the biological and medical background, together with detailed reports on recent technical advances. The Handbook also adopts an application-related approach, starting with the application and then citing the various tools to solve the scientific task, making it of particular value to medical doctors. Divided into several sections, the first part offers introductory chapters on the different fields of research, with subsequent parts focusing on the applications and techniques in various fields of industry and research. The result is a handy source for scientists seeking the basics in a condensed form, and equally a reference for quickly gathering the knowledge from neighboring disciplines. Absolutely invaluable for biophotonic scientists in their daily work.

Author: Christopher R. Fee
Publisher: Bloomsbury Publishing USA
ISBN:
Category : History
Languages : en
Pages : 668

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Book Description
This up-to-date introduction to the complex world of conspiracies and conspiracy theories provides insight into why millions of people are so ready to believe the worst about our political, legal, religious, and financial institutions. Unsupported theories provide simple explanations for catastrophes that are otherwise difficult to understand, from the U.S. Civil War to the Stock Market Crash of 1929 to the terrorist attacks on the World Trade Center in New York. Ideas about shadowy networks that operate behind a cloak of secrecy, including real organizations like the CIA and the Mafia and imagined ones like the Illuminati, additionally provide a way for people to criticize prevailing political and economic arrangements, while for society's disadvantaged and forgotten groups, conspiracy theories make their suffering and alienation comprehensible and provide a focal point for their economic or political frustrations. These volumes detail the highly controversial and influential phenomena of conspiracies and conspiracy theories in American society. Through interpretive essays and factual accounts of various people, organizations, and ideas, the reader will gain a much greater appreciation for a set of beliefs about political scheming, covert intelligence gathering, and criminal rings that has held its grip on the minds of millions of American citizens and encouraged them to believe that the conspiracies may run deeper, and with a global reach.