Author: Xiaohong Wang Publisher: Nova Science Publishers ISBN: 9781634829571 Category : Artificial organs Languages : en Pages : 0
Book Description
This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.
Author: Dimitrios Stamatialis Publisher: World Scientific ISBN: 9813223987 Category : Technology & Engineering Languages : en Pages : 346
Book Description
This book focusses on the development of biomedical membranes and their applications for (bio)artificial organs. It covers the state of art and main challenges for applying synthetic membranes in these organs. It also highlights the importance of accomplishing an integration of engineering with biology and medicine to understand and manage the scientific, industrial, clinical and ethical aspects of these organs.The compendium consists of 11 chapters, written by world renowned experts in the fields of membrane technology, biomaterials science and technology, cell biology, medicine and engineering. Every chapter describes the clinical needs and the materials, membranes, and concepts required for the successful development of the (bio)artificial organs.This text is suitable for undergraduate and graduate students in biomedical engineering, materials science and membrane science and technology, as well as, for professionals and researchers working in these fields.
Author: Loredana De Bartolo Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110390884 Category : Medical Languages : en Pages : 302
Book Description
Membrane processes today play a signifi cant role in the replacement therapy for acute and chronic organ failure diseases. Current extracorporeal blood purifi cation and oxygenation devices employ membranes acting as selective barriers for the removal of endogeneous and exogeneous toxins and for gas exchange, respectively. Additionally, membrane technology offers new interesting opportunities for the design of bioartificial livers, pancreas, kidneys, lungs etc. This book reviews the latest developments in membrane systems for bioartificial organs and regenerative medicine, investigates how membrane technology can improve the quality and efficiency of biomedical devices, and highlights the design procedures for membrane materials covering the preparation, characterization, and sterilization steps as well as transport phenomena. The different strategies pursued for the development of membrane bioartifi cial organs, including crucial issues related to blood/cell-membrane interactions are described with the aim of opening new and exciting frontiers in the coming decades. The book is a valuable tool for tissue engineers, clinicians, biomaterials scientists, membranologists as well as biologists and biotechnologists. It is also a source of reference for students, academic and industrial researchers in the topic of biotechnology, biomedical engineering, materials science and medicine.
Author: Aleš Prokop Publisher: ISBN: Category : Medical Languages : en Pages : 512
Book Description
This volume addresses the current status and future possibilities of bioartificial organs, highlighting biomedical applications. Contemporary and emerging approaches to the development of bioartificial organs are explored. Presentations are interdisciplinary: scientists from the fields of materials and polymer sciences, bioprocess engineering and clinical medicine who do not normally interact at a single conference were brought together to deliberate. Emphasis is placed on the pancreas, liver, skin and bone, although other tissues are also covered.
Author: David Hunkeler Publisher: ISBN: Category : Medical Languages : en Pages : 518
Book Description
The 38 papers of this volume were first presented at the third Bioartificial Organs Conference, held in October 2000 in Davos, Switzerland. Many of the international group of contributors present topics that highlight the interdisciplinary characteristics of the field where biotechnology, medicine, and materials science meet. The papers are grouped by topics, among them: tissue sourcing, immunoisolation, encapsulation, purification and compatibility, islet and bioartificial pancreas, bioartificial kidney and liver, blood substitutes, and tissue engineering. Annotation copyrighted by Book News, Inc., Portland, OR.
Author: Sangeeta N. Bhatia Publisher: Springer Science & Business Media ISBN: 1461552354 Category : Science Languages : en Pages : 160
Book Description
The Microsystems Series has as its goal the creation of an outstanding set of textbooks, references, and monographs on subjects that span the broad field of microsystems. Exceptional PhD dissertations provide a good starting point for such a series, because, unlike monographs by more senior authors, which must compete with other professional duties for attention, the dissertation becomes the sole focus of the author until it is completed. Conversion to book form is then a streamlined process, with final editing and book production completed within a few months. Thus we are able to bring important and timely material into book form at a pace which tracks this rapidly developing field. Our first four books in the series were drawn from the more physics-oriented side of the microsystems field, including such diverse subjects as computer-aided design, atomic-force microscopy, and ultrasonic motion detection. Now, with Sangeeta Bhatia's work, we enter the realm of biology. Her use of artifically structured substrates to encourage the liver cells to form orderly assemblies is a fine example of how microfabrication technology can contribute to cell biology and medicine. I am pleased to be able to add this very new and very interesting work to the Microsystems Series. Stephen D. Senturia Cambridge MA Microfabrication in Tissue Engineering and Bioartificial Organs Foreword One of the emerging applications of microsystems technology in biology and medicine is in the field of tissue engineering and artificial organs. In order to function, cells need to receive proper signals from their environment.
Author: David Hunkeler Publisher: ISBN: Category : Medical Languages : en Pages : 440
Book Description
The presentations in this volume, resulting from the 2nd International Conference on Bioartificial Organs, are divided almost equally among medical practitioners and surgeons, materials scientists and engineers; presenters came from industry, academia and governmental organizations. Sections are dedicated to specific diseases and organ replacements, such as the bioartificial pancreas (diabetes). Clinical trials on the bioartificial liver and skin are presented as are new developments in the craniofacial and cartilage areas. There is discussion on tissue sourcing (xeno-and allografts) as well as on the suitability of the proposed xenotransplantation for immunoisolation devices. Advances in genetically modified cells are also highlighted. Sessions on the molecular aspects of rejection prevention, on new biomaterials, and on processing complement the plenary medical- and technology-oriented themes. A panel discussion on scale-up and commercial implementation rounds out the volume.
Author: K. Schügerl Publisher: Springer ISBN: 3540457364 Category : Technology & Engineering Languages : en Pages : 286
Book Description
This special volume "Tools and Applications of Biochemical Engineering Science" is dedicated to Professor Wolf-Dieter Deckwer on the occasion of his 60th bir- day. It was a great pleasure for me to act together with Professor Karl Schtigerl as volume editor and to present here a collection of 11 outstanding review articles written mainly by former students, associates, colleagues and friends of Wolf- Dieter Deckwer. The title of this special volume well reflects the research interests and sci- tific pursuit of Wolf-Dieter Deckwer during his more than 20 years’ work in the area of biochemical engineering, particularly during the last 15 years when he was the head of the Biochemical Engineering Division of GBF (German Nat- nal Research Center for Biotechnology). He has decisively pushed the devel- ment not only of "software tools" ranging from analytical means and mathe- tical models for monitoring and understanding cellular processes to gene expression systems for designing microorganisms, but also of "hardware tools" such as computer control systems, bioreaction and separation devices for eff- tively producing a variety of bioproducts on semi-production scale. New developments in some of these important tools in biochemical engineering are reviewed in articles included in this volume. Wolf-Dieter Deckwer was among the leading biochemical engineers who timely pointed out the necessity of applying these tools in an integrated manner for bioprocess development. By establishing "Integrated Bioprocess Development" as one of the GBF main - search topics as early as 1990 he also actively promoted this idea.
Author: Nihal Vrana Publisher: Woodhead Publishing ISBN: 0081029071 Category : Medical Languages : en Pages : 847
Book Description
Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations
Author: Xiaohong Wang
Author: Dimitrios Stamatialis
Author: Loredana De Bartolo
Author: Aleš Prokop
Author: David Hunkeler
Author: Sangeeta N. Bhatia
Author: 
Author: David Hunkeler
Author: K. Schügerl
Author: Nihal Vrana