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Author: H. Thomas Milhorn Publisher: Springer ISBN: 9783319630397 Category : Medical Languages : en Pages : 354
Book Description
This practical and timely book provides comprehensive, state-of-the-art guidance on how primary care clinicians can best care for patients with substance use disorders. The book covers the major drugs of abuse, as well as the more recent ones, detailing the biology of various addictions and all dimensions of clinical diagnosis and management. It is organized in four parts: (1) The Basics, (2) Psychoactive Substance Dependencies, (3) Diagnosis, Treatment, Recovery, Relapse, and the Family, and (4) Special Groups. Part I, The Basics, consists of an overview, the various definitions of substance dependence, and the pharmacology of addictive substances. Chapter 1, Overview, is an introductory chapter that covers material common to the entire field of substance dependence. Chapter 2 covers the various definitions of substance dependence, and Chapter 3 reviews the pharmacology of addictive substances. Part II, Psychoactive Substance Dependencies, explains the various drug dependencies—alcohol dependence, sedative-hypnotic dependence, opioid dependence, stimulant dependence, nicotine dependence, cannabis dependence, dissociative dependence, inhalant dependence, hallucinogen dependence, and anabolic steroid dependence. Part III addresses diagnosis, treatment, recovery, relapse, and the family. Part IV, Special Groups, discusses substance dependence in women, adolescents, the elderly, ethnic minority groups, co-occurring disorders, LGBT patients, HIV positive patients, and the impaired physician. In addition to primary care physicians, Substance Use Disorders: A Guide for the Primary Care Provider will serve as an invaluable resource to primary care nurse practitioners and physician assistants, as well as medical students, primary care residents, emergency medicine physicians, ASAM and APA certified addictionists and those studying for certification in those specialties, psychiatrists, psychologists, and alcohol/drug counselors.
Author: H. Thomas Milhorn Publisher: Springer ISBN: 9783319630397 Category : Medical Languages : en Pages : 354
Book Description
This practical and timely book provides comprehensive, state-of-the-art guidance on how primary care clinicians can best care for patients with substance use disorders. The book covers the major drugs of abuse, as well as the more recent ones, detailing the biology of various addictions and all dimensions of clinical diagnosis and management. It is organized in four parts: (1) The Basics, (2) Psychoactive Substance Dependencies, (3) Diagnosis, Treatment, Recovery, Relapse, and the Family, and (4) Special Groups. Part I, The Basics, consists of an overview, the various definitions of substance dependence, and the pharmacology of addictive substances. Chapter 1, Overview, is an introductory chapter that covers material common to the entire field of substance dependence. Chapter 2 covers the various definitions of substance dependence, and Chapter 3 reviews the pharmacology of addictive substances. Part II, Psychoactive Substance Dependencies, explains the various drug dependencies—alcohol dependence, sedative-hypnotic dependence, opioid dependence, stimulant dependence, nicotine dependence, cannabis dependence, dissociative dependence, inhalant dependence, hallucinogen dependence, and anabolic steroid dependence. Part III addresses diagnosis, treatment, recovery, relapse, and the family. Part IV, Special Groups, discusses substance dependence in women, adolescents, the elderly, ethnic minority groups, co-occurring disorders, LGBT patients, HIV positive patients, and the impaired physician. In addition to primary care physicians, Substance Use Disorders: A Guide for the Primary Care Provider will serve as an invaluable resource to primary care nurse practitioners and physician assistants, as well as medical students, primary care residents, emergency medicine physicians, ASAM and APA certified addictionists and those studying for certification in those specialties, psychiatrists, psychologists, and alcohol/drug counselors.
Author: Richard L. Miller Publisher: Greenwood ISBN: 0313318077 Category : Health & Fitness Languages : en Pages : 0
Book Description
Draws together information from a variety of sources to list and describe more than 130 addictive drugs, including both natural substances and pharmaceutical products.
Author: Mario Herrera Publisher: Pearson Longman ISBN: 9781447950820 Category : Juvenile Nonfiction Languages : en Pages : 320
Book Description
Share in your pupils' success. Watch them excel in English Big English prepares pupils for the challenges they will find in today's world: *CLIL: because pupils are learning English and so much more *21st Century Skills: because pupils want to get ahead and need to be prepared for the world around them *Assessment for Learning: because confidence leads to success Think BIG Dream BIG BIG ENGLISH
Author: Mario Herrera Publisher: Pearson Longman ISBN: 9781447950790 Category : Juvenile Nonfiction Languages : en Pages : 128
Book Description
This 6 level course in American English aims to make sure that every student has the tools they need to succeed in English with fun topics and activities that motivate students to learn
Author: Mario Herrera (Teacher of English as a foreign language) Publisher: Pearson Longman ISBN: 9781447994503 Category : Foreign Language Study Languages : en Pages : 0
Book Description
The Teacher's Book provides step-by-step Lesson Plans, activities and ideas, a game bank, Pupil's Book and Activity Book audio scripts, Activity Book answer keys, and notes for using the Young Learners' Exams Practice Materials found in the Pupil's Book. Assessment for Learning techniques and ideas for developing 21st Century Skills are contained in each Lesson Plan. Objectives for each class are clearly identified. Guidelines for activities to develop Critical Thinking, Communication, Collaboration and Self Direction. Teaching Tips designed to get the best from students. Ideas for additional games and activities to reinforce learning in a fun way.
Author: Mario Herrera Publisher: Pearson Longman ISBN: 9781447951292 Category : Juvenile Nonfiction Languages : en Pages : 128
Book Description
This 6 level course in American English aims to make sure that every student has the tools they need to succeed in English with fun topics and activities that motivate students to learn
Author: Claudio Toniolo Publisher: John Wiley & Sons ISBN: 9783906390529 Category : Science Languages : en Pages : 726
Book Description
Originally a special issue of Chemistry & Biodiversity, this is an excellent overview of the status of contemporary studies in peptaibiotics, covering aspects ranging from the search for novel bioactive compounds to considerations of their membrane-modifying properties.
Author: Yanyan Li Publisher: Springer ISBN: 1493910108 Category : Medical Languages : en Pages : 113
Book Description
Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located in the tail below and above the ring and/or disulfide bridges connecting the ring and the tail. Lasso peptides are subdivided into three subtypes depending on the absence (class II) or presence of one (class III) or two (class I) disulfide bridges. The lasso topology results in highly compact structures that give to lasso peptides an extraordinary stability towards both protease degradation and denaturing conditions. Lasso peptides are generally receptor antagonists, enzyme inhibitors and/or antibacterial or antiviral (anti-HIV) agents. The lasso scaffold and the associated biological activities shown by lasso peptides on different key targets make them promising molecules with high therapeutic potential. Their application in drug design has been exemplified by the development of an integrin antagonist based on a lasso peptide scaffold. The biosynthesis machinery of lasso peptides is therefore of high biotechnological interest, especially since such highly compact and stable structures have to date revealed inaccessible by peptide synthesis. Lasso peptides are produced from a linear precursor LasA, which undergoes a maturation process involving several steps, in particular cleavage of the leader peptide and cyclization. The post-translational modifications are ensured by a dedicated enzymatic machinery, which is composed of an ATP-dependent cysteine protease (LasB) and a lactam synthetase (LasC) that form an enzymatic complex called lasso synthetase. Microcin J25, produced by Escherichia coli AY25, is the archetype of lasso peptides and the most extensively studied. To date only around forty lasso peptides have been isolated, but genome mining approaches have revealed that they are widely distributed among Proteobacteria and Actinobacteria, particularly in Streptomyces, making available a rich resource of novel lasso peptides and enzyme machineries towards lasso topologies.
Author: H. Thomas Milhorn
Author: H. Thomas Milhorn
Author: Richard L. Miller
Author: Mario Herrera
Author: Mario Herrera
Author: Mario Herrera (Teacher of English as a foreign language)
Author: Mario Herrera
Author: David Cotton
Author: Jennifer Baines
Author: Claudio Toniolo
Author: Yanyan Li