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Beyond the borders: The gates and fences of Neuroimmune interaction

Beyond the borders: The gates and fences of Neuroimmune interaction PDF Author: Javier Velázquez-Moctezuma
Publisher: Frontiers E-books
ISBN: 2889192741
Category : Neuroimmunology
Languages : en
Pages : 120

Book Description
Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro-immune interactions. Brain was shown to be under the continuous surveillance of the immune system, even under basal physiological conditions in the absence of any pathology. Likely, it was found a profuse nervous innervation of lymphoid organs and even of single immune cells. Gates for direct neural immune communication were found both centrally and peripherally. Centrally, the gates, but also the fences, were situated at the brain barriers, the blood-brain barrier and the blood-cerebrospinal fluid barrier, and at the circunventricular organs. Peripherally, the fences constituted the apparent diverse nature of molecules involved in neural and immune signaling; however, time proved that both system were capable of producing the same signaling molecules and also systematically responded to the molecules released by the other system. Therefore, the gates were open for direct neural-immune communication at the peripheral level. This Research Topic aimed to include original reports, reviews and technical reports regarding the description of the gates and fences in neural immune interactions. We intended to provide an extensive view of the mechanisms governing central and peripheral neural-immune interactions, and the role of the borders, the blood-neural barriers, in the regulation of the neural-immune communication.

Beyond the borders: The gates and fences of Neuroimmune interaction

Beyond the borders: The gates and fences of Neuroimmune interaction PDF Author: Javier Velázquez-Moctezuma
Publisher: Frontiers E-books
ISBN: 2889192741
Category : Neuroimmunology
Languages : en
Pages : 120

Book Description
Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro-immune interactions. Brain was shown to be under the continuous surveillance of the immune system, even under basal physiological conditions in the absence of any pathology. Likely, it was found a profuse nervous innervation of lymphoid organs and even of single immune cells. Gates for direct neural immune communication were found both centrally and peripherally. Centrally, the gates, but also the fences, were situated at the brain barriers, the blood-brain barrier and the blood-cerebrospinal fluid barrier, and at the circunventricular organs. Peripherally, the fences constituted the apparent diverse nature of molecules involved in neural and immune signaling; however, time proved that both system were capable of producing the same signaling molecules and also systematically responded to the molecules released by the other system. Therefore, the gates were open for direct neural-immune communication at the peripheral level. This Research Topic aimed to include original reports, reviews and technical reports regarding the description of the gates and fences in neural immune interactions. We intended to provide an extensive view of the mechanisms governing central and peripheral neural-immune interactions, and the role of the borders, the blood-neural barriers, in the regulation of the neural-immune communication.

Nijkamp and Parnham's Principles of Immunopharmacology

Nijkamp and Parnham's Principles of Immunopharmacology PDF Author: Michael J. Parnham
Publisher: Springer Nature
ISBN: 3030108112
Category : Medical
Languages : en
Pages : 888

Book Description
Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Rhetorical Animals

Rhetorical Animals PDF Author: Kristian Bjørkdahl
Publisher: Lexington Books
ISBN: 1498558461
Category : Literary Criticism
Languages : en
Pages : 319

Book Description
For this edited volume, the editors solicited chapters that investigate the place of nonhuman animals in the purview of rhetorical theory; what it would mean to communicate beyond the human community; how rhetoric reveals our "brute roots." In other words, this book investigates themes that enlighten us about likely or possible implications of the animal turn within rhetorical studies. The present book is unique in its focus on the call for nonanthropocentrism in rhetorical studies. Although there have been many hints in recent years that rhetoric is beginning to consider the implications of the animal turn, as yet no other anthology makes this its explicit starting point and sustained objective. Thus, the various contributions to this book promise to further the ongoing debate about what rhetoric might be after it sheds its long-standing humanistic bias.

Cancer Genetics and Psychotherapy

Cancer Genetics and Psychotherapy PDF Author: Parvin Mehdipour
Publisher: Springer
ISBN: 3319645501
Category : Medical
Languages : en
Pages : 1189

Book Description
The aim of this book is to provide the readers with the most comprehensive and latest accounts of research and development in this field by emphasizing on the manner of relation between doctors and cancer patients in direction of improving the patients’ style of life. This book, partly, will deal with psychotherapy by considering cancer patients, benefits, hazards and also social impacts including life style. The social supports as the key and influential paradigms will be challenged as a comparative insight by considering the global unity in order to provide a reasonable model to improve the interaction between cancer and psychological nest. In this book, the real stories of cancer patient will be also provided. The initial insight of sections includes: 1) Brief classifications and key points of clinical and histopatological aspects of each organ. 2) Brief view of genetic alterations in each organ. 3) Therapeutic aspects. 4) Brief classifications and key points of Psychology in cancer. 5) The interactions of clinical aspects with psychological field.

An Evocative Autoethnography of Living Alongside Myalgic Encephalomyelitis (ME)

An Evocative Autoethnography of Living Alongside Myalgic Encephalomyelitis (ME) PDF Author: Orlagh Farrell Delaney
Publisher: Cambridge Scholars Publishing
ISBN: 1527573281
Category : Body, Mind & Spirit
Languages : en
Pages : 277

Book Description
This ground-breaking book explores and explains the day-to-day realities of living long-term with Myalgic Encephalomyelitis (ME). ME is an acquired complex disorder characterised by a variety of symptoms affecting multiple systems of the body. Marked fatigue and weakness, sickness, cognitive dysfunction and symptom flare-up can follow any physical or cognitive exertion. It is estimated that there are 17-24 million sufferers worldwide. The author has lived with moderately severe ME for the last 18 years. Utilising autoethnography as a methodology and drawing on multidisciplinary social science theory, the book tells the story of the author’s own lived experiences of the illness, and how she sought to reimagine a ‘self’ or a life living alongside the illness, that could still be considered a ‘good life’. This autoethnographic book is beautifully and evocatively written. It is a work of scholarship that will be highly accessible to academic and other readers. It is also a comprehensive introduction to autoethnography as a methodology, but it is much more. The images and poetry complement the narrative discussion, and are exemplary as part of an approach that integrates creative work with academic argument. It illuminates the struggles of living with ME and how there can be sanctuary.

Viruses: Essential Agents of Life

Viruses: Essential Agents of Life PDF Author: Günther Witzany
Publisher: Springer Science & Business Media
ISBN: 940074899X
Category : Science
Languages : en
Pages : 432

Book Description
A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.

Proceedings of the 51st Congress of the International Society for Applied Ethology

Proceedings of the 51st Congress of the International Society for Applied Ethology PDF Author: Margit Bak Jensen
Publisher: Brill Wageningen Academic
ISBN: 9789086863112
Category : Animal behavior
Languages : en
Pages : 0

Book Description
Understanding animal behaviour is the overall theme of the 51st Congress of the International Society for Applied Ethology. This abstract book gives an overview of interaction between animals and the environments in which they are kept and to improve animal welfare.

Gastrointestinal Physiology

Gastrointestinal Physiology PDF Author: Menizibeya Osain Welcome
Publisher: Springer
ISBN: 3319910566
Category : Medical
Languages : en
Pages : 1037

Book Description
This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.

Urban Wildlife Conservation

Urban Wildlife Conservation PDF Author: Robert A. McCleery
Publisher: Springer
ISBN: 1489975004
Category : Science
Languages : en
Pages : 408

Book Description
In the past, wildlife living in urban areas were ignored by wildlife professionals and urban planners because cities were perceived as places for people and not for wild animals. Paradoxically, though, many species of wildlife thrive in these built environments. Interactions between humans and wildlife are more frequent in urban areas than any other place on earth and these interactions impact human health, safety and welfare in both positive and negative ways. Although urban wildlife control pest species, pollinate plants and are fun to watch, they also damage property, spread disease and even attack people and pets. In urban areas, the combination of dense human populations, buildings, impermeable surfaces, introduced vegetation, and high concentrations of food, water and pollution alter wildlife populations and communities in ways unseen in more natural environments. For these ecological and practical reasons, researchers and mangers have shown a growing interest in urban wildlife ecology and management. This growing interest in urban wildlife has inspired many studies on the subject that have yet to be synthesized in a cohesive narrative. Urban Wildlife: Theory and Practice fills this void by synthesizing the latest ecological and social knowledge in the subject area into an interdisciplinary and practical text. This volume provides a foundation for the future growth and understanding of urban wildlife ecology and management by: • Clearly defining th e concepts used to study and describe urban wildlife, • Offering a cohesive understanding of the coupled natural and social drivers that shape urban wildlife ecology, • Presenting the patterns and processes of wildlife response to an urbanizing world and explaining the mechanisms behind them and • Proposing means to create physical and social environments that are mutually beneficial for both humans and wildlife.

Phonetics, Theory and Application

Phonetics, Theory and Application PDF Author: William R. Tiffany
Publisher: McGraw-Hill Humanities, Social Sciences & World Languages
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 456

Book Description