Astrocytes, a Kaleidoscope of Diversities, a Pharmacological Horizon PDF Download

Author: Lorenzo Di Cesare Mannelli
Publisher: Frontiers Media SA
ISBN: 2889666840
Category : Science
Languages : en
Pages : 124

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Author: Taylor & Francis Group
Publisher: CRC Press
ISBN: 9780367658441
Category :
Languages : en
Pages : 289

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Book Description
Gap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes. A gap junction channel is formed by the docking of two hemichannels, and each hemichannel is a hexamer of connexins. The field of gap junction channel and hemichannel research has recently exploded and became one of the most active areas of cell biology. Numerous novel approaches and techniques have been developed, but there is no single book dedicated to the unique techniques and protocols employed for the research on these large pore channels. This book fills the gap and focuses on protocols, approaches and reviews of gap junction channels and connexin hemichannels. It will be a useful reference for graduate students, postdoctoral fellows and researchers. Anyone with an interest in gap junction channels and hemichannels will need this summary of state-of-the-art techniques and protocols.

Author: Ronald J. Bradley
Publisher: Elsevier
ISBN: 0080463614
Category : Science
Languages : en
Pages : 357

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Book Description
The book presents a basis for the interaction of the brain and nervous system with painting, music and literature, and a discussion of art from multiple facets – such as anatomy, migraine, illusion and evolutionary biology. The book explores several aspects of the neurobiology of painting, including evolutionary neurobiology, sensation vs. perception, the visual brain and how the mind works, and also explores the affects of brain disorders and trauma on artist, with a concluding chapter on Frida Kahlo and the spinal cord injury that influenced her painting.

Author: Alexei Verkhratsky
Publisher: John Wiley & Sons
ISBN: 9780470513071
Category : Medical
Languages : en
Pages : 230

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Book Description
"This volume is a very valuable and much needed contribution." –Quarterly Review of Biology AT LAST - A comprehensive, accessible textbook on glial neurobiology! Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease. Features of this book: an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

Author: Ronald Comer
Publisher: John Wiley & Sons
ISBN: 0471385190
Category : Psychology
Languages : en
Pages : 1478

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Book Description
This exciting new textbook for introductory psychology helps to open students’ minds to the idea that psychology is all around us. Authors RON COMER and LIZ GOULD encourage students to examine what they know about human behaviour and how they know it; and open them up to an appreciation of psychology outside of the classroom. Psychology Around Us helps students see the big picture by stressing the interconnected nature of psychological science. Almost every chapter within this first edition helps open students’ minds to comprehend the big picture with sections that highlight how the different fields of psychology are connected to each other and how they connect to everyday life. This text highlights human development, brain function, abnormal psychology, and the individual differences in each area as cut-across themes to demonstrate these connections. Also included are two-page art spreads to demonstrate exactly What Happens In The Brain When we engage in everyday activities such as eat pizza, study psychology, or listen to music. The art featured in these spreads have been created especially for Psychology Around Us by an award-winning artist with input from faculty on how it will contribute to teaching and learning. Features: Cut Across Connections - Almost every chapter helps students comprehend the big picture with sections that highlight how the different fields of psychology are connected to each other and how they connect to everyday life. What Happens in the Brain When…These two-page art spreads demonstrate exactly what happens in the brain when we engage in everyday activities such as eating pizza, studying psychology, or listening to music. Chapter Opening Vignettes - Every chapter begins with a vignette that shows the power of psychology in understanding a whole range of human behaviour. This theme is reinforced throughout the chapter, celebrating the extraordinary processes that make the everyday possible. Special topics on psychology around us - Each chapter highlights interesting news stories, current controversies in psychology, and relevant research findings that demonstrate psychology around us. The Practically Speaking box emphasizes the practical application of everyday psychology. Helpful study tools - Key Terms; Marginal Definitions; Marginal Notes; Chapter Summaries.

Author:
Publisher: Academic Press
ISBN: 0128201908
Category : Medical
Languages : en
Pages : 404

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The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Author: Alexei Verkhratsky
Publisher: John Wiley & Sons
ISBN: 1118402057
Category : Medical
Languages : en
Pages : 473

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Book Description
Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Author: Sajal Chakraborti
Publisher: Springer
ISBN: 9811025134
Category : Medical
Languages : en
Pages : 619

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Book Description
Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well as their synthetic and endogenous inhibitors. The role of proteases was initially thought to be limited to general metabolic digestion. However, we now know that the role of protein breakdown is much more complex, and proteases have multiple functions: they are coupled to turnover and can affect protein composition, function and synthesis. In addition to eliminating abnormal proteins, breakdown has many modulatory functions, including activating and inactivating enzymes, modulating membrane function, altering receptor channel properties, affecting transcription and cell cycles and forming active peptides. The ubiquity of proteases in nature makes them an important target for drug development. This in-depth, comprehensive is a valuable resource for researchers involved in identifying new targets for drug development. With its multidisciplinary scope, it bridges the gap between fundamental and translational research in the biomedical and pharmaceutical industries, making it thought-provoking reading for scientists in the field.

Author: František Baluška
Publisher: Springer Science & Business Media
ISBN: 3540892303
Category : Science
Languages : fr
Pages : 312

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Book Description
Our image of plants is changing dramatically away from passive entities merely subject to environmental forces and organisms that are designed solely for the accumulation of photosynthate. Plants are revealing themselves to be dynamic and highly sensitive organisms that actively and competitively forage for limited resources, both above and below ground, organisms that accurately gauge their circumstances, use sophisticated cost-benefit analysis, and take clear actions to mitigate and control diverse environmental threats. Moreover, plants are also capable of complex recognition of self and non-self and are territorial in behavior. They are as sophisticated in behavior as animals but their potential has been masked because it operates on time scales many orders of magnitude less than those of animals. Plants are sessile organisms. As such, the only alternative to a rapidly changing environment is rapid adaptation. This book will focus on all these new and exciting aspects of plant biology.

Author: William R. Tiffany
Publisher: McGraw-Hill Humanities, Social Sciences & World Languages
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 456

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