Arthropod Venom Components and Their Potential Usage PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Arthropod Venom Components and Their Potential Usage PDF full book. Access full book title Arthropod Venom Components and Their Potential Usage by Katsuhiro Konno. Download full books in PDF and EPUB format.
Author: Katsuhiro Konno Publisher: MDPI ISBN: 3039285408 Category : Medical Languages : en Pages : 404
Book Description
Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC–MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.
Author: Katsuhiro Konno Publisher: MDPI ISBN: 3039285408 Category : Medical Languages : en Pages : 404
Book Description
Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC–MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.
Author: Gandhi Rádis-Baptista Publisher: ISBN: 9783039285419 Category : Medicine (General) Languages : en Pages : 404
Book Description
Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods' venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC-MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.
Author: Ramón Eduardo Rebolledo Ranz Publisher: BoD – Books on Demand ISBN: 1789841658 Category : Science Languages : en Pages : 234
Book Description
This book presents comprehensive information on arthropods, the most abundant and diverse group of invertebrate animals in existence today. Chapters cover such topics as arthropods as food for humans, arthropods as a bioindicator species, use of arthropods in the cosmetic and pharmaceutical industries, arthropods and their conservation status, diets for raising arthropods, and much more. It is a useful reference for undergraduate and graduate students, academics, researchers, and anyone interested in learning more about this important group of invertebrates and their current conservation status.
Author: Marcos Roberto de Oliveira Publisher: Elsevier ISBN: 0443237646 Category : Science Languages : en Pages : 2202
Book Description
Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. - Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules - Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules - Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells - Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells
Author: P. Gopalakrishnakone Publisher: Springer ISBN: 9789400763883 Category : Medical Languages : en Pages : 0
Book Description
In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
Author: S. Bettini Publisher: Springer Science & Business Media ISBN: 3642455018 Category : Medical Languages : en Pages : 998
Book Description
Arthropod venoms have received much attention and have played an important role in folklore and medicine since ancient times. Scorpion envenomation, "tarant ism," bee and wasp stings are among those subjects about which most has been speculated and written in the past. In the last 50 years or so, a great number of scientific papers have been devoted to arthropod venoms, but only a few volumes have been designed to collect this rapidly increasing material, and these are not recent. Of late, the chemistry and mode of action of several arthropod venoms have been thoroughly studied, and some of these substances will probably be used as pharmacological tools and also as therapeutic agents. The aim of the present volume is to collect in manual form new information as well as the old notions on arthropod venoms. Even though it was our intention to present a volume on arthropod venoms, and not on venomous arthropods, inevitably we were forced to include information on venom-producing organisms as well. We assumed, in fact, that those scientists for whom the present manual is primarily intended (biochemists, particularly com parative biochemists, and pharmacologists) should be familiar with the biologic elements concerning the venom-producing species; which should show them how important it is to operate in close collaboration with biologists specialized in venomous arthropod systematics and biology.
Author: Jorge M. Vivanco Publisher: Springer Science & Business Media ISBN: 3642190804 Category : Science Languages : en Pages : 123
Book Description
The mystique of the rainforest has captured the imaginations of generations of young people, explorers, authors, and biologists. It is a delicate ecosystem whose myriad sounds and smells, whose vibrancy of life, is balanced by constant cycles of death and decay. It is a place of fierce competition where unusual partnerships are forged and creative survival strategies are the norm. In this book, you will meet the scientific pioneers who first attempted to quantify and understand the vast diversity of these tropical forests, as well as their successors, who utilize modern tools and technologies to dissect the chemical nature of rainforest interactions. This book provides a general background on biodiversity and the study of chemical ecology before moving into specific chemical examples of insect defenses and microbial communication. It finishes with first-hand accounts of the trials and tribulations of a canopy biology pioneer and a rainforest research novice, while assessing the state of modern tropical research, its importance to humanity, and the ecological, political, and ethical issues that need to be tackled in order to move the field forward.
Author: P. Gopalakrishnakone Publisher: Springer ISBN: 9789400766471 Category : Medical Languages : en Pages : 550
Book Description
In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
Author: Katsuhiro Konno
Author: Katsuhiro Konno
Author: Gandhi Rádis-Baptista
Author: David W. Alsop
Author: Ramón Eduardo Rebolledo Ranz
Author: Marcos Roberto de Oliveira
Author: P. Gopalakrishnakone
Author: Jay Fox
Author: S. Bettini
Author: Jorge M. Vivanco
Author: P. Gopalakrishnakone