Author: Hamid Mirzaei
Publisher: Springer
ISBN: 3319414488
Category : Science
Languages : en
Pages : 525
Book Description
This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review articles that cover certain aspects of proteomics but they often lack technical details. Subject specific literature also lacks the broad overviews that are needed to design an experiment in which all steps are compatible and coherent. The objective of this book was to create a proteomics manual to provide scientists who are not experts in the field with an overview of: 1. The types of samples can be analyzed by mass spectrometry for proteomics analysis. 2. Ways to convert biological or ecological samples to analytes ready for mass spectral analysis. 3. Ways to reduce the complexity of the proteome to achieve better coverage of the constituent proteins. 4. How various mass spectrometers work and different ways they can be used for proteomics analysis 5. The various platforms that are available for proteomics data analysis 6. The various applications of proteomics technologies in biological and medical sciences This book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation. With the broad setup and chapters written by experts in the field, there is information that is valuable for students as well as for researchers who are looking for a hands on introduction into the strengths, weaknesses and opportunities of proteomics.
Modern Proteomics – Sample Preparation, Analysis and Practical Applications
Author: Hamid Mirzaei
Publisher: Springer
ISBN: 3319414488
Category : Science
Languages : en
Pages : 525
Book Description
This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review articles that cover certain aspects of proteomics but they often lack technical details. Subject specific literature also lacks the broad overviews that are needed to design an experiment in which all steps are compatible and coherent. The objective of this book was to create a proteomics manual to provide scientists who are not experts in the field with an overview of: 1. The types of samples can be analyzed by mass spectrometry for proteomics analysis. 2. Ways to convert biological or ecological samples to analytes ready for mass spectral analysis. 3. Ways to reduce the complexity of the proteome to achieve better coverage of the constituent proteins. 4. How various mass spectrometers work and different ways they can be used for proteomics analysis 5. The various platforms that are available for proteomics data analysis 6. The various applications of proteomics technologies in biological and medical sciences This book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation. With the broad setup and chapters written by experts in the field, there is information that is valuable for students as well as for researchers who are looking for a hands on introduction into the strengths, weaknesses and opportunities of proteomics.
Publisher: Springer
ISBN: 3319414488
Category : Science
Languages : en
Pages : 525
Book Description
This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review articles that cover certain aspects of proteomics but they often lack technical details. Subject specific literature also lacks the broad overviews that are needed to design an experiment in which all steps are compatible and coherent. The objective of this book was to create a proteomics manual to provide scientists who are not experts in the field with an overview of: 1. The types of samples can be analyzed by mass spectrometry for proteomics analysis. 2. Ways to convert biological or ecological samples to analytes ready for mass spectral analysis. 3. Ways to reduce the complexity of the proteome to achieve better coverage of the constituent proteins. 4. How various mass spectrometers work and different ways they can be used for proteomics analysis 5. The various platforms that are available for proteomics data analysis 6. The various applications of proteomics technologies in biological and medical sciences This book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation. With the broad setup and chapters written by experts in the field, there is information that is valuable for students as well as for researchers who are looking for a hands on introduction into the strengths, weaknesses and opportunities of proteomics.
Molecular Biology of the Cell
Biosafety in the Laboratory
Author: Division on Engineering and Physical Sciences
Publisher: National Academies Press
ISBN: 0309039754
Category : Science
Languages : en
Pages : 237
Book Description
Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.
Publisher: National Academies Press
ISBN: 0309039754
Category : Science
Languages : en
Pages : 237
Book Description
Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.
Essential Clinical Procedures
Author: Richard W. Dehn, MPA, PA-C
Publisher: Elsevier Health Sciences
ISBN: 1455707813
Category : Medical
Languages : en
Pages : 467
Book Description
Written by foremost experts in the field, the 3rd Edition of Essential Clinical Procedures presents the latest common diagnostic and treatment-related procedures that you need to know as a physician assistant! Clear and concise, this medical reference book leads you step-by-step through over 70 techniques commonly seen in primary care and specialist settings, equipping you to deliver the best and safest care to your patients. Visualize procedures and other important concepts clearly through over 300 high-quality illustrations. Ensure the safe execution of procedures with a focus on patient preparation and the proper use of instruments, as well as highlighted warnings to alert you to potential dangers that can occur when performing various treatments. Be fully prepared for any situation with guidance on the possible complications, rationales, and precautions behind many common procedures. Understand the ins and outs of nonprocedural issues, including informed consent, standard precautions, patient education, and procedure documentation. Get all the hands-on guidance you need to provide safe and effective care to your patients with Essential Clinical Procedures! Understand the "must-know" aspects of the most commonly seen conditions with a systematic presentation featuring consistent headings and supporting color images. Quickly access core information through high-yield margin notes and consistent formatting across all chapters. Stay abreast of the latest procedures with a brand-new chapter and images on Reduction of the Shoulder/Finger Subluxations, plus many other updates throughout. Access the fully searchable text online at www.expertconsult.com!
Publisher: Elsevier Health Sciences
ISBN: 1455707813
Category : Medical
Languages : en
Pages : 467
Book Description
Written by foremost experts in the field, the 3rd Edition of Essential Clinical Procedures presents the latest common diagnostic and treatment-related procedures that you need to know as a physician assistant! Clear and concise, this medical reference book leads you step-by-step through over 70 techniques commonly seen in primary care and specialist settings, equipping you to deliver the best and safest care to your patients. Visualize procedures and other important concepts clearly through over 300 high-quality illustrations. Ensure the safe execution of procedures with a focus on patient preparation and the proper use of instruments, as well as highlighted warnings to alert you to potential dangers that can occur when performing various treatments. Be fully prepared for any situation with guidance on the possible complications, rationales, and precautions behind many common procedures. Understand the ins and outs of nonprocedural issues, including informed consent, standard precautions, patient education, and procedure documentation. Get all the hands-on guidance you need to provide safe and effective care to your patients with Essential Clinical Procedures! Understand the "must-know" aspects of the most commonly seen conditions with a systematic presentation featuring consistent headings and supporting color images. Quickly access core information through high-yield margin notes and consistent formatting across all chapters. Stay abreast of the latest procedures with a brand-new chapter and images on Reduction of the Shoulder/Finger Subluxations, plus many other updates throughout. Access the fully searchable text online at www.expertconsult.com!
Single Cell Analysis
Author: Dario Anselmetti
Publisher: John Wiley & Sons
ISBN: 3527626654
Category : Science
Languages : en
Pages : 284
Book Description
The first-ever comprehensive overview of the methods used in this key technology in modern biology provides the latest working knowledge needed by every scientist entering this growing field. It covers all the current technology and application areas, from microscopy and spectroscopy to proteomics and microfluidics.
Publisher: John Wiley & Sons
ISBN: 3527626654
Category : Science
Languages : en
Pages : 284
Book Description
The first-ever comprehensive overview of the methods used in this key technology in modern biology provides the latest working knowledge needed by every scientist entering this growing field. It covers all the current technology and application areas, from microscopy and spectroscopy to proteomics and microfluidics.
Specification of Drug Substances and Products
Author: Christopher M. Riley
Publisher: Elsevier
ISBN: 0443134677
Category : Science
Languages : en
Pages : 910
Book Description
Specification of Drug Substances and Drug Products is a fully comprehensive reference on Specification Setting for Pharmaceuticals. There have been several recent developments in the ICH Guidelines, which were not captured in previous editions, notably the new guideline on Development of Analytical Procedure and the revisions to the validation guidelines, and the specification guidelines. This edition contains chapters discussing the unique requirements for the universal critical quality attributes, as well as the specific tests required to characterize and control different types of products, ranging in complexity from small molecules in immediate release oral dosage forms to complex products such as drug-antibody conjugates and mRNA-based products. This substantially expanded revision of the 2nd edition will serve as practical comprehensive reference for scientists, managers, educators, and consultants involved in the development and regulation of pharmaceutical products - Presents critical assessment, potential impact, and application of the recent revisions to ICH guidelines on method validation (Q2) (as well as the latest guideline on Analytical Method Development (Q14), and the special regional requirements in non-ICH regions. - Addresses comprehensive treatment of the development and validation of analytical methodologies used in the analysis, control, and specification of a variety of different types of dosage forms, ranging from traditional oral solid dosage forms to proteins, nRNA-based drugs, vaccines, and gene therapy. This book will also address drug–device combination products such as digital drug delivery systems, transdermal systems, and inhalation products. - Presents detailed treatment of latest statistical approaches, including new approaches to the treatment of validation data method, specification setting, and shelf-life prediction (based on stability data).
Publisher: Elsevier
ISBN: 0443134677
Category : Science
Languages : en
Pages : 910
Book Description
Specification of Drug Substances and Drug Products is a fully comprehensive reference on Specification Setting for Pharmaceuticals. There have been several recent developments in the ICH Guidelines, which were not captured in previous editions, notably the new guideline on Development of Analytical Procedure and the revisions to the validation guidelines, and the specification guidelines. This edition contains chapters discussing the unique requirements for the universal critical quality attributes, as well as the specific tests required to characterize and control different types of products, ranging in complexity from small molecules in immediate release oral dosage forms to complex products such as drug-antibody conjugates and mRNA-based products. This substantially expanded revision of the 2nd edition will serve as practical comprehensive reference for scientists, managers, educators, and consultants involved in the development and regulation of pharmaceutical products - Presents critical assessment, potential impact, and application of the recent revisions to ICH guidelines on method validation (Q2) (as well as the latest guideline on Analytical Method Development (Q14), and the special regional requirements in non-ICH regions. - Addresses comprehensive treatment of the development and validation of analytical methodologies used in the analysis, control, and specification of a variety of different types of dosage forms, ranging from traditional oral solid dosage forms to proteins, nRNA-based drugs, vaccines, and gene therapy. This book will also address drug–device combination products such as digital drug delivery systems, transdermal systems, and inhalation products. - Presents detailed treatment of latest statistical approaches, including new approaches to the treatment of validation data method, specification setting, and shelf-life prediction (based on stability data).
Fundamentals of Environmental Sampling and Analysis
Author: Chunlong Zhang
Publisher: John Wiley & Sons
ISBN: 111977859X
Category : Science
Languages : en
Pages : 581
Book Description
Fundamentals of Environmental Sampling and Analysis A fully reworked and updated introduction to the fundamentals and applications of environmental sampling and analysis Environmental sampling and analysis are essential components of environmental data acquisition and scientific research. The acquisition of reliable data with respect to proper sampling, chemical and instrumental methodology, and QA/QC is a critical precursor to all environmental work. No would-be environmental scientist, engineer, or policymaker can succeed without an understanding of how to correctly acquire, assess and use credible data. Fundamentals of Environmental Sampling and Analysis, 2nd edition provides this understanding, with a comprehensive survey of the theory and applications of these critical sampling and analytical tools. The field of environmental research has expanded greatly since the publication of the first edition, and this book has been completely rewritten to reflect the latest studies and technological developments. The resulting mix of theory and practice will continue to serve as the standard introduction to the subject. Readers of the second edition of Fundamentals of Environmental Sampling and Analysis will also find: Three new chapters and numerous expanded sections on topics of emerging environmental concerns Detailed discussion of subjects including passive sampling, Raman spectroscopy, non-targeted mass spectroscopic analysis, and many more Over 500 sample problems and solutions along with other supplementary instructional materials Fundamentals of Environmental Sampling and Analysis is ideal for students of environmental science and engineering as well as professionals and regulators for whom reliable environmental data through sampling and analysis is critical.
Publisher: John Wiley & Sons
ISBN: 111977859X
Category : Science
Languages : en
Pages : 581
Book Description
Fundamentals of Environmental Sampling and Analysis A fully reworked and updated introduction to the fundamentals and applications of environmental sampling and analysis Environmental sampling and analysis are essential components of environmental data acquisition and scientific research. The acquisition of reliable data with respect to proper sampling, chemical and instrumental methodology, and QA/QC is a critical precursor to all environmental work. No would-be environmental scientist, engineer, or policymaker can succeed without an understanding of how to correctly acquire, assess and use credible data. Fundamentals of Environmental Sampling and Analysis, 2nd edition provides this understanding, with a comprehensive survey of the theory and applications of these critical sampling and analytical tools. The field of environmental research has expanded greatly since the publication of the first edition, and this book has been completely rewritten to reflect the latest studies and technological developments. The resulting mix of theory and practice will continue to serve as the standard introduction to the subject. Readers of the second edition of Fundamentals of Environmental Sampling and Analysis will also find: Three new chapters and numerous expanded sections on topics of emerging environmental concerns Detailed discussion of subjects including passive sampling, Raman spectroscopy, non-targeted mass spectroscopic analysis, and many more Over 500 sample problems and solutions along with other supplementary instructional materials Fundamentals of Environmental Sampling and Analysis is ideal for students of environmental science and engineering as well as professionals and regulators for whom reliable environmental data through sampling and analysis is critical.
Strengthening Forensic Science in the United States
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309142393
Category : Law
Languages : en
Pages : 348
Book Description
Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.
Publisher: National Academies Press
ISBN: 0309142393
Category : Law
Languages : en
Pages : 348
Book Description
Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.
Essential Clinical Procedures E-Book
Author: Richard W. Dehn
Publisher: Elsevier Health Sciences
ISBN: 0323624685
Category : Medical
Languages : en
Pages : 465
Book Description
Provide safe and effective care to every patient with the fully revised 4th Edition of Essential Clinical Procedures. Written by experts in the field, this widely used reference shows you step by step how to perform more than 70 of the most common diagnostic and treatment-related procedures in today's primary care and specialist settings. You'll find clear, concise coverage of the skills you need to know, including new and advanced procedures and new procedure videos. - Covers patient preparation, the proper use of instruments, and potential dangers and complications involved in common procedures, as well as nonprocedural issues such as informed consent, standard precautions, patient education, and procedure documentation. - Includes new chapters on Point-of-Care Ultrasound and Ring Removal, as well as 34 new procedure videos. - Features significantly revised content on cryosurgery • injection techniques • arterial puncture • shoulder/finger subluxations • sterile technique • outpatient coding • casting and splinting • blood cultures • standard precautions • and more. - Contains more than 200 high-quality illustrations, including updated images of office pulmonary function testing and wound closure. - Uses a consistently formatted presentation to help you find information quickly. - Reflects the latest evidence-based protocols and national and international guidelines throughout. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Publisher: Elsevier Health Sciences
ISBN: 0323624685
Category : Medical
Languages : en
Pages : 465
Book Description
Provide safe and effective care to every patient with the fully revised 4th Edition of Essential Clinical Procedures. Written by experts in the field, this widely used reference shows you step by step how to perform more than 70 of the most common diagnostic and treatment-related procedures in today's primary care and specialist settings. You'll find clear, concise coverage of the skills you need to know, including new and advanced procedures and new procedure videos. - Covers patient preparation, the proper use of instruments, and potential dangers and complications involved in common procedures, as well as nonprocedural issues such as informed consent, standard precautions, patient education, and procedure documentation. - Includes new chapters on Point-of-Care Ultrasound and Ring Removal, as well as 34 new procedure videos. - Features significantly revised content on cryosurgery • injection techniques • arterial puncture • shoulder/finger subluxations • sterile technique • outpatient coding • casting and splinting • blood cultures • standard precautions • and more. - Contains more than 200 high-quality illustrations, including updated images of office pulmonary function testing and wound closure. - Uses a consistently formatted presentation to help you find information quickly. - Reflects the latest evidence-based protocols and national and international guidelines throughout. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
The Molecular Basis of Human Cancer
Author: William B. Coleman
Publisher: Humana Press
ISBN: 1597454583
Category : Medical
Languages : en
Pages : 868
Book Description
This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.
Publisher: Humana Press
ISBN: 1597454583
Category : Medical
Languages : en
Pages : 868
Book Description
This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.