Author: Teresa Catherine CainPublisher:
ISBN:
Category :
Languages : en
Pages : 234
Book Description
Application of Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry to the Study of Bacterial Biomolecules
Author: Teresa Catherine CainPublisher:
ISBN:
Category :
Languages : en
Pages : 234
Book Description
Application of Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry to the Study of Bacteriocins
Author: Natisha Linda RosePublisher:
ISBN:
Category : Bacteriocins
Languages : en
Pages : 282
Book Description
Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry
Author: Rainer CramerPublisher: Springer
ISBN: 3319048198
Category : Science
Languages : en
Pages : 287
Book Description
This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics
Applications of MALDI-TOF Spectroscopy
Author: Zongwei CaiPublisher: Springer
ISBN: 3642356656
Category : Science
Languages : en
Pages : 220
Book Description
MALDI-ToF Mass Spectrometry for Studying Noncovalent Complexes of Biomolecules, by Stefanie Mädler, Elisabetta Boeri Erba, Renato Zenobi Application of MALDI-TOF-Mass Spectrometry to Proteome Analysis Using Stain-Free Gel Electrophoresis, by Iuliana Susnea, Bogdan Bernevic, Michael Wicke, Li Ma, Shuying Liu, Karl Schellander, Michael Przybylski MALDI Mass Spectrometry for Nucleic Acid Analysis, by Xiang Gao, Boon-Huan Tan, Richard J. Sugrue, Kai Tang Determination of Peptide and Protein Disulfide Linkages by MALDI Mass Spectrometry, by Hongmei Yang, Ning Liu, Shuying Liu MALDI In-Source Decay, from Sequencing to Imaging, by Delphine Debois, Nicolas Smargiasso, Kevin Demeure, Daiki Asakawa, Tyler A. Zimmerman, Loïc Quinton, Edwin De Pauw Advances of MALDI-TOF MS in the Analysis of Traditional Chinese Medicines, by Minghua Lu, Zongwei Cai Chemical and Biochemical Applications of MALDI TOF-MS Based on Analyzing the Small Organic Compounds, by Haoyang Wang, Zhixiong Zhao, Yinlong Guo Bioinformatic Analysis of Data Generated from MALDI Mass Spectrometry for Biomarker Discovery, by Zengyou He, Robert Z. Qi, Weichuan Yu
Two-Laser Matrix Assisted Laser Desorption/Laser Ionization Time-of-Flight Mass Spectrometry of Biomolecules
Author: Publisher:
ISBN:
Category :
Languages : en
Pages : 22
Book Description
Recent efforts to detect and identify large biomolecules using matrix assisted laser desorption have shown MALDI to be an extremely sensitive technique for trace detection from a solid sample. In the DI process, ions are formed by proton transfer from an electronically excited organic acid to a suitable proton accepting analyte. However, detection and characterization of biomolecules may benefit from ionization of the isolated unprotonated gas phase neutrals. To this end, a custom time-of-flight mass spectrometer as been constructed to perform two-laser matrix assisted laser desorption/laser ionization studies using separate desorption and ionization lasers. The two chamber, differentially pumped apparatus incorporates numerous laser and sample probe entry ports, a pulsed valve, and a modified Wiley-NcLaren mass spectrometer design. Results of initial two-laser experiments on phenylalanine in a sinnapinic acid matrix have demonstrated the apparatus' ability to detect laser ionization of laser desorbed neutrals.
Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry
Author: Haroun N. ShahPublisher: John Wiley & Sons
ISBN: 1119814073
Category : Science
Languages : en
Pages : 565
Book Description
Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry Detailed resource presenting the capabilities of MALDI mass spectrometry (MS) to industrially and environmentally significant areas in the biosciences Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry fulfills a need to bring the key analytical technique of MALDI mass spectrometric analysis into routine practice by specialists and non-specialists, and technicians. It informs and educates established researchers on the development of techniques as applied to industrially significant areas within the biosciences. Throughout the text, the reader is presented with recognized and emerging techniques of this powerful and continually advancing field of analytical science to key areas of importance. While many scientific papers are reporting new applications of MS-based analysis in specific foci, this book is unique in that it draws together an incredibly diverse range of applications that are pushing the boundaries of MS across the broad field of biosciences. Contributed to by recognized experts in the field of MALDI MS who have been key players in promoting the advancement and dissemination of authoritative information in this field, Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry covers sample topics such as: Oil microbiology, marine and freshwater ecosystems, agricultural and food microbiology, and industrial waste microbiology Bioremediation and landfill sites microbiology, microbiology of inhospitable sites (e.g. Arctic and Antarctic, and alkaline and acidic sites, and hot temperatures) Veterinary, poultry and animals, viral applications of MS, and antibiotic resistance using tandem MS methods Recent developments which are set to transform the use of MS from its success in clinical microbiology to a wide range of commercial and environmental uses Bridging the gap between measurement and key applications, this text is an ideal resource for industrial and environmental analytical scientists, including technologists in the food industry, pharmaceuticals, and agriculture, as well as biomedical scientists, researchers, clinicians and academics and scientists in bio-resource centers.
Matrix-assisted Laser Desorption/ionization Mass Spectrometric Study of Biologic Molecules
Author: Yan-Hui LiuTime-of-flight Mass Spectrometry
Author: Robert J. CotterPublisher:
ISBN:
Category : Science
Languages : en
Pages : 360
Book Description
This book presents the basic principles of time-of-flight (TOF) mass spectrometry with a strong emphasis on applications in biological research. It describes many innovative techniques, including orthogonal extraction, post source decay, and delayed extraction, and surveys ionization techniques used on TOF mass spectrometers such as electron impact, plasma desorption, SIMS, FAB, laser desorption, MALDI, and electrospray. The book features chapters on applications to peptides/proteins, oligonucleotides, and other biological macromolecules, and examines how techniques might be used in sequencing the human genome.
Principles and Applications of Clinical Mass Spectrometry
Author: Nader RifaiPublisher: Elsevier
ISBN: 0128160640
Category : Science
Languages : en
Pages : 218
Book Description
Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field
Author: Yongdong Zhu