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Author: Michael G. Fehlings Publisher: Thieme ISBN: 1638531579 Category : Medical Languages : en Pages : 291
Book Description
World-renowned experts share the latest updates in translational research as well as surgical and nonsurgical strategies for treating spinal cord injury Spinal cord injury (SCI) is a devastating, clinically challenging injury, leading to varying degrees of neurological function impairment and paralysis. Underlying biological mechanisms either inhibit or promote new growth in the spinal cord. Researchers have been making important discoveries about how neurons and their axons grow in the central nervous system and why they fail to regenerate after SCI. Although progress has been steady, there remains an urgent need to address issues in acute management such as early decompression and the use of biologics, as well as potential solutions for regeneration. Written by renowned experts in the ever-evolving field of SCI research and clinical practice, the 7th volume in the AOSpine Masters series is a state-of-the-art compendium on the latest in SCI diagnosis, spine surgery interventions, and long-term management. Each chapter contains pearls from leading spine specialists gleaned from the research laboratory and years of hands-on experience treating SCI patients in the emergency setting and long term. Key Features: Pathobiology, assessment, and diagnostic considerations The use of biomarkers as predictors of functional recovery Surgical and nonsurgical interventions for traumatic SCI The role of neural stem cells and biologics in spinal cord repair Functional and epidural stimulation and brain-computer interfaces The AOSpine Masters series, a copublication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evolving, dynamic model of evidence-based approach to spine care. This essential textbook delivers invaluable insights to spine surgeons, spinal cord injury clinicians and researchers and trainees, from translational researchers to experienced researchers and clinicians experienced in the operative and non-operative management of spinal cord injury.
Author: Michael G. Fehlings Publisher: Thieme ISBN: 1638531579 Category : Medical Languages : en Pages : 291
Book Description
World-renowned experts share the latest updates in translational research as well as surgical and nonsurgical strategies for treating spinal cord injury Spinal cord injury (SCI) is a devastating, clinically challenging injury, leading to varying degrees of neurological function impairment and paralysis. Underlying biological mechanisms either inhibit or promote new growth in the spinal cord. Researchers have been making important discoveries about how neurons and their axons grow in the central nervous system and why they fail to regenerate after SCI. Although progress has been steady, there remains an urgent need to address issues in acute management such as early decompression and the use of biologics, as well as potential solutions for regeneration. Written by renowned experts in the ever-evolving field of SCI research and clinical practice, the 7th volume in the AOSpine Masters series is a state-of-the-art compendium on the latest in SCI diagnosis, spine surgery interventions, and long-term management. Each chapter contains pearls from leading spine specialists gleaned from the research laboratory and years of hands-on experience treating SCI patients in the emergency setting and long term. Key Features: Pathobiology, assessment, and diagnostic considerations The use of biomarkers as predictors of functional recovery Surgical and nonsurgical interventions for traumatic SCI The role of neural stem cells and biologics in spinal cord repair Functional and epidural stimulation and brain-computer interfaces The AOSpine Masters series, a copublication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evolving, dynamic model of evidence-based approach to spine care. This essential textbook delivers invaluable insights to spine surgeons, spinal cord injury clinicians and researchers and trainees, from translational researchers to experienced researchers and clinicians experienced in the operative and non-operative management of spinal cord injury.
Author: Michael Fehlings Publisher: Academic Press ISBN: 0128198362 Category : Medical Languages : en Pages : 646
Book Description
Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples
Author: Jeffrey Wang Publisher: Thieme ISBN: 1638531587 Category : Medical Languages : en Pages : 322
Book Description
Current statistics indicate that 75-80% of people worldwide will experience some form of back pain during their lifetime. Lumbar pain is a leading cause of disability - a global public health burden with serious economic implications. Written by internationally renowned spine experts, the 8th volume in the AOSpine Masters series is a concise, state-of-the-art overview on fundamental management strategies and current issues and challenges. The text covers the full age spectrum - from childhood to older adulthood - and contributing factors such as the sacroiliac joints, genetics, and spine infections. Clinical evaluation, treatment options, recent research advances, and future perspectives are systematically examined and presented in a clear format. With commentary from leading authorities, this compendium presents candid discussion of significant challenges faced by clinicians who treat back pain. Among the issues addressed are managing patients who have undergone multiple operations, chronic back pain, failed spine surgery, and what to do when all nonsurgical and surgical options have been exhausted. Key Highlights Economic considerations, risk factors, and legal aspects Neurological causes, including myopathies, neuromuscular disease, Parkinson disease,and dystonia Conservative treatment options such as drugs, physiotherapy, and complementary medicine The role of minimally invasive surgery in treating degenerative lumbar spine disease Must-read bibliographic references in every chapter Bullet lists of pearls and pitfalls summarize critical points and key concepts The AOSpine Masters series, a co-publication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evolving, dynamic model of evidence-based approach to spine care.
Author: S. Rajasekaran Publisher: Thieme ISBN: 1626234566 Category : Medical Languages : en Pages : 302
Book Description
Renowned spine experts share recent advances on the management of spinal infections AOSpine Masters Series, Volume 10: Spinal Infections is a concise, state-of-the-art review covering all aspects of spinal infections – from basic science and epidemiology to fundamental surgical and nonsurgical approaches. Internationally renowned spine surgeons Luis Roberto Vialle, S. Rajasekaran, Rishi Kanna, Giuseppe Barbagallo, and many experts across the world, provide clinical pearls and insights gleaned from years of hands-on expertise. This book provides discussion of underlying pathologies, imaging and diagnosis, and surgical techniques, with a focus on issues specific to children, co-infection with HIV, postoperative problems, geriatric patients, and pseudoarthrosis. Key Highlights Overviews on the epidemiology, microbiology, and pathology of spinal infections Detailed review of imaging, and other investigations Treatment planning and surgical techniques Risk stratification and prevention of post-operative infection Pathogenesis, clinical features, diagnosis, and treatment of pyogenic spondylodiscitis in various regions of the spine Clinical pearls on the management of spinal tuberculosis, including drug therapy and surgery The AOSpine Masters series, a co-publication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evidence-based approach to spine care. This textbook is essential reading for all spine surgeons. Orthopaedic and neurosurgery residents, as well as veteran surgeons will find this a useful tool for daily practice.
Author: Marinus de Kleuver Publisher: Thieme ISBN: 162623454X Category : Medical Languages : en Pages : 318
Book Description
An estimated 9 million children every year are affected by pediatric spinal deformities, encompassing a broad spectrum of pathologies. New classification systems, innovative imaging modalities, and advances in surgical techniques have contributed to a continually evolving, evidence-based treatment paradigm. Patient variables such as the age of onset, severity, course of deformity progression, as well as the availability of technology pose individualized challenges. AOSpine Masters Series, Volume 9: Pediatric Spinal Deformity is a concise yet comprehensive review of fundamental surgical and nonsurgical approaches, contemporary issues, and treatment obstacles. Internationally renowned spine surgeons Luis Roberto Vialle, Marinus de Kleuver, and Sigurd Berven and a cadre of esteemed contributors deliver a state-of-the-art reference on deformities of the pediatric spine. From early childhood to adolescent spine disorders, 17 richly illustrated chapters cover diagnosis, preoperative evaluation, imaging, spine surgery interventions, non-fusion procedures, and long-term management. Key Highlights Overviews on the classification and natural history of early onset scoliosis and adolescent idiopathic scoliosis, with subsequent chapters covering non-operative management and contemporary surgical techniques Evidence-based discussion of long-term surgical care outcomes, indications for revision surgery, and strategies for achieving optimal results Management of congenital and developmental kyphosis, lordosis, syndromic conditions, and low and high grade spondylolisthesis Clinical pearls on spine surgery in the developing world, safety issues and complications, and the importance of developing outcome metrics The AOSpine Masters series, a copublication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evolving, dynamic model of evidence-based approach to spine care. This outstanding textbook is a must have for spine surgeons, in particular those who specialize in treating childhood spine disorders. Orthopaedic and neurosurgery residents, as well as veteran surgeons with extensive knowledge will find this an indispensable tool for daily practice.
Author: Steven R. Garfin Publisher: Elsevier Health Sciences ISBN: 0323511953 Category : Medical Languages : en Pages : 2127
Book Description
Get comprehensive, practical coverage of both surgical and non-surgical treatment approaches from the world's most trusted authorities in spine surgery and care. Rothman-Simeone and Herkowitz's The Spine, 7th Edition, edited by Drs. Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, and Christopher M. Bono, presents state-of-the-art techniques helping you apply today's newest developments in your practice. - Highlights critical information through the use of pearls, pitfalls, and key points throughout the text, as well as more than 2,300 full-color photographs and illustrations. - Offers a newly revised, streamlined format that makes it easier than ever to find the information you need. - Contains new chapters on the clinical relevance of finite element modeling and SI joint surgery. - Includes an expanded section on minimally invasive spine surgery, including recent developments and future directions. - Provides the latest evidence-based research from high-quality studies, including new randomized controlled trials for lumbar stenosis, surgery, fusion, and injections. - Presents the knowledge and expertise of new international contributors, as well as new editorial leadership from Dr. Steven Garfin. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Author: Luiz Roberto Gomes Vialle Publisher: Thieme ISBN: 1626232288 Category : Medical Languages : en Pages : 291
Book Description
World-renowned experts share the latest updates in translational research as well as surgical and nonsurgical strategies for treating spinal cord injury Spinal cord injury (SCI) is a devastating, clinically challenging injury, leading to varying degrees of neurological function impairment and paralysis. Underlying biological mechanisms either inhibit or promote new growth in the spinal cord. Researchers have been making important discoveries about how neurons and their axons grow in the central nervous system and why they fail to regenerate after SCI. Although progress has been steady, there remains an urgent need to address issues in acute management such as early decompression and the use of biologics, as well as potential solutions for regeneration. Written by renowned experts in the ever-evolving field of SCI research and clinical practice, the 7th volume in the AOSpine Masters series is a state-of-the-art compendium on the latest in SCI diagnosis, spine surgery interventions, and long-term management. Each chapter contains pearls from leading spine specialists gleaned from the research laboratory and years of hands-on experience treating SCI patients in the emergency setting and long term. Key Features: Pathobiology, assessment, and diagnostic considerations The use of biomarkers as predictors of functional recovery Surgical and nonsurgical interventions for traumatic SCI The role of neural stem cells and biologics in spinal cord repair Functional and epidural stimulation and brain-computer interfaces The AOSpine Masters series, a copublication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evolving, dynamic model of evidence-based approach to spine care. This essential textbook delivers invaluable insights to spine surgeons, spinal cord injury clinicians and researchers and trainees, from translational researchers to experienced researchers and clinicians experienced in the operative and non-operative management of spinal cord injury.
Author: Benjamin Gantenbein Publisher: Mdpi AG ISBN: 9783036527543 Category : Languages : en Pages : 138
Book Description
This book provides a brief snapshot of recent research on the subject of intervertebral disc degeneration and how this specific organ could be regenerated. It provides stimuli to the reader in representing research from different angles in this cross-disciplinary field of spine surgeons, mechanical engineers and biologists. In particular, it is instructive as to how disc herniations could be successfully induced in vitro and, also, to how novel cell-based therapies using rare autochthonous stem cells could potentially be used in the future.
Author: Jack Jallo Publisher: Thieme ISBN: 1626233403 Category : Medical Languages : en Pages : 1124
Book Description
"This book really is a complete primer on the head injured patient. Without a map such as the one this book metaphorically provides, the voyage to mastery can be hazardous for both practitioner and patient."— Journal of the American Medical Association Neurotrauma and Critical Care of the Brain, 2nd edition by renowned neurosurgeons Jack Jallo and Christopher Loftus incorporates salient components of the highly praised first edition. The updated text reflects cutting-edge discussion on traumatic brain injury management in a neurocritical care setting. Contributions from top experts in neurosurgery, neurology, critical care, cardiac and pulmonary care, and trauma surgery provide a concise review of a complex and evolving field. The book lays a solid foundation with discussion of TBI classification, pathophysiology, key blood biomarkers, noninvasive neuromonitoring in severe TBI patients, multimodality monitoring in neurocritical care, and brain imaging modalities. From the prehospital setting to intensive care, top experts share clinical pearls and core guidelines on the management of mild, moderate, and severe TBI and complications. Chapters new to this edition include concomitant injuries, orbital/facial fractures, vascular injuries, spine fractures, autonomic dysfunction, and temperature management. Key Highlights Specialized topics include wartime penetrating injuries, cardiovascular complications of TBI, venous thromboembolism prophylaxis, ethical considerations, TBI costs in the U.S. and the financial return on helmets Management of pediatric brain injuries in the NICU with illustrative cases Nearly 200 high quality illustrations facilitate understanding of complex anatomy and techniques Summary tables provide a handy overview of injury type, causes, characteristics, and recommended imaging modalities This remarkable resource is essential reading for neurosurgeons, neurologists, trauma physicians, critical care and rehabilitation medicine specialists, and residents in these specialties. Paired with Neurotrauma and Critical Care of the Spine, 2nd edition, this dynamic duo is the most up-to-date neurocritical care reference available today.
Author: J. Andrew Taylor Publisher: Springer ISBN: 1493966642 Category : Medical Languages : en Pages : 286
Book Description
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury (SCI). Those with an SCI are two to five times more likely to die prematurely than people without a spinal cord injury, with worse survival rates in low- and middle-income countries. Dynamic aerobic requires integrated physiologic responses across the musculoskeletal, cardiovascular, autonomic, pulmonary, thermoregulatory, and immunologic systems. Moreover, regular aerobic exercise beneficially impacts these same systems, reducing the risk for a range of diseases and maladies. This book will present comprehensive information on the unique physiologic effects of SCI and the potential role of exercise in treating and mitigating these effects. In addition, it will incorporate work from scientists across a number of disciplines and have contributors at multiple levels of investigation and across physiologic systems. Furthermore, SCI can be considered an accelerated form of aging due to the severely restricted physical inactivity imposed, usually at an early age. Therefore, the information presented may have a broader importance to the physiology of aging as it relates to inactivity. Lastly, the need for certain levels of regular aerobic exercise to engender adaptations beneficial to health is not altered by the burden of an SCI. Indeed, the amounts of exercise necessary may be even greater than the able-bodied due to ‘passive’ ambulation. This book will also address the potential health benefits for those with an SCI that can be realized if a sufficient exercise stimulus is provided.
Author: Michael G. Fehlings
Author: Michael G. Fehlings
Author: Michael Fehlings
Author: Jeffrey Wang
Author: S. Rajasekaran
Author: Marinus de Kleuver
Author: Steven R. Garfin
Author: Luiz Roberto Gomes Vialle
Author: Benjamin Gantenbein
Author: Jack Jallo
Author: J. Andrew Taylor