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Author: Oluwafemi Oguntibeju Publisher: BoD – Books on Demand ISBN: 9535112155 Category : Medical Languages : en Pages : 384
Book Description
The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.
Author: Oluwafemi Oguntibeju Publisher: BoD – Books on Demand ISBN: 9535112155 Category : Medical Languages : en Pages : 384
Book Description
The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.
Author: Mallappa Kumara Swamy Publisher: Springer Nature ISBN: 9811517614 Category : Science Languages : en Pages : 619
Book Description
Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.
Author: Halina Maria Ekiert Publisher: Springer ISBN: 9783030781590 Category : Science Languages : en Pages : 861
Book Description
This book provides a comprehensive reference guide to plant-derived antioxidants, their beneficial effects, mechanisms of action, and role in disease prevention and improving general health (anti-ageing effect). The content is divided into three main parts, the first of which covers various antioxidants (such as polyphenols, carotenoids, tocopherols, tocotrienols, glutathione, ascorbic acid), their origins, plant biochemistry and industrial utilization. In turn, the book’s second, main part focuses on antioxidants’ beneficial health effects, explains biochemical fundamentals such as the free radical theory and oxidative stress, and discusses antioxidants’ role in e.g. cancer, cardiovascular diseases, inflammation, degenerative diseases and ageing. The third part reviews general laboratory methods for antioxidant screening, preservation and determination. Written by an international team of experts, this highly interdisciplinary book will benefit a broad range of health professionals and researchers working in biochemistry, biotechnology, nutrition, plant science and food chemistry. It offers an indispensable, up-to-date guide for anyone interested in antioxidants and the role of a plant-based diet in disease prevention and control
Author: José Manuel Lorenzo Publisher: ISBN: 9781536178166 Category : Anthocyanins Languages : en Pages : 395
Book Description
Anthocyanins are compounds associated with multiple interesting effects and potential applications. This group of natural compounds can be found in many foods (ranging from red to blue depending on the matrix) such as berries, eggplant, plums, black beans and red grapes. Moreover, the knowledge accumulated so far support the key role of anthocyanins in food and pharmaceutical industry, research and in the life of consumers. The versatility of effects attributed to anthocyanins is disclosed in this book by covering several aspects ranging from its chemical and physical characteristics, separation and identification, techniques to preserve isolated compounds and reaching the healthy benefits and its use in sports.In Chapter 1, the fundaments and main aspects related to anthocyanins are disclosed. The scientific evidence indicates positive effects were related to anticancer, antioxidant, antidiabetic and inflammatory effects, for instance. In addition, anthocyanins are excellent food additives by improving the color of food in the range between red and blue. Moreover, the applications are also related to strategies to extract and improve the stability of isolated compounds. A successful isolation is necessary to obtain anthocyanins for pharmaceutical and food applications. Chapter 2 aimed to explore the concepts and advances made to improve the recovery of anthocyanins from several types of sources. It also explored the characteristics of both conventional and novel technologies.The isolation of anthocyanins also requires an adequate approach to identify and quantify each compound within this class. Chapter 3 is dedicated to discuss the approaches to identify and quantify anthocyanins, particularly for mass spectroscopic, nuclear magnetic resonance and high performance liquid chromatography. In addition, the aspects related to method validation are also explored. Once the extraction and adequate quantification of isolated anthocyanins occurs, it is of great value to prevent their degradation. The concepts and use of encapsulation technique are discussed in Chapter 4. Particular attention is given to the methods and the composition of encapsulating material to improve stability.Prior to considering the biological effect and health benefits associated with the consumption of anthocyanins, the consumption and crucial events during the digestion and absorption must be considered in order to clarify and support strategies in food and pharmaceutical applications. The concepts, biological events (with emphasis on digestion) and the role of gut microbiota on the bioaccessibility and bioavailability of anthocyanins are presented in Chapter 5. Following the absorption of anthocyanins several biological effects related to health benefits were reported in scientific literature. The first and preserve knowledge is related to the traditional consumption in order to treat diseases in folk medicine. This perspective and the scientific evidence raised so far are compiled in Chapter 6. In the chapter, the different plants sources to treat diseases are described.In Chapter 7, the relation between anthocyanins and antioxidant activity is discussed. The chapter contains the fundaments and scientific data regarding oxidative stress, lipid oxidation and evaluation of antioxidant activity (in both in vivo and in vitro methods). Moreover, the data from purified compounds and natural extracts are also presented and discussed. Another relevant benefit associated with anthocyanins is their impact on cardiovascular diseases. Chapter 8 presents the main factors associated with the development of cardiovascular diseases and discussed the role of anthocyanins to prevent the progression of this disease. Particular attention is given to the dietary sources of anthocyanins.Reducing the burden of cancer is another pertinent effect related to anthocyanins. In order to disclose the impact of anthocyanins against the development of cancer, Chapter 9 compiles fundamental concepts and scientific data supporting their role against this disease. Particular attention is given to pharmacokinetic of anthocyanins. Additionally, the development of food products for cancer survivors was also included in this chapter.Diabetes is a major disease that imposes limitation in the life of their carriers. Anthocyanins are important dietary components that can induce meaningful effects, at in vitro and in vivo level, to reduce the impact of diabetes in health. This perspective and the scientific data supporting it are discussed in Chapter 10. The inflammatory process is a major response mechanism in the human body. Once this process is dysregulated, a major impairing in health can occur. In Chapter 11, the mechanism by which anthocyanins act as anti-inflammatory compounds on affect key molecules and pathways are described.Neurodegenerative diseases, particularly during aging, are a major concern due to severe limitations related to memory and motion. Chapter 12 is dedicated to disclose the role and mechanisms related to neurodegenerative diseases. Additionally, this chapter also presents the concepts and scientific data regarding the brain bioavailability of anthocyanins. The benefits associated with anthocyanins are not limited to reduce the risk associated with diseases, these compounds are also relevant dietary supplements for athletes. The role on the reduction of oxidative stress and in the performance of athletes and physically active people is discussed in Chapter 13.
Author: Ann Wigmore Publisher: Penguin ISBN: 9780895292346 Category : Health & Fitness Languages : en Pages : 148
Book Description
The Wheatgrass Book is written by Ann Wigmore - the woman who introduced wheatgrass juice to America 30 years ago. Ann's book contains a wealth of information on wheatgrass - from its nutrient properties to ways of easily growing it for the home juicer. Chapters include: green power from wheatgrass, how wheatgrass chlorophyll works, super nutrition from wheatgrass, how to grow and juice wheatgrass and the many uses of wheatgrass. This is a must for the person serious about incorporating wheatgrass into his or her health regimen.
Author: Mohammed Kuddus Publisher: CRC Press ISBN: 1003837980 Category : Technology & Engineering Languages : en Pages : 463
Book Description
Microbial Pigments: Applications in Food and Beverage Industry offers a comprehensive and updated review of the impact of microbial pigments as value-added products in the food and beverage industry. Microbes produce a range of valuable pigments such as carotenoids, flavins, melanins, quinines, and violacein. The book explores the use of microbial pigments as additives, antioxidants, color intensifiers, and functional food ingredients. It discusses pigment isolation and processing technologies. It covers a range of applications across products like jams, spreads, frozen desserts, and beverages. The book also discusses food safety and toxicology aspects. Key features Explores the various microbial pigments and their sources Reviews the pigment isolation, production, and processing techniques Discusses the potential application of pigments across a range of products in the food and beverage industry Includes the latest innovations and patents awarded in use of microbial pigments as value-added food products The book is meant for researchers, academic and industry experts in food biotechnology, food processing, and food microbiology.
Author: Megh R. Goyal Publisher: CRC Press ISBN: 135137642X Category : Science Languages : en Pages : 344
Book Description
This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. It looks at the medicinal properties, antioxidant capacity, and antimicrobial activity of plants and provides scientific evidence on the use of medicinal plants in the treatment of certain diseases. Many of the plants described in the chapters are easily accessible and are believed to be effective with fewer side effects in comparison to modern drugs in the treatment of different diseases.
Author: David R. Katerere Publisher: CRC Press ISBN: 135198179X Category : Medical Languages : en Pages : 339
Book Description
While there is talk of the Fourth Industrial Revolution, old and new challenges bedevil the world – climate change, nutrition, and health poverty being at the top of the list. In seeking solutions to these and other problems which afflict the modern era, it is worthwhile to look into our collective past, to the traditions and knowledges of our ancestors. Such knowledge continues to exist in many parts of the world, though now marginalized by homogenous, Eurocentric ontolology and epistemology. This book presents a compilation of reviews, case studies, and primary research attempting to locate the utility of traditional and Indigenous Knowledges in an increasingly complex world. It assembles chapter authors from across the world to tackle topics ranging from traditional knowledge-based innovations and commercialization, traditional medicine systems as practiced around the world, ethnoveterinary practices, and food innovation to traditional governance and leadership systems, among others. This book is an important resource for policymakers; scholars and researchers of cultural studies, leadership, governance, ethnobotany, anthropology, plant genetic resources and technology innovation; and readers interested in the history of knowledge and culture, as well as cultural activists and political scientists. Features: Unique combination of social science and anthropological aspects with natural science perspectives Includes summaries aimed at policymakers to immediately see what would be relevant to their work Combines case studies illuminating important lessons learned with reviews and primary data Multidisciplinary in the scope of the topics tackled and assemblage of contributors Global footprint with contributions from Africa, Europe, North America, Asia, and the West Indies David R. Katerere, Department of Pharmaceutical Sciences, Tshwane University of Technology, South Africa Wendy Applequist, William L. Brown Center, Missouri Botanical Garden, St Louis, Missouri Oluwaseyi M. Aboyade, Department of Pharmaceutical Sciences, Tshwane University of Technology, South Africa and Nutritica SA, The Innovation Hub, Pretoria, South Africa Chamunorwa Togo, The Innovation Hub, Pretoria, South Africa
Author: POLI Publisher: Birkhäuser ISBN: 3034891164 Category : Science Languages : en Pages : 540
Book Description
Free radical-mediated reactions have been well known in chemistry and physical chemistry for many years. Applying this knowledge to living organisms, biochemists have shown that reactive free radicals are formed at many intracellular sites during normal metabolism, and they have started to suggest possible roles in various pathological processes and conditions, for example in radiation damage, in the metabolism of xenobiotics, in carcinogenesis and in metabolic disorders. At present, a large and relevant mass of experimental evidence supports the view that reactive free radicals are involved in the pathogenesis of several diseases and syndromes. This literature has captured the attention and interest of people involved in the biomedical field. Exciting developments in radical research are probable in the near future, establishing a greater interaction between basic science research and medicine. While the task of defining the involvement of free radicals in human pathology is difficult, it is nonetheless extremely important that such interaction be fulfilled as soon as possible. These were the considerations motivating us during the organization of the VI Biennial Meeting of the International Society for Free Radical Research held in Torino, Italy, in June 1992, and also during the preparation of this book. Experts in the various aspects of free radical research were invited to participate in the Torino Meeting and to contribute chapters for this volume.
Author: Simone Badal McCreath Publisher: Elsevier ISBN: 0443186588 Category : Medical Languages : en Pages : 849
Book Description
Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting. Covers the main sources of natural bioactive substances Contains practice questions and laboratory exercises at the end of every chapter to test learning and retention Describes how pharmacokinetics and pharmacodynamics play a crucial role in discerning the relationships of active metabolites to bioavailability and function at active sites Includes a dedicated chapter on the effect of plant metabolites on SARS-CoV-2
Author: Oluwafemi Oguntibeju
Author: Oluwafemi Oguntibeju
Author: Mallappa Kumara Swamy
Author: Halina Maria Ekiert
Author: José Manuel Lorenzo
Author: Ann Wigmore
Author: Mohammed Kuddus
Author: Megh R. Goyal
Author: David R. Katerere
Author: POLI
Author: Simone Badal McCreath