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Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309391253 Category : Science Languages : en Pages : 327
Book Description
The integrity of knowledge that emerges from research is based on individual and collective adherence to core values of objectivity, honesty, openness, fairness, accountability, and stewardship. Integrity in science means that the organizations in which research is conducted encourage those involved to exemplify these values in every step of the research process. Understanding the dynamics that support â€" or distort â€" practices that uphold the integrity of research by all participants ensures that the research enterprise advances knowledge. The 1992 report Responsible Science: Ensuring the Integrity of the Research Process evaluated issues related to scientific responsibility and the conduct of research. It provided a valuable service in describing and analyzing a very complicated set of issues, and has served as a crucial basis for thinking about research integrity for more than two decades. However, as experience has accumulated with various forms of research misconduct, detrimental research practices, and other forms of misconduct, as subsequent empirical research has revealed more about the nature of scientific misconduct, and because technological and social changes have altered the environment in which science is conducted, it is clear that the framework established more than two decades ago needs to be updated. Responsible Science served as a valuable benchmark to set the context for this most recent analysis and to help guide the committee's thought process. Fostering Integrity in Research identifies best practices in research and recommends practical options for discouraging and addressing research misconduct and detrimental research practices.
Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309391253 Category : Science Languages : en Pages : 327
Book Description
The integrity of knowledge that emerges from research is based on individual and collective adherence to core values of objectivity, honesty, openness, fairness, accountability, and stewardship. Integrity in science means that the organizations in which research is conducted encourage those involved to exemplify these values in every step of the research process. Understanding the dynamics that support â€" or distort â€" practices that uphold the integrity of research by all participants ensures that the research enterprise advances knowledge. The 1992 report Responsible Science: Ensuring the Integrity of the Research Process evaluated issues related to scientific responsibility and the conduct of research. It provided a valuable service in describing and analyzing a very complicated set of issues, and has served as a crucial basis for thinking about research integrity for more than two decades. However, as experience has accumulated with various forms of research misconduct, detrimental research practices, and other forms of misconduct, as subsequent empirical research has revealed more about the nature of scientific misconduct, and because technological and social changes have altered the environment in which science is conducted, it is clear that the framework established more than two decades ago needs to be updated. Responsible Science served as a valuable benchmark to set the context for this most recent analysis and to help guide the committee's thought process. Fostering Integrity in Research identifies best practices in research and recommends practical options for discouraging and addressing research misconduct and detrimental research practices.
Author: Committee on Science, Engineering, and Public Policy (U.S.). Panel on Scientific Responsibility and the Conduct of Research Publisher: National Academies ISBN: Category : Business & Economics Languages : en Pages : 228
Book Description
Responsible Science is a comprehensive review of factors that influence the integrity of the research process. Volume I examines reports on the incidence of misconduct in science and reviews institutional and governmental efforts to handle cases of misconduct. The result of a two-year study by a panel of experts convened by the National Academy of Sciences, this book critically analyzes the impact of today's research environment on the traditional checks and balances that foster integrity in science. Responsible Science is a provocative examination of the role of educational efforts; research guidelines; and the contributions of individual scientists, mentors, and institutional officials in encouraging responsible research practices.
Author: Peter Snyder Publisher: Academic Press ISBN: 0124059295 Category : Science Languages : en Pages : 225
Book Description
The Management of Scientific Integrity within Academic Medical Centers discusses the impact scientific misconduct has in eight complex case studies. Authors look at multifaceted mixtures of improper behavior, poor communication, cultural issues, adverse medical/health issues, interpersonal problems and misunderstandings to illustrate the challenge of identifying and managing what went wrong and how current policies have led to the establishment of quasi legal processes within academic institutions. The book reviews the current global regulations and concludes with a section authored by a US federal court judge who provides his perspective on the adequacy of current regulations and policies. - Shows how complex most scientific integrity cases are, and how little is clear cut in the adjunction of each - Discusses how timely and important scientific misconduct is, and its impact on science at large - Reviews the current regulations and policies that guide how we manage scientific integrity - Examines this complexity in 8 anonymous case studies - Concludes with a section authored by an expertly qualified federal court judge
Author: Elliott C. Kulakowski Publisher: Jones & Bartlett Publishers ISBN: 0763767336 Category : Medical Languages : en Pages : 944
Book Description
This reference text addresses the basic knowledge of research administration and anagement, and includes everything from a review of research administration and the infrastructure that is necessary to support research, to project development and post-project plans. Examples of concepts, case studies, a glossary of terms and acronyms, and references to books, journal articles, monographs, and federal regulations are also included.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309224187 Category : Science Languages : en Pages : 354
Book Description
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Author: Adil E. Shamoo Publisher: Oxford University Press ISBN: 0199709602 Category : Medical Languages : en Pages : 441
Book Description
Recent scandals and controversies, such as data fabrication in federally funded science, data manipulation and distortion in private industry, and human embryonic stem cell research, illustrate the importance of ethics in science. Responsible Conduct of Research, now in a completely updated second edition, provides an introduction to the social, ethical, and legal issues facing scientists today.
Author: Narayanaswamy Balakrishnan Publisher: John Wiley & Sons ISBN: 1118595912 Category : Medical Languages : en Pages : 937
Book Description
A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results. The referenceunveils modern approaches vital to understanding, creating, and evaluating data obtained throughoutthe various stages of clinical trial design and analysis. Accessible and comprehensive, the first volume in a two-part set includes newly-written articles as well as established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: Detailed chapters on the type of trial designs, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials Over 100 contributions from leading academics, researchers, and practitioners An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.
Author: Jordan Richard Schoenherr Publisher: Taylor & Francis ISBN: 1000599043 Category : Computers Languages : en Pages : 227
Book Description
This book offers a unique interdisciplinary perspective on the ethics of 'artificial intelligence' – autonomous, intelligent, (and connected) systems, or AISs, applying principles of social cognition to understand the social and ethical issues associated with the creation, adoption, and implementation of AISs. As humans become entangled in sociotechnical systems defined by human and artificial agents, there is a pressing need to understand how trust is created, used, and abused. Compounding the difficulty in answering these questions, stakeholders directly or indirectly affected by these systems differ in their motivations, understanding, and values. This volume provides a comprehensive resource to help stakeholders understand ethical issues of designing and implementing AISs using an ethical sensemaking approach. Starting with the general technical affordances of AIS, Dr. Jordan Richard Schoenherr considers the features of system design relating data integrity, selection and interpretation of algorithms, and the evolution processes that drive AISs innovation as a sociotechnological system. The poles of technophobia (algorithmic aversion) and technophilia (algorithmic preference) in the public perception of AISs are then described and considered against existing evidence, including issues ranging from the displacement and re-education needs of the human workforce, the impact of use of technology on interpersonal accord, and surveillance and cybersecurity. Ethical frameworks that provide tools for evaluating the values and outcomes of AISs are then reviewed, and how they can be aligned with ethical sensemaking processes identified by psychological science is explored. Finally, these disparate threads are brought together in a design framework. Also including sections on policies and guideline, gaming and social media, and Eastern philosophical frameworks, this is fascinating reading for students and academics in psychology, computer science, philosophy, and related areas, as well as professionals such as policy makers and those working with AI systems.
Author: Thomas O. McGarity Publisher: Harvard University Press ISBN: 0674047141 Category : Law Languages : en Pages : 397
Book Description
What do we know about the possible poisons that industrial technologies leave in our air and water? How reliable is the science that federal regulators and legislators use to protect the public from dangerous products? As this disturbing book shows, ideological or economic attacks on research are part of an extensive pattern of abuse. Thomas O. McGarity and Wendy E. Wagner reveal the range of sophisticated legal and financial tactics political and corporate advocates use to discredit or suppress research on potential human health hazards. Scientists can find their research blocked, or find themselves threatened with financial ruin. Corporations, plaintiff attorneys, think tanks, even government agencies have been caught suppressing or distorting research on the safety of chemical products. With alarming stories drawn from the public record, McGarity and Wagner describe how advocates attempt to bend science or “spin” findings. They reveal an immense range of tools available to shrewd partisans determined to manipulate research. Bending Science exposes an astonishing pattern of corruption and makes a compelling case for reforms to safeguard both the integrity of science and the public health.
Author: National Academies of Sciences, Engineering, and Medicine
Author: National Academies of Sciences, Engineering, and Medicine
Author: Committee on Science, Engineering, and Public Policy (U.S.). Panel on Scientific Responsibility and the Conduct of Research
Author: Peter Snyder
Author: Elliott C. Kulakowski
Author: Institute of Medicine
Author: Nachman Ben-Yehuda
Author: Adil E. Shamoo
Author: Narayanaswamy Balakrishnan
Author: Jordan Richard Schoenherr
Author: Thomas O. McGarity