Analysis of Biomolecules Using Matrix-assisted Laser Desorption/ionization Mass Spectrometry PDF Download

Author: Jennifer Ann Firestine
Publisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 224

View

Book Description

Author: Anissa Wai-Sinn Wong
Publisher:
ISBN:
Category :
Languages : en
Pages : 256

View

Book Description

Author: Michael J. Bogan
Publisher:
ISBN:
Category : Matrix-assisted laser desorption-ionization
Languages : en
Pages : 424

View

Book Description

Author: Steven Travis Fannin
Publisher:
ISBN:
Category :
Languages : en
Pages : 312

View

Book Description

Author: Teresa Catherine Cain
Publisher:
ISBN:
Category :
Languages : en
Pages : 234

View

Book Description

Author: Chau-Wen Chou
Publisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 310

View

Book Description

Author: Mehrnoosh Sadeghi
Publisher:
ISBN:
Category :
Languages : en
Pages : 338

View

Book Description

Author: Bindesh Shrestha
Publisher: Elsevier
ISBN: 0128189991
Category : Science
Languages : en
Pages : 272

View

Book Description
Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules. The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions. Provides the introductory foundations of imaging mass spectrometry for those new to the technique Organized by topic to facilitate a quick deep dive, allowing researchers to immediately apply the imaging MS techniques to their work Includes case studies summarizing the imaging MS techniques developed for the class of molecules

Author: Yan-Hui Liu
Publisher:
ISBN:
Category :
Languages : en
Pages : 460

View

Book Description

Author: M.L Gross
Publisher: Springer Science & Business Media
ISBN: 9401126186
Category : Science
Languages : en
Pages : 462

View

Book Description
The developments in mass spectrometry over the past fifteen years have been impressive in their implications in bioanalytical chemistry. The achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhanced the capabilities for ion trapping especially in analytical mass spectrometry. A major achievement was the development by Barber of Fast Atom Bombardment (FAB) mass spectrometry, an advance that heralded a new era in biological mass spectrometry. Contemporary and routine instruments such as magnetic sectors and quadrupoles were rapidly adapted to F AB, and nearly the entire universe of small molecules became amenable to study by mass spectrometry. The introduction of FAB also paved the way for improvement of instrument capability. For example, the upper mass limit of magnet sector mass spectrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was given new meaning because important structural information for biomolecules could now be produced for ions introduced by FAB into the tandem instrument. The evolution of MS/MS continues today with the development of ion traps, time-of-flight, and sector instruments equipped with array detection.