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Book Description
LE PASSAGE DE L'ADN AUX PROTEINES EST UNE SUCCESSION DE REACTIONS COMPLIQUEES MAIS IL PEUT ETRE DECOMPOSE DE FACON SIMPLE EN DEUX ETAPES PRINCIPALES : LA TRANSCRIPTION, QUI COPIE FIDELEMENT L'INFORMATION CODEE PAR L'ADN EN MOLECULES D'ARN MESSAGER, ET LA TRADUCTION DE CES ARNS MESSAGERS EN PROTEINES. POUR ACTIVER LA TRANSCRIPTION D'UN GENE, DES FACTEURS NOMMES FACTEURS DE TRANSCRIPTION DOIVENT SE FIXER A LEURS PROMOTEURS. NOUS AVONS ETUDIE LES INTERACTIONS ADN - PROTEINE DE DEUX D'ENTRE EUX : REV-ERB ET SRY. D'UNE PART, L'ELEMENT DE REPONSE AUX HORMONES DE REV-ERB , LE 15 MERE REV-RE, A ETE MODELISE EN SE BASANT SUR LES CONTRAINTES OBTENUES PAR RMN. SOUS SA FORME LIBRE, CETTE MOLECULE D'ADN ADOPTE UNE CONFORMATION D'ADN B QUASI CANONIQUE. LES PREMIERES ETUDES SUR LE COMPLEXE REV-ERB - REV-RE MONTRENT QUE D'IMPORTANTES DEFORMATIONS DU DUPLEX D'ADN APPARAISSENT. D'AUTRE PART, LES COMPLEXES SRY-8 MERE ET SRY-14 MERE ONT ETE ANALYSES PAR RMN DU PHOSPHORE ET POUR LA PREMIERE FOIS L'ATTRIBUTION COMPLETE DE TOUS LES SIGNAUX PHOSPHORE DANS UN COMPLEXE ADN - PROTEINE A ETE REALISEE. AU NIVEAU DE L'ETAPE DE TRADUCTION, CHAQUE CODON DE L'ARN MESSAGER EST RECONNU PAR L'ANTICODON EQUIVALENT D'UN ARN DE TRANSFERT CHARGE AVEC L'ACIDE AMINE APPARENTE. LE CHARGEMENT (OU AMINOACYLATION) SPECIFIQUE D'UN ACIDE AMINE SUR SON ARN DE TRANSFERT APPARENTE EST CATALYSE PAR LES AMINOACYL-TRNA SYNTHETASES (AARSS). LA STRUCTURE DU DOMAINE C-TERMINAL DE LA TYROSINE TRNA SYNTHETASE (TYRRS) DE BACILLUS STEAROTHERMOPHILUS EST ETUDIEE PAR RMN HETERONUCLEAIRE ET L'ANALYSE DES SPECTRES TRIDIMENSIONNELLES ( 1 3C- 1 5N- 1H) NOUS A PERMIS D'IDENTIFIER LES ELEMENTS DE STRUCTURE SECONDAIRE QU'UNE ETUDE CRISTALLOGRAPHIQUE N'AVAIT PAS PU REVELER.
Book Description
LE PASSAGE DE L'ADN AUX PROTEINES EST UNE SUCCESSION DE REACTIONS COMPLIQUEES MAIS IL PEUT ETRE DECOMPOSE DE FACON SIMPLE EN DEUX ETAPES PRINCIPALES : LA TRANSCRIPTION, QUI COPIE FIDELEMENT L'INFORMATION CODEE PAR L'ADN EN MOLECULES D'ARN MESSAGER, ET LA TRADUCTION DE CES ARNS MESSAGERS EN PROTEINES. POUR ACTIVER LA TRANSCRIPTION D'UN GENE, DES FACTEURS NOMMES FACTEURS DE TRANSCRIPTION DOIVENT SE FIXER A LEURS PROMOTEURS. NOUS AVONS ETUDIE LES INTERACTIONS ADN - PROTEINE DE DEUX D'ENTRE EUX : REV-ERB ET SRY. D'UNE PART, L'ELEMENT DE REPONSE AUX HORMONES DE REV-ERB , LE 15 MERE REV-RE, A ETE MODELISE EN SE BASANT SUR LES CONTRAINTES OBTENUES PAR RMN. SOUS SA FORME LIBRE, CETTE MOLECULE D'ADN ADOPTE UNE CONFORMATION D'ADN B QUASI CANONIQUE. LES PREMIERES ETUDES SUR LE COMPLEXE REV-ERB - REV-RE MONTRENT QUE D'IMPORTANTES DEFORMATIONS DU DUPLEX D'ADN APPARAISSENT. D'AUTRE PART, LES COMPLEXES SRY-8 MERE ET SRY-14 MERE ONT ETE ANALYSES PAR RMN DU PHOSPHORE ET POUR LA PREMIERE FOIS L'ATTRIBUTION COMPLETE DE TOUS LES SIGNAUX PHOSPHORE DANS UN COMPLEXE ADN - PROTEINE A ETE REALISEE. AU NIVEAU DE L'ETAPE DE TRADUCTION, CHAQUE CODON DE L'ARN MESSAGER EST RECONNU PAR L'ANTICODON EQUIVALENT D'UN ARN DE TRANSFERT CHARGE AVEC L'ACIDE AMINE APPARENTE. LE CHARGEMENT (OU AMINOACYLATION) SPECIFIQUE D'UN ACIDE AMINE SUR SON ARN DE TRANSFERT APPARENTE EST CATALYSE PAR LES AMINOACYL-TRNA SYNTHETASES (AARSS). LA STRUCTURE DU DOMAINE C-TERMINAL DE LA TYROSINE TRNA SYNTHETASE (TYRRS) DE BACILLUS STEAROTHERMOPHILUS EST ETUDIEE PAR RMN HETERONUCLEAIRE ET L'ANALYSE DES SPECTRES TRIDIMENSIONNELLES ( 1 3C- 1 5N- 1H) NOUS A PERMIS D'IDENTIFIER LES ELEMENTS DE STRUCTURE SECONDAIRE QU'UNE ETUDE CRISTALLOGRAPHIQUE N'AVAIT PAS PU REVELER.
Author: Arthur K. Asbury Publisher: Springer Science & Business Media ISBN: 9783211826423 Category : Animal Physiology Languages : en Pages : 228
Book Description
While motor neuropathies and neuronopathies and mixed sensory-motor neuropathies have been met with adequate interest by clinical and basic researchers and physicians, pure sensory neuropathies and neuronopathies have received comparably less attention, despite of the considerable morbidity they may cause in the individual patient. In this volume, a faculty of experienced authorities in the field gives an overview on the physiology, pharmacology, pathology, and clinical signs and symptoms of the sensory nervous system. In addition, specific aspects of morphometry, clinical testing, disease classification, experimental models, and metabolic, infectious and immune-mediated disorders including AIDS are addressed in more detail. The contributions of this volume represent a valuable reference for clinical, physiological, biochemical and pathomorphological studies on the sensory nervous system for which similarly comprehensive data are difficult to locate.
Author: Peter Josef Ell Publisher: ISBN: Category : Nuclear medicine Languages : en Pages : 1100
Book Description
An internationally recognized team of editors and contributors present an authoritative, state-of-the-art reference on nuclear medicine and its clinical applications. They focus on helping the reader to solve the challenges encountered in day-to-day practice, including image interpretation, image optimization techniques, and pitfalls in image acquisition and interpretation. Over 4,400 illustrations, 803 in full color, comprise a comprehensive visual guide to interpretation. This new edition also incorporates three brand-new, full-color atlases-PET and PET/CT, SPECT and SPECT/CT, and a PET brain atlas-as well as many new full-color images (more than 800 in all) Completely revised and thoroughly updated throughout, the 3rd Edition encompasses of all of the latest advances in the diagnostic and therapeutic modalities available for cancer, heart disease, neurologic disorders, and trauma as well as other diseases, both common and rare.
Author: Masaya Segawa Publisher: Parthenon Publishing ISBN: 9781850703723 Category : Medical Languages : en Pages : 230
Book Description
This study examines the condition known as parkinsonism of early onset with diurnal fluctuation (PEDF). It aims to clarify the differences between PEDF and early-onset Parkinson disease, then to compare PEDF with HPD (hereditary progressive dystonia with marked diurnal fluctuation).
Author: Publisher: Academic Press ISBN: 0128172258 Category : Medical Languages : en Pages : 254
Book Description
Mitochondrial Neuropathies, Volume 146, brings together experts in a range of diseases that damage the nervous system to present the role of mitochondrial dysfunction in their particular field, with this new release focusing on Mitochondrial dysfunction in Alzheimer's Disease, HIV and the mitochondrial: immune interface in the CNS, The Impact of mitochondrial damage in HIV-induced peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of chemotherapy-induced peripheral neuropathy, Disorders of mitochondrial biogenesis in peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of diabetic neuropathy, Manipulating mitochondria to treat peripheral neuropathy, and DCA therapy - the yin and yang of mitochondrial activation. - Contains contributions from a diverse group of experts - Presents a timely resource that brings together different fields to highlight a common pathogenic mechanism - Focuses on the role of mitochondria in diverse neuropathies
Author: Melvin DePamphilis Publisher: Garland Science ISBN: 1136738231 Category : Science Languages : en Pages : 476
Book Description
Genome Duplication provides a comprehensive and readable overview of the underlying principles that govern genome duplication in all forms of life, from the simplest cell to the most complex multicellular organism. Using examples from the three domains of life - bacteria, archaea, and eukarya - Genome Duplication shows how all living organisms store their genome as DNA and how they all use the same evolutionary-conserved mechanism to duplicate it: semi-conservative DNA replication by the replication fork. The text shows how the replication fork determines where organisms begin genome duplication, how they produce a complete copy of their genome each time a cell divides, and how they link genome duplication to cell division. Genome Duplication explains how mistakes in genome duplication are associated with genetic disorders and cancer, and how understanding genome duplication, its regulation, and how the mechanisms differ between different forms of life, is critical to the understanding and treatment of human disease.
Author: International Livestock Research Institute Publisher: ILRI (aka ILCA and ILRAD) ISBN: 9789291460038 Category : Animal industry Languages : en Pages : 268
Book Description
Policy concepts; Identification of policy issues; Production systems, supply and demand; Market, price and trade policies; Marketing and distribution systems; Budget and manpower planning; Land tenure police for the livestock sector; Policy analysis report writing and communication; Livestock production and marketing in alphabeta - a case study.
Author: Linda Diann Urden Publisher: Saunders ISBN: Category : Medical Languages : en Pages : 1242
Book Description
Focusing on critical care nursing, this full-color text provides an examination of the important aspects of critical care nursing. It is organized in ten units around alterations in body systems.
Author: CLAIRE.. CASTAGNE
Author: CLAIRE.. CASTAGNE
Author: National Research Council Canada
Author: Arthur K. Asbury
Author: Peter Josef Ell
Author: Masaya Segawa
Author: 
Author: Melvin DePamphilis
Author: International Livestock Research Institute
Author: Linda Diann Urden
Author: J. M. R. Hutchinson