Author: Michel Chevalier
Publisher:
ISBN:
Category : History
Languages : en
Pages : 502
Book Description
Society, Manners and Politics in the United States
Author: Michel Chevalier
Publisher:
ISBN:
Category : History
Languages : en
Pages : 502
Book Description
Publisher:
ISBN:
Category : History
Languages : en
Pages : 502
Book Description
Stem Cells
Author: Department of Health and Human Services
Publisher: CreateSpace
ISBN: 9781492901433
Category : Medical
Languages : en
Pages : 220
Book Description
In February 2001 the Secretary of Health and Human Services requested that the National Institutes of Health prepare a summary report on the state of the science on stem cells. This report was developed in response to his request. It provides the current information about the biology of stem cells derived from all sources—embryo, fetal tissue, and adult. Since 1998, when human pluripotent stem cells were first isolated, research on stem cells has received much public attention, both because of its extraordinary promise and because of relevant legal and ethical issues. Underlying this recent public scrutiny is decades of painstaking work by scientists in many fields, who have been deciphering some of the most fundamental questions about life with the goal of improving health. In the last several decades, investments in basic research have yielded extensive knowledge about the many and complex processes involved in the development of an organism, including the control of cellular development. But many questions remain. How does a single cell—the fertilized egg—give rise to a complex, multi-cellular organism? The question represents a fundamental challenge in developmental biology. Researchers are now seeking to understand in greater detail the genetic factors that regulate cell differentiation in early development. Put simply, stem cells are self-renewing, unspecialized cells that can give rise to multiple types all of specialized cells of the body. The process by which dividing, unspecialized cells are equipped to perform specific functions—muscle contraction or nerve cell communication, for example—is called differentiation, and is fundamental to the development of the mature organism. It is now known that stem cells, in various forms, can be obtained from the embryo, the fetus, and the adult. The report is a review of the state of the science of stem cell research as of June 17, 2001. Included in this report is subject matter addressing stem cells from adult, fetal tissue, and embryonic sources. Because so much of the progress made to date was dependent on animal models, a significant emphasis is placed on understandings gained from mouse models of development and mouse stem cell research. The report also devotes substantial attention to scientific publications on the characterization of specialized cells developed from embryonic stem cells and the plasticity of adult stem cells. Both scientific and lay publications use a variety of terms to describe stem cells and their properties. For this reason, this report adopts a lexicon of terms and it is used consistently throughout. In several places in the report, discovery timelines are provided. The various sources of stem cells are described, as are the techniques used to isolate and develop them. A comprehensive listing of various stem cell isolation and characterizations is also included. In order to ensure the reader is provided information both about the basic biology of stem cells, and their therapeutic potential, the report contains several chapters focused on particular diseases which might benefit from stem cell research. These chapters on the use of hematopoietic stem cells, followed by focus features on specific nervous system diseases, diabetes, heart disease, and autoimmune diseases serve merely as examples of the many applications of stem cells that are being pursued. Also included are features that review aspects of stem cells as therapeutic delivery tools for gene therapy and, importantly, the safety considerations for developing stem cell-based therapies.
Publisher: CreateSpace
ISBN: 9781492901433
Category : Medical
Languages : en
Pages : 220
Book Description
In February 2001 the Secretary of Health and Human Services requested that the National Institutes of Health prepare a summary report on the state of the science on stem cells. This report was developed in response to his request. It provides the current information about the biology of stem cells derived from all sources—embryo, fetal tissue, and adult. Since 1998, when human pluripotent stem cells were first isolated, research on stem cells has received much public attention, both because of its extraordinary promise and because of relevant legal and ethical issues. Underlying this recent public scrutiny is decades of painstaking work by scientists in many fields, who have been deciphering some of the most fundamental questions about life with the goal of improving health. In the last several decades, investments in basic research have yielded extensive knowledge about the many and complex processes involved in the development of an organism, including the control of cellular development. But many questions remain. How does a single cell—the fertilized egg—give rise to a complex, multi-cellular organism? The question represents a fundamental challenge in developmental biology. Researchers are now seeking to understand in greater detail the genetic factors that regulate cell differentiation in early development. Put simply, stem cells are self-renewing, unspecialized cells that can give rise to multiple types all of specialized cells of the body. The process by which dividing, unspecialized cells are equipped to perform specific functions—muscle contraction or nerve cell communication, for example—is called differentiation, and is fundamental to the development of the mature organism. It is now known that stem cells, in various forms, can be obtained from the embryo, the fetus, and the adult. The report is a review of the state of the science of stem cell research as of June 17, 2001. Included in this report is subject matter addressing stem cells from adult, fetal tissue, and embryonic sources. Because so much of the progress made to date was dependent on animal models, a significant emphasis is placed on understandings gained from mouse models of development and mouse stem cell research. The report also devotes substantial attention to scientific publications on the characterization of specialized cells developed from embryonic stem cells and the plasticity of adult stem cells. Both scientific and lay publications use a variety of terms to describe stem cells and their properties. For this reason, this report adopts a lexicon of terms and it is used consistently throughout. In several places in the report, discovery timelines are provided. The various sources of stem cells are described, as are the techniques used to isolate and develop them. A comprehensive listing of various stem cell isolation and characterizations is also included. In order to ensure the reader is provided information both about the basic biology of stem cells, and their therapeutic potential, the report contains several chapters focused on particular diseases which might benefit from stem cell research. These chapters on the use of hematopoietic stem cells, followed by focus features on specific nervous system diseases, diabetes, heart disease, and autoimmune diseases serve merely as examples of the many applications of stem cells that are being pursued. Also included are features that review aspects of stem cells as therapeutic delivery tools for gene therapy and, importantly, the safety considerations for developing stem cell-based therapies.
Data and Goliath: The Hidden Battles to Collect Your Data and Control Your World
Author: Bruce Schneier
Publisher: W. W. Norton & Company
ISBN: 0393244822
Category : Computers
Languages : en
Pages : 299
Book Description
“Bruce Schneier’s amazing book is the best overview of privacy and security ever written.”—Clay Shirky Your cell phone provider tracks your location and knows who’s with you. Your online and in-store purchasing patterns are recorded, and reveal if you're unemployed, sick, or pregnant. Your e-mails and texts expose your intimate and casual friends. Google knows what you’re thinking because it saves your private searches. Facebook can determine your sexual orientation without you ever mentioning it. The powers that surveil us do more than simply store this information. Corporations use surveillance to manipulate not only the news articles and advertisements we each see, but also the prices we’re offered. Governments use surveillance to discriminate, censor, chill free speech, and put people in danger worldwide. And both sides share this information with each other or, even worse, lose it to cybercriminals in huge data breaches. Much of this is voluntary: we cooperate with corporate surveillance because it promises us convenience, and we submit to government surveillance because it promises us protection. The result is a mass surveillance society of our own making. But have we given up more than we’ve gained? In Data and Goliath, security expert Bruce Schneier offers another path, one that values both security and privacy. He brings his bestseller up-to-date with a new preface covering the latest developments, and then shows us exactly what we can do to reform government surveillance programs, shake up surveillance-based business models, and protect our individual privacy. You'll never look at your phone, your computer, your credit cards, or even your car in the same way again.
Publisher: W. W. Norton & Company
ISBN: 0393244822
Category : Computers
Languages : en
Pages : 299
Book Description
“Bruce Schneier’s amazing book is the best overview of privacy and security ever written.”—Clay Shirky Your cell phone provider tracks your location and knows who’s with you. Your online and in-store purchasing patterns are recorded, and reveal if you're unemployed, sick, or pregnant. Your e-mails and texts expose your intimate and casual friends. Google knows what you’re thinking because it saves your private searches. Facebook can determine your sexual orientation without you ever mentioning it. The powers that surveil us do more than simply store this information. Corporations use surveillance to manipulate not only the news articles and advertisements we each see, but also the prices we’re offered. Governments use surveillance to discriminate, censor, chill free speech, and put people in danger worldwide. And both sides share this information with each other or, even worse, lose it to cybercriminals in huge data breaches. Much of this is voluntary: we cooperate with corporate surveillance because it promises us convenience, and we submit to government surveillance because it promises us protection. The result is a mass surveillance society of our own making. But have we given up more than we’ve gained? In Data and Goliath, security expert Bruce Schneier offers another path, one that values both security and privacy. He brings his bestseller up-to-date with a new preface covering the latest developments, and then shows us exactly what we can do to reform government surveillance programs, shake up surveillance-based business models, and protect our individual privacy. You'll never look at your phone, your computer, your credit cards, or even your car in the same way again.
A Frequency Dictionary of Contemporary American English
Author: Mark Davies
Publisher: Routledge
ISBN: 1134008937
Category : Foreign Language Study
Languages : en
Pages : 369
Book Description
First published in 2010 . Routledge is an imprint of Taylor & Francis, an informa company.
Publisher: Routledge
ISBN: 1134008937
Category : Foreign Language Study
Languages : en
Pages : 369
Book Description
First published in 2010 . Routledge is an imprint of Taylor & Francis, an informa company.
Resilience in Aging
Author: Barbara Resnick
Publisher: Springer Science & Business Media
ISBN: 1441902325
Category : Medical
Languages : en
Pages : 372
Book Description
The many significant technological and medical advances of the 21st century cannot overcome the escalating risk posed to older adults by such stressors as pain, weakness, fatigue, depression, anxiety, memory and other cognitive deficits, hearing loss, visual impairment, isolation, marginalization, and physical and mental illness. In order to overcome these and other challenges, and to maintain as high a quality of life as possible, older adults and the professionals who treat them need to promote and develop the capacity for resilience, which is innate in all of us to some degree. The purpose of this book is to provide the current scientific theory, clinical guidelines, and real-world interventions with regard to resilience as a clinical tool. To that end, the book addresses such issues as concepts and operationalization of resilience; relevance of resilience to successful aging; impact of personality and genetics on resilience; relationship between resilience and motivation; relationship between resilience and survival; promoting resilience in long-term care; and the lifespan approach to resilience. By addressing ways in which the hypothetical and theoretical concepts of resilience can be applied in geriatric practice, Resilience in Aging provides inroads to the current knowledge and practice of resilience from the perspectives of physiology, psychology, culture, creativity, and economics. In addition, the book considers the impact of resilience on critical aspects of life for older adults such as policy issues (e.g., nursing home policies, Medicare guidelines), health and wellness, motivation, spirituality, and survival. Following these discussions, the book focuses on interventions that increase resilience. The intervention chapters include case studies and are intended to be useful at the clinical level. The book concludes with a discussion of future directions in optimizing resilience in the elderly and the importance of a lifespan approach to aging.
Publisher: Springer Science & Business Media
ISBN: 1441902325
Category : Medical
Languages : en
Pages : 372
Book Description
The many significant technological and medical advances of the 21st century cannot overcome the escalating risk posed to older adults by such stressors as pain, weakness, fatigue, depression, anxiety, memory and other cognitive deficits, hearing loss, visual impairment, isolation, marginalization, and physical and mental illness. In order to overcome these and other challenges, and to maintain as high a quality of life as possible, older adults and the professionals who treat them need to promote and develop the capacity for resilience, which is innate in all of us to some degree. The purpose of this book is to provide the current scientific theory, clinical guidelines, and real-world interventions with regard to resilience as a clinical tool. To that end, the book addresses such issues as concepts and operationalization of resilience; relevance of resilience to successful aging; impact of personality and genetics on resilience; relationship between resilience and motivation; relationship between resilience and survival; promoting resilience in long-term care; and the lifespan approach to resilience. By addressing ways in which the hypothetical and theoretical concepts of resilience can be applied in geriatric practice, Resilience in Aging provides inroads to the current knowledge and practice of resilience from the perspectives of physiology, psychology, culture, creativity, and economics. In addition, the book considers the impact of resilience on critical aspects of life for older adults such as policy issues (e.g., nursing home policies, Medicare guidelines), health and wellness, motivation, spirituality, and survival. Following these discussions, the book focuses on interventions that increase resilience. The intervention chapters include case studies and are intended to be useful at the clinical level. The book concludes with a discussion of future directions in optimizing resilience in the elderly and the importance of a lifespan approach to aging.
Living with Lead
Author: Bradley D. Snow
Publisher: University of Pittsburgh Press
ISBN: 082298279X
Category : History
Languages : en
Pages : 386
Book Description
The Coeur d'Alenes, a twenty-five by ten mile portion of the Idaho Panhandle, is home to one of the most productive mining districts in world history. Historically the globe's richest silver district and also one of the nation's biggest lead and zinc producers, the Coeur d'Alenes' legacy also includes environmental pollution on an epic scale. For decades local waters were fouled with tailings from the mining district's more than one hundred mines and mills and the air surrounding Kellogg, Idaho was laced with lead and other toxic heavy metals issuing from the Bunker Hill Company's smelter. The same industrial processes that damaged the environment and harmed human health, however, also provided economic sustenance to thousands of local residents and a string of proud, working-class communities. Living with Leadendeavors to untangle the costs and benefits of a century of mining, milling, and smelting in a small western city and the region that surrounds it.
Publisher: University of Pittsburgh Press
ISBN: 082298279X
Category : History
Languages : en
Pages : 386
Book Description
The Coeur d'Alenes, a twenty-five by ten mile portion of the Idaho Panhandle, is home to one of the most productive mining districts in world history. Historically the globe's richest silver district and also one of the nation's biggest lead and zinc producers, the Coeur d'Alenes' legacy also includes environmental pollution on an epic scale. For decades local waters were fouled with tailings from the mining district's more than one hundred mines and mills and the air surrounding Kellogg, Idaho was laced with lead and other toxic heavy metals issuing from the Bunker Hill Company's smelter. The same industrial processes that damaged the environment and harmed human health, however, also provided economic sustenance to thousands of local residents and a string of proud, working-class communities. Living with Leadendeavors to untangle the costs and benefits of a century of mining, milling, and smelting in a small western city and the region that surrounds it.
Traffic Safety Culture
Author: Nicholas John Ward
Publisher: Emerald Group Publishing
ISBN: 1787146170
Category : Transportation
Languages : en
Pages : 364
Book Description
This book provides traffic safety researchers and practitioners with an international and multi-disciplinary compendium of theoretical and methodological concepts relevant to the research and application of Traffic Safety Culture aiming towards a vision of zero traffic fatalities.
Publisher: Emerald Group Publishing
ISBN: 1787146170
Category : Transportation
Languages : en
Pages : 364
Book Description
This book provides traffic safety researchers and practitioners with an international and multi-disciplinary compendium of theoretical and methodological concepts relevant to the research and application of Traffic Safety Culture aiming towards a vision of zero traffic fatalities.
Echoes of Empire
Author: Kalypso Nicolaïdis
Publisher: Bloomsbury Publishing
ISBN: 0857738968
Category : History
Languages : en
Pages : 435
Book Description
How does our colonial past echo through today's global politics? How have former empire-builders sought vindication or atonement, and formerly colonized states reversal or retribution? This groundbreaking book presents a panoramic view of attitudes to empires past and present, seen not only through the hard politics of international power structures but also through the nuances of memory, historiography and national and minority cultural identities. Bringing together leading historians, poitical scientists and international relations scholars from across the globe, Echoes of Empire emphasizes Europe's colonial legacy whilst also highlighting the importance of non-European power centres- Ottoman, Russian, Chinese, Japanese- in shaping world politics, then and now. Echoes of Empire bridges the divide between disciplines to trace the global routes travelled by objects, ideas and people and forms a radically different notion of the term 'empire' itself. This will be an essential companion to courses on international relations and imperial history as well as a fascinating read for anyone interested in Western hegemony, North-South relations, global power shifts and the longue duree.
Publisher: Bloomsbury Publishing
ISBN: 0857738968
Category : History
Languages : en
Pages : 435
Book Description
How does our colonial past echo through today's global politics? How have former empire-builders sought vindication or atonement, and formerly colonized states reversal or retribution? This groundbreaking book presents a panoramic view of attitudes to empires past and present, seen not only through the hard politics of international power structures but also through the nuances of memory, historiography and national and minority cultural identities. Bringing together leading historians, poitical scientists and international relations scholars from across the globe, Echoes of Empire emphasizes Europe's colonial legacy whilst also highlighting the importance of non-European power centres- Ottoman, Russian, Chinese, Japanese- in shaping world politics, then and now. Echoes of Empire bridges the divide between disciplines to trace the global routes travelled by objects, ideas and people and forms a radically different notion of the term 'empire' itself. This will be an essential companion to courses on international relations and imperial history as well as a fascinating read for anyone interested in Western hegemony, North-South relations, global power shifts and the longue duree.
U.S. Industrial Competitiveness
Author: United States. Congress. Office of Technology Assessment
Publisher:
ISBN:
Category : Competition, International
Languages : en
Pages : 220
Book Description
Publisher:
ISBN:
Category : Competition, International
Languages : en
Pages : 220
Book Description
The Persistent Pull of Police Professionalism
Author: David A. Sklansky
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 18
Book Description
"This paper suggests that the past model of police professionalism has been updated as a result of technology and federal funding. Sklansky explains that 1960s police professionalism was not about tactics, such as random patrol, but rather about the governing mindset behind policies. By the early 1980s, this professional policing model was discredited, giving birth to community policing, which also focused more on ideas and policy and less on tactics. Community policing was seen to have shortcomings, such as being vague and not reducing serious crime. Today, professional policing is mounting a comeback. Community policing, however, is still valuable. Although the community policing model is incomplete, a model of "advanced community policing" could address unanswered specifics about the nature of community policing that would help law enforcement agencies, police researchers, and the public resist the persistent pull of police professionalism. Governing Science is one of a series of papers that are being published as a result of the second "Executive Session on Policing and Public Safety," a collaboration of NIJ and Harvard Kennedy School's Program in Criminal Justice Policy and Management."--Publisher's website.
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 18
Book Description
"This paper suggests that the past model of police professionalism has been updated as a result of technology and federal funding. Sklansky explains that 1960s police professionalism was not about tactics, such as random patrol, but rather about the governing mindset behind policies. By the early 1980s, this professional policing model was discredited, giving birth to community policing, which also focused more on ideas and policy and less on tactics. Community policing was seen to have shortcomings, such as being vague and not reducing serious crime. Today, professional policing is mounting a comeback. Community policing, however, is still valuable. Although the community policing model is incomplete, a model of "advanced community policing" could address unanswered specifics about the nature of community policing that would help law enforcement agencies, police researchers, and the public resist the persistent pull of police professionalism. Governing Science is one of a series of papers that are being published as a result of the second "Executive Session on Policing and Public Safety," a collaboration of NIJ and Harvard Kennedy School's Program in Criminal Justice Policy and Management."--Publisher's website.