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Author: V. Zappia Publisher: Springer Science & Business Media ISBN: 1468456377 Category : Science Languages : en Pages : 755
Book Description
This book contains the scientific contributions presented at an International Symposium held in Sorrento, Italy, in June 1988 under the auspices of the University of Naples, the Italian Society of Biochemistry, and the National Research Council. The modern history of polyamines dates back to 1958 when the Tabors and Rosenthal first described the outlines of their biological synthesis. From then on, and particularly in the last ten years, a veri table explosion of Literature, characterized by thousands of papers, has witnessed the interest of the scientific community toward these molecules. Perhaps the old statement that "polyamines are molecules in search of a function" is no longer true today. A large number of effects exerted by these simple molecules are well known, and in many cases the mechanisms underlying these effects have been elucidated. The first section of the volume is entirely devoted to the enzymology and molecular biology of ornithine decarboxylase. Since its discovery by Gale more than forty years ago, this can be considered among the most widely studied enzymes in biology, and one of the most complex models in enzyme regulation. The mechanism of control of the enzyme activity at the transcriptional, post-transcriptional and post-translational levels, as well as the fine regulation by antizyme, are discussed in detail. The second group of contributions deals wi th AdoMet decarboxylase, propylamine transferase, polyamine oxidase and the other enzymes related to polyamine interconversion and regeneration.
Author: V. Zappia Publisher: Springer Science & Business Media ISBN: 1468456377 Category : Science Languages : en Pages : 755
Book Description
This book contains the scientific contributions presented at an International Symposium held in Sorrento, Italy, in June 1988 under the auspices of the University of Naples, the Italian Society of Biochemistry, and the National Research Council. The modern history of polyamines dates back to 1958 when the Tabors and Rosenthal first described the outlines of their biological synthesis. From then on, and particularly in the last ten years, a veri table explosion of Literature, characterized by thousands of papers, has witnessed the interest of the scientific community toward these molecules. Perhaps the old statement that "polyamines are molecules in search of a function" is no longer true today. A large number of effects exerted by these simple molecules are well known, and in many cases the mechanisms underlying these effects have been elucidated. The first section of the volume is entirely devoted to the enzymology and molecular biology of ornithine decarboxylase. Since its discovery by Gale more than forty years ago, this can be considered among the most widely studied enzymes in biology, and one of the most complex models in enzyme regulation. The mechanism of control of the enzyme activity at the transcriptional, post-transcriptional and post-translational levels, as well as the fine regulation by antizyme, are discussed in detail. The second group of contributions deals wi th AdoMet decarboxylase, propylamine transferase, polyamine oxidase and the other enzymes related to polyamine interconversion and regeneration.
Author: Publisher: ScholarlyEditions ISBN: 1464945802 Category : Medical Languages : en Pages : 42
Book Description
Biogenic Polyamines: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Biogenic Polyamines in a compact format. The editors have built Biogenic Polyamines: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biogenic Polyamines in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Biogenic Polyamines: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Publisher: ScholarlyEditions ISBN: 1481615262 Category : Medical Languages : en Pages : 74
Book Description
Biogenic Polyamines—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Biogenic Polyamines in a concise format. The editors have built Biogenic Polyamines—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biogenic Polyamines in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Biogenic Polyamines—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Tomonobu Kusano Publisher: Springer ISBN: 443155212X Category : Science Languages : en Pages : 324
Book Description
This book covers key topics in polyamine research from a range of organisms, including plants, mammals, and prokaryotes such as bacteria and archaea. The book provides an introduction to general concepts in the field of polyamine research, as well as more detailed information. With the availability of genome sequence data from a broad range of organisms, the evolution of the genes involved in polyamine metabolism is discussed. The mode of action of polyamines has been shown to be dependent on cation channels, and this mechanism is described in the book. The origin of polyamine transporters (from bacteria, yeasts, and plants) is described. The various effects of polyamines on growth and survival are also documented. The book details the mechanisms of polyamine homeostasis and the role of polyamine molecules as precursors of secondary metabolites such as plant alkaloids and toxins derived from spiders and wasps. The role of polyamines in longevity and disease is discussed. A link between polyamine contents and cancer progression is reported, as is the use of polyamine metabolites as diagnostic markers in the initial stages of cancer. Moreover, a novel approach that utilizes the polyamine pathway of a parasite as a drug target in African sleeping sickness is described. Therefore, this book is a valuable resource, both as a textbook for undergraduate and graduate students and also as a reference book for front-line polyamine researchers.
Author: V. Zappia
Author: V. Zappia
Author: Advances in Polyamine Research Staff
Author: Robert Allen Campbell
Author: 
Author: L. Selmeci
Author: 
Author: Claudio M. Caldarera
Author: Robert A. Campbell
Author: 
Author: Tomonobu Kusano