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Author: Clayton Fisher Publisher: Foster Academics ISBN: 9781632426970 Category : Medical Languages : en Pages : 255
Book Description
The field of molecular cytogenetics is concerned with the combination of the fields of cytogenetics and molecular biology, to distinguish normal cells from cancer-causing cells. It is a useful tool for the diagnosis and treatment of malignancies of the brain, blood, etc. Novel techniques known as fluorescence in situ hybridization (FISH) are used for molecular cytogenetic studies. These have DNA labeled with uniquely colored fluorescent tags to image specific regions of the genome. Molecular cytogenetic techniques are crucial for the understanding of the structural and functional organization of the nucleus and the chromosome, genome variation, gene expression and evolution. These also give insight into the contribution of genomic variations and chromosomal abnormalities to tumor genetics and medical genetics. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of molecular cytogenetics. It is an upcoming field of science that has undergone rapid development over the past few decades. Students, researchers, experts and all associated with this field will benefit alike from this book.
Author: Clayton Fisher Publisher: Foster Academics ISBN: 9781632426970 Category : Medical Languages : en Pages : 255
Book Description
The field of molecular cytogenetics is concerned with the combination of the fields of cytogenetics and molecular biology, to distinguish normal cells from cancer-causing cells. It is a useful tool for the diagnosis and treatment of malignancies of the brain, blood, etc. Novel techniques known as fluorescence in situ hybridization (FISH) are used for molecular cytogenetic studies. These have DNA labeled with uniquely colored fluorescent tags to image specific regions of the genome. Molecular cytogenetic techniques are crucial for the understanding of the structural and functional organization of the nucleus and the chromosome, genome variation, gene expression and evolution. These also give insight into the contribution of genomic variations and chromosomal abnormalities to tumor genetics and medical genetics. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of molecular cytogenetics. It is an upcoming field of science that has undergone rapid development over the past few decades. Students, researchers, experts and all associated with this field will benefit alike from this book.
Author: James Arthur Birchler Publisher: ISBN: 9783805594943 Category : Plant cytogenetics Languages : en Pages : 0
Book Description
The research reported in this volume illustrates the utility of incorporating cytogenetic tools into biological studies. Somatic chromosome identification is now becoming routine in selected plant species, and the utility of this technique will increase as it expands to other taxa. Individual genes or DNA fragments can be localized to chromosomes in combination with chromosomal identification techniques, which bypasses the need for multiple generations of genetic analysis to map molecular markers to chromosomal positions. The identity of individuals with chromosomal changes can be determined in root tip metaphase spreads, with subsequent growth of these individuals for further genetic and molecular analyses. These new techniques have allowed examination of chromosomal behavior in meiotic and somatic preparations at the whole-genome level. They are also the basis for studies of changes in chromosomal structure or transposable elements in different cells of a single tissue. The studies in this volume illustrate many of these applications and the diversity of research avenues they open up. This publication will be of interest to cytogeneticists, cytologists, cell biologists and evolutionary biologists.
Author: Marcelo B. Cioffi Publisher: S. Karger AG (Switzerland) ISBN: 9783318025286 Category : Fishes Languages : en Pages : 0
Book Description
Fish exhibit the greatest diversity of all vertebrates, making this group extremely attractive for the study of a number of evolutionary questions. Besides, fish genomes have intrinsic characteristics that may be responsible for this amazing diversity, but little is known about their structure and organization. Major advances in chromosomal studies were achieved in the current 'molecular cytogenetic era' based on detecting DNA sequences on chromosomes, parts of chromosomes or even whole genomic DNA by fluorescence in situ hybridization. In this issue, a collection of review articles is presented together with current research results, demonstrating the advances made using this specific methodology in fish research. The contributions provide a timely update on recent developments in fish molecular cytogenetics, covering topics such as karyotype evolution, sex and B chromosomes, polyploids, and molecular evolution. Researchers, teachers, and students interested in the structural features and evolutionary dynamics of fish genomes will find this publication a valuable source of current knowledge.
Author: Marcelo L. Larramendy Publisher: BoD – Books on Demand ISBN: 1839689412 Category : Medical Languages : en Pages : 170
Book Description
This edited book, Cytogenetics - Classical and Molecular Strategies for Analysing Heredity Material, presents recent advances in the field of cytogenetics, paying special attention to methodological achievements developed worldwide that have driven the field forward. The contributors clearly discuss several concepts and approaches useful for understanding chromosomal structure and function at its various levels, highlighting chromosomes as visible carriers of heredity material.
Author: Camila Blair Publisher: American Medical Publishers ISBN: 9781639272464 Category : Medical Languages : en Pages : 233
Book Description
Molecular cytogenetics is a combination of molecular biology and cytogenetics. Molecular biology is a subset of biology that is concerned with the molecular basis of biological activity which occurs between biomolecules in numerous systems of a cell. Cytogenetics, on the other hand, is a field of genetics that deals with how the chromosomes are related to cell behavior during mitosis and meiosis. The aim of molecular cytogenetics is to distinguish between normal and cancer-causing cells using various substances. It is a useful tool for diagnosis and treatment of various malignancies like haematological malignancies, brain tumors, etc. It uses the techniques of fluorescent in situ hybridization and comparative genomic hybridization. This book unravels the recent studies in the field of molecular cytogenetics. It strives to provide a fair idea about this discipline and to help develop a better understanding of the latest advances within this field. Students, researchers, experts and all associated with molecular cytogenetics will benefit alike from this book.
Author: Camila Blair Publisher: American Medical Publishers ISBN: 9781639272570 Category : Medical Languages : en Pages : 233
Book Description
Cytogenetics is a sub-field of genetics that focuses on how the chromosomes are related to cell behavior primarily during mitosis and meiosis. Karyotyping and analysis of G banded chromosomes are the techniques used in cytogenetic binding. Molecular cytogenetics is a domain that includes the combination of molecular biology and cytogenetics. Molecular cytogenetics aims to distinguish between normal and cancer-causing cells using various substances. For the diagnosis and treatment of various malignancies such as hematological malignancies, brain tumors, etc., molecular cytogenetics is one of the most useful tools. Fluorescent in situ hybridization and comparative genomic hybridization are the two kinds of techniques used in molecular cytogenetics. This book provides comprehensive insights into the field of molecular cytogenetics. Different approaches, evaluations, methodologies and advanced studies on molecular cytogenetics have been included herein. This book is a vital tool for all researching or studying this domain as it gives incredible insights into emerging trends and concepts.
Author: Sverre Heim Publisher: John Wiley & Sons ISBN: 1118795539 Category : Medical Languages : en Pages : 642
Book Description
The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible
Author: Sverre Heim Publisher: John Wiley & Sons ISBN: 1118795512 Category : Medical Languages : en Pages : 645
Book Description
The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible
Author: Yasunari Ogihara Publisher: Springer ISBN: 4431556753 Category : Science Languages : en Pages : 445
Book Description
This proceedings is a collection of 46 selected papers that were presented at the 12th International Wheat Genetics Symposium (IWGS). Since the launch of the wheat genome sequencing project in 2005, the arrival of draft genome sequences has marked a new era in wheat genetics and genomics, catalyzing rapid advancement in the field. This book provides a comprehensive review of the forefront of wheat research, across various important topics such as germplasm and genetic diversity, cytogenetics and allopolyploid evolution, genome sequencing, structural and functional genomics, gene function and molecular biology, biotic stress, abiotic stress, grain quality, and classical and molecular breeding. Following an introduction, 9 parts of the book are dedicated to each of these topics. A final, 11th part entitled “Toward Sustainable Wheat Production” contains 7 excellent papers that were presented in the 12th IWGS Special Session supported by the OECD. With rapid population growth and radical climate changes, the world faces a global food crisis and is in need of another Green Revolution to boost yields of wheat and other widely grown staple crops. Although this book focuses on wheat, many of the newly developed techniques and results presented here can be applied to other plant species with large and complex genomes. As such, this volume is highly recommended for all students and researchers in wheat sciences and related plant sciences and for those who are interested in stable food production and food security.
Author: Clayton Fisher
Author: Clayton Fisher
Author: James Arthur Birchler
Author: Marcelo B. Cioffi
Author: Marcelo L. Larramendy
Author: Camila Blair
Author: Camila Blair
Author: Sverre Heim
Author: Sverre Heim
Author: 
Author: Yasunari Ogihara