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Advances in LC-MS Instrumentation

Advances in LC-MS Instrumentation PDF Author: Achille Cappiello
Publisher: Elsevier
ISBN: 0080467989
Category : Science
Languages : en
Pages : 274

Book Description
The different LC-MS techniques available today were developed to suit specific analytical needs and the application range covered by each one is wide, but still limited. GC amenable compounds can be all analyzed with a single GC-MS system whereas HPLC applications call for specific LC-MS instrumental arrangements. ESI, APCI, APPI, and EI are ionization techniques that can be combined with different analyzers, in single or tandem configuration, to create the ultimate system for a certain application. Once approaching LC-MS for a specific need, the fast technical evolution and the variegated commercial offer can induce confusion in the potential user.The role of this book is to enlighten the state-of-the-art of LC-MS evolution through a series of contributions written by the people that brought major, recent innovations in the field. Each chapter will take into consideration the novelties, the advantages and the possible applications covered by a particular technical solution. The book will also include new analytical methods that can provide benefits using the most recent innovations in LC-MS plus a certain number of key applications.- Contains contributions from major innovators in the field- Covers the latest developments in the field of LC-MS- Gives a clear outline on the advantages of various techniques and their applications

Advances in LC-MS Instrumentation

Advances in LC-MS Instrumentation PDF Author: Achille Cappiello
Publisher: Elsevier
ISBN: 0080467989
Category : Science
Languages : en
Pages : 274

Book Description
The different LC-MS techniques available today were developed to suit specific analytical needs and the application range covered by each one is wide, but still limited. GC amenable compounds can be all analyzed with a single GC-MS system whereas HPLC applications call for specific LC-MS instrumental arrangements. ESI, APCI, APPI, and EI are ionization techniques that can be combined with different analyzers, in single or tandem configuration, to create the ultimate system for a certain application. Once approaching LC-MS for a specific need, the fast technical evolution and the variegated commercial offer can induce confusion in the potential user.The role of this book is to enlighten the state-of-the-art of LC-MS evolution through a series of contributions written by the people that brought major, recent innovations in the field. Each chapter will take into consideration the novelties, the advantages and the possible applications covered by a particular technical solution. The book will also include new analytical methods that can provide benefits using the most recent innovations in LC-MS plus a certain number of key applications.- Contains contributions from major innovators in the field- Covers the latest developments in the field of LC-MS- Gives a clear outline on the advantages of various techniques and their applications

The Encyclopedia of Mass Spectrometry

The Encyclopedia of Mass Spectrometry PDF Author:
Publisher: Newnes
ISBN: 0080913253
Category : Science
Languages : en
Pages : 407

Book Description
Volume 9: Historical Perspectives, Part A: The Development of Mass Spectrometry of The Encyclopedia of Mass Spectrometry describes and analyzes the development of many aspects of Mass Spectrometry. Beginning with the earliest types of Mass Analyzers, Historical Perspectives explores the development of many different forms of analytical processes and methods. The work follows various instruments and interfaces, to the current state of detectors and computerization. It traces the use of Mass Spectrometry across many different disciplines, including Organic Chemistry, Biochemistry, and Proteomics; Environmental Mass Spectrometry; Forensic Science; Imaging; Medical Monitoring and Diagnosis; Earth and Planetary Sciences; and Nuclear Science. Finally, the book covers the history of manufacturers and societies as well as the professionals who form the Mass Spectrometry community. Also available: Volume 9: Historical Perspectives, Part B: Notable People in Mass Spectrometry briefly reviews the lives and works of many of the major people who carried out this development. Preserves the history and development of Mass Spectrometry for use across scientific fields Written and edited by Mass Spectrometry experts Coordinates with Volume 9: Historical Perspectives, Part B: Notable People in Mass Spectrometry, a collection of short biographies on many of the major people who carried out this development

Advances in Mass Spectrometry, Volume 12

Advances in Mass Spectrometry, Volume 12 PDF Author: P.G. Kistemaker
Publisher: Elsevier
ISBN: 0444599452
Category : Science
Languages : en
Pages : 975

Book Description
These proceedings, containing the texts of the invited lectures, cover all aspects of mass spectrometry including theory, fundamental studies, applications and instrumentation. Emphasis is placed on recent developments. A complete listing of the posters is included.

Ambient Ionization Mass Spectrometry

Ambient Ionization Mass Spectrometry PDF Author: Marek Domin
Publisher: Royal Society of Chemistry
ISBN: 1849739269
Category : Science
Languages : en
Pages : 528

Book Description
Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.

Fundamentals of Contemporary Mass Spectrometry

Fundamentals of Contemporary Mass Spectrometry PDF Author: Chhabil Dass
Publisher: John Wiley & Sons
ISBN: 0470118482
Category : Science
Languages : en
Pages : 512

Book Description
Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.

Advanced Techniques in Gas Chromatography-Mass Spectrometry (GC-MS-MS and GC-TOF-MS) for Environmental Chemistry

Advanced Techniques in Gas Chromatography-Mass Spectrometry (GC-MS-MS and GC-TOF-MS) for Environmental Chemistry PDF Author:
Publisher: Newnes
ISBN: 0444626247
Category : Science
Languages : en
Pages : 525

Book Description
Gas chromatography mass spectrometry (GC-MS) has been the technique of choice of analytical scientists for many years. The latest developments in instrumentation, including tandem mass spectrometry (MS-MS) and time-of-flight (TOF) detectors, have opened up and broadened the scope of environmental analytical chemistry. This book summarizes the major advances and relevant applications of GC-MS techniques over the last 10 years, with chapters by leading authors in the field of environmental chemistry. The authors are drawn from academia, industry and government. The book is organized in three main parts. Part I covers applications of basic GC-MS to solve environmental-related problems. Part II focuses on GC-MS-MS instrumentation for the analyses of a broad range of analysis in environmental samples (pesticides, persistent organic pollutants, endocrine disruptors, etc.). Part III covers the use of more advanced GC-MS techniques using low- and high-resolution mass spectrometry for many applications related to the environment, food and industry. - Summarizes the major advances of GC-MS techniques in the last decade - Presents relevant applications of GC-MS techniques - Covers academic, industrial and governmental sectors

Advances in Mass Spectrometry

Advances in Mass Spectrometry PDF Author: R. M. Elliott
Publisher: Elsevier
ISBN: 1483149447
Category : Science
Languages : en
Pages : 647

Book Description
Advances in Mass Spectrometry, Volume 2 documents the proceedings of a conference on mass spectrometry held in Oxford in September 1961. This compilation is categorized into six major topics — mass spectrometry in research; mass spectrometry of inorganic compounds; instruments and techniques; theory and correlation of mass spectra; mass spectra and analysis; and ionization and dissociation. Under these major topics, parts of the papers discussed include field ionization mass spectroscopy; initial kinetic energy discrimination effects in crossed-field ion sources; mass spectrometric study of CaO and Ta; and spark source mass spectrometry as an analytical technique. The book also covers discussions on initial energy of hydrocarbon fragment ions; determination of the structure of alkaloids by mass spectrometry; and application of a time-of-flight mass spectrometer to the examination of ion-molecule interactions. This volume is a useful reference to students and researchers conducting work on mass spectrometry.

Ion Mobility-Mass Spectrometry

Ion Mobility-Mass Spectrometry PDF Author: Alison E Ashcroft
Publisher: Royal Society of Chemistry
ISBN: 1839162899
Category : Science
Languages : en
Pages : 621

Book Description
Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.

Plasma Source Mass Spectrometry

Plasma Source Mass Spectrometry PDF Author: Scott D Tanner
Publisher: Royal Society of Chemistry
ISBN: 1847551696
Category : Science
Languages : en
Pages : 440

Book Description
The understanding of the principles of ICP-MS and its application as an analytical technique is continually evolving and this book provides a unique snapshot of the current state-of-the-art. Plasma Source Mass Spectrometry: The New Millennium covers a diverse range of topics including the fate of the sample as it passes through the sample introduction system, chemical resolution using reaction and collision cells, various methods of mass analysis, approaches to account for spectral interferences, hyphenation methods to enable speciation, and the results of analyses ranging from natural waters and archaeological isotope ratios to organometallic speciation in biological materials. Describing explicitly the analytical methods that deal with current analytical challenges, and offering a current perspective on elemental analysis by plasma source mass spectrometry that is not to be found elsewhere, this book will be welcomed by both academics and industrialists as containing the most up-to-date information available on this burgeoning topic.

Mass Spectrometry of Inorganic and Organometallic Compounds

Mass Spectrometry of Inorganic and Organometallic Compounds PDF Author: William Henderson
Publisher: John Wiley & Sons
ISBN: 047001430X
Category : Science
Languages : en
Pages : 272

Book Description
This is the first modern book to treat inorganic and organometallic mass spectrometry simultaneously. It is textbook and handbook in one; as a textbook it introduces the techniques and gives hints on how to apply the various techniques, as a handbook it lists all available ionization techniques for just about any given compound. The book also includes non-mathematical explanations of how modern MS instruments work Mass Spectrometry of Inorganic and Organometallic Compounds will inspire the synthetic inorganic and organometallic chemist with the confidence to apply some of the new techniques to their characterization problems.