Advancement and New Understanding in Brain Injury PDF Download

Author: Zamzuri Idris
Publisher: BoD – Books on Demand
ISBN: 1838819193
Category : Medical
Languages : en
Pages : 218

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Book Description
This book covers the latest developments in the understanding and treatment of traumatic brain injury. Various world experts authored the chapters that comprise a wealth of updated information on intracranial pressure; monitoring and diagnostic methods; neuroinflammatory responses in traumatic brain injury; cerebral palsy and Covid-19–related brain disorder; pathogenesis and prevention of fetal, neonatal, infant, and child brain injury; hyperbaric oxygenation treatment; the engineering and modeling of head injury; systematic review on early-tracheostomy; intracranial aneurysm in tuberous sclerosis complex; and the neurobehavioral and cognitive aspects of brain injury. With these complex topics, every clinician, scientist, and researcher will find this book invaluable in understanding the latest improvements and advances in the diagnosis and treatment of traumatic brain injury.

Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 388

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Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Author: Harvey Levin
Publisher: Oxford University Press
ISBN: 0199389632
Category : Psychology
Languages : en
Pages : 486

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Book Description
This timely book reports recent progress in research on traumatic brain injury (TBI) by leading investigators encompassing translational and clinical studies. The text covers epidemiology, pathophysiology, brain imaging, cognition, behavioral sequelae, and clinical trials of innovative treatments, including new approaches to rehabilitation. The range of TBI mechanisms represented in this cutting-edge book includes closed head trauma and blast-related injury, and the spectrum of TBI severity. Chapters offer a developmental perspective, including the effects of TBI on cognitive development in children and outcome studies in adults. Contributors from various countries provide a global perspective on this worldwide health problem. The editors have synthesized the contents in a concluding chapter. Researchers and clinicians will find this volume to be an informative, authoritative reference for current TBI research.

Author: A. Baethmann
Publisher: Springer Science & Business Media
ISBN: 1468452037
Category : Science
Languages : en
Pages : 403

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Book Description
A distinction between primary and secondary brain damage of vari ous origin, particularly in acute lesions, such as head injury and ische mia is not entirely new. The concept is of practical significance, be cause it is the foremost intention of all clinical efforts to prevent, or at least attenuate the development of secondary sequelae. Primary dam age to nervous elements usually cannot be influenced by treatment. Its prevention is the objective of prophylactic measures. The current volume gathered prominent scientists and clinicians from various fields to pro vide a competent introduction and survey of the various aspects involved in secondary brain damage. It was attempted to provide criteria for the distinction between the primary and secondary phenomena on a morpho logical and functional level, on the basis of the kinetics involved and, most importantly, regarding the different specific manifestations, such as disturbances of microcirculation, aspects of the blood-brain barrier, and of cellular structure and function at a molecular level. Although it was not expected that a grand unifying hypothesis will be reached recon cilable with the many, occasionally opposing views on such a complex subject, nevertheless, the present volume attains an appropriate result. It can best be described as a mosaic of many different pieces which only as an ensemble reflect the current state of the art.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486890
Category : Medical
Languages : en
Pages : 211

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Book Description
The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.

Author: A. Baethmann
Publisher: Springer Science & Business Media
ISBN: 3709163919
Category : Medical
Languages : en
Pages : 136

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Book Description
Information is provided from the basic and clinical sciences on the mechanisms damaging the brain from trauma or ischemia. New aspects involve the endoplasmic reticulum, mitochondrial failure, pathobiology of axonal injury, molecular signals activating glial elements, or the emerging therapeutical role of neurotrophins. Experimental issues involve a better analysis of the ischemic penumbra, the salvagable tissue. Therapeutic contributions reach from the environmental influence to gene expression, including neuroprotection, such as hibernation – mother nature’s experiment – or hypothermia which is reported to induce cell swelling. Treatment issues deal also with thrombolysis and combination therapies, or with the clearance of adverse blood components – LDL/fibrinogen – by a novel procedure using heparin. Other highlights are discussing the specificities of pediatric vs. adult brain trauma, or the evolving role of the Apolipoprotein-E e4 gene in severe head injury. An update is also provided on an online assessment of the patient management during the pre- and early hospital phase in Southern Bavaria. The empirical observation of neuroworsening is analyzed in further details, whether this is a specificity autonomously driving the posttraumatic course. Finally, the unsolved question why drug trials in severe head injury have failed so far in view of the promising evidence from the laboratory is subjected to an expert analysis.

Author: Firas H. Kobeissy
Publisher: CRC Press
ISBN: 1466565993
Category : Medical
Languages : en
Pages : 718

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Book Description
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Author: A. Baethmann
Publisher: Springer Science & Business Media
ISBN: 3709106036
Category : Medical
Languages : en
Pages : 126

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Book Description
Top level clinical and laboratory scientists present their most recent clinical and experimental findings and concepts. The well balanced contributions illustrate the enormous significance of the dialogue between both laboratory and clinic, ultimately for the benefit of the patients, and contribute to a better understanding of secondary brain damage from trauma and ischemia as basis to develop more effective treatment including drugs.

Author: Zhou Zhou
Publisher: Frontiers Media SA
ISBN: 2832551084
Category : Medical
Languages : en
Pages : 140

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Book Description
Traumatic brain injury (TBI) remains one of healthcare's most significant challenges and policy making. TBI could not only lead to long-term functional impairment but also a decrease in quality of life. Lowering the mortality risk and benefitting survivors' living quality remains the target of neurotrauma studies globally. With the advent of novel TBI-related clinical and basic research approaches, diagnostics, therapeutics research, and novel and multidisciplinary methods have emerged. Despite promising progress, no completely effective treatment prevents or minimizes TBI and its related neurological and psychiatric sequelae. Understanding the mechanisms underlying the pathophysiology, treatment progress, and clinically based translational and engineering research on TBI may pave the way for potential treatment targets, diagnostic markers, and preventive methods that ultimately lead to efficacious therapeutic strategies. This Research Topic aims to disseminate high-quality TBI and related research, especially for the compositive and in-depth study in integration, translation, and multidisciplinary approaches in TBI research, including new technology and research methods in clinical neurology, new findings in neuroendocrinology, neuropathology and new development in neuropharmacology, neurophysiology. This Research Topic is focused on novel developments, current challenges, future perspectives, and especially interdisciplinary research in the field of TBI.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher:
ISBN: 9780309490436
Category :
Languages : en
Pages : 244

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Book Description
Every community is affected by traumatic brain injury (TBI). Causes as diverse as falls, sports injuries, vehicle collisions, domestic violence, and military incidents can result in injuries across a spectrum of severity and age groups. Just as the many causes of TBI and the people who experience it are diverse, so too are the physiological, cognitive, and behavioral changes that can occur following injury. The overall TBI ecosystem is not limited to healthcare and research, but includes the related systems that administer and finance healthcare, accredit care facilities, and provide regulatory approval and oversight of products and therapies. TBI also intersects with the wide range of community organizations and institutions in which people return to learning, work, and play, including the education system, work environments, professional and amateur sports associations, the criminal justice system, and others. Traumatic Brain Injury: A Roadmap for Accelerating Progress examines the current landscape of basic, translational, and clinical TBI research and identifies gaps and opportunities to accelerate research progress and improve care with a focus on the biological, psychological, sociological, and ecological impacts. This report calls not merely for improvement, but for a transformation of attitudes, understanding, investments, and care systems for TBI.