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Author: Dr. Pradeep Kumar M. R. Publisher: Insta Publishing ISBN: 9395037679 Category : Literary Criticism Languages : en Pages : 164
Book Description
: Pharmaceutical organic chemistry is an important part of Pharmaceutical Research and Development unit, since it involves preparation of novel or modification of already existing molecules to extract the therapeutic application of these molecules. This book deals with different types of experiments, where the major emphasis is given on various basic techniques of Organic chemistry like melting point, boiling point, crystallization, distillation, and calibration of thermometer. It also includes identification of organic compound of various functional groups from carboxylic acid, Phenols, ketons, aldehyde….etc, with specific reaction procedure and its chemical reaction. It also covers experimental methods consisting of the derivatives preparations of functional groups. The book also covers some Organic preparation /Synthesis of compounds with reaction, principle and mechanism These experiments are selected in such a manner that the reader should get a in depth knowledge about the medicinal chemistry practicals. All comments and suggestions will be received with gratitude. I am very much grateful to KLE Academy of Higher Education and Research, all my beloved teachers, parents, wife for their constant support and encouragement. Thanks to my daughters Ananya and Adhya, who are my stress relievers. I would like to express my heartfelt thanks to each and everyone who directly or indirectly helped me in compilation of this book Last but not the least I am very much thankful to all my students who are the inspiration for writing this book.
Author: Dr. Pradeep Kumar M. R. Publisher: Insta Publishing ISBN: 9395037679 Category : Literary Criticism Languages : en Pages : 164
Book Description
: Pharmaceutical organic chemistry is an important part of Pharmaceutical Research and Development unit, since it involves preparation of novel or modification of already existing molecules to extract the therapeutic application of these molecules. This book deals with different types of experiments, where the major emphasis is given on various basic techniques of Organic chemistry like melting point, boiling point, crystallization, distillation, and calibration of thermometer. It also includes identification of organic compound of various functional groups from carboxylic acid, Phenols, ketons, aldehyde….etc, with specific reaction procedure and its chemical reaction. It also covers experimental methods consisting of the derivatives preparations of functional groups. The book also covers some Organic preparation /Synthesis of compounds with reaction, principle and mechanism These experiments are selected in such a manner that the reader should get a in depth knowledge about the medicinal chemistry practicals. All comments and suggestions will be received with gratitude. I am very much grateful to KLE Academy of Higher Education and Research, all my beloved teachers, parents, wife for their constant support and encouragement. Thanks to my daughters Ananya and Adhya, who are my stress relievers. I would like to express my heartfelt thanks to each and everyone who directly or indirectly helped me in compilation of this book Last but not the least I am very much thankful to all my students who are the inspiration for writing this book.
Author: Stéphane Caron Publisher: John Wiley & Sons ISBN: 1118093569 Category : Science Languages : en Pages : 870
Book Description
A hands-on guide to assist in the planning and execution of synthetic reactions in the laboratory Despite the maturity of organic chemistry, it can still be very challenging to identify optimal methods for synthetic transformations that perform as well in real-world manufacturing processes as they do in the laboratory. This detailed and accessible guide attempts to address this vexing issue and deliver proven methodologies practicing synthetic chemists will find valuable for identifying reaction conditions that work reliably over the broadest possible range of substrates. Practical Synthetic Organic Chemistry: Provides a practical guide to strategically planning and executing chemical syntheses for the bench chemist in industry Discusses information that is not common knowledge beyond the boundaries of process chemistry groups, such as the synthetic routes of selected contemporary pharmaceutical drugs and practical solvents, as well as green chemistry concepts Highlights key reactions, including substitutions, additions, eliminations, rearrangements, oxidations, and reductions Addresses basic principles, mechanisms, advantages and disadvantages of the methodology, and techniques for achieving laboratory success Incorporating such an extraordinary wealth of information on organic chemistry and its related fields into one complete volume distinguishes Practical Synthetic Organic Chemistry as an incomparable desktop reference for professionals and an invaluable study aid for students.
Author: Stéphane Caron Publisher: John Wiley & Sons ISBN: 1119448859 Category : Science Languages : de Pages : 850
Book Description
This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale
Author: V. Alagarsamy Publisher: BSP Books ISBN: 9389354781 Category : Science Languages : en Pages : 1323
Book Description
Pharmaceutical organic chemistry is the main branch of organic chemistry deals with the study of preparation, structure and reactions of organic compounds. As it deals with all the chemical reactions related to life, study of Pharmaceutical organic chemistry is important. Application of Organic chemistry in the development of pharmaceuticals, resulted in evolving Pharmaceutical organic chemistry. Hence studying Organic chemistry and applying this knowledge in Pharmaceutical substances is called as Pharmaceutical organic chemistry. Organic chemistry forms the basis of biochemistry, in which various aspects of health and diseases are studied. The biochemical knowledge is very important for the practice of nutritional, medical and related life sciences. In addition Organic chemistry paved way for the development of medicinal chemistry, Pharmaceutical organic chemistry, bioinformatics, biotechnology, gene therapy, Pharmacology, pathology, chemical engineering, dental science and so on. Organic substances play such a vital role in our daily life that all of us should know about organic chemistry in order to understand the manner how it influence our life process.
Author: Patrick E. McMahon Publisher: CRC Press ISBN: 1351848224 Category : Medical Languages : en Pages : 821
Book Description
Reviews key general chemistry concepts and techniques, adapted for application to important organic principles Provides practical guidance to help students make the notoriously well-known and arduous transition from general chemistry to organic chemistry Explains organic concepts and reaction mechanisms, generally expanding the focus on how to understand each step from a more intuitive viewpoint Covers concepts that need further explanation as well as those that summarize and emphasize key ideas or skills necessary in this field. An added bonus is help with organizing principles to make sense of a wide range of similar reactions and mechanisms Implements a user-friendly process to achieve the end result of problem solving Covers organic chemistry I and II concepts at the level and depth of a standard ACS organic chemistry curriculum; features practice problems and solutions to help master the material, including an extensive and comprehensive bank of practice exams with solutions
Author: Rama Rao Nadendla Publisher: Macmillan ISBN: 9781403924957 Category : Chemistry, Organic Languages : en Pages : 440
Book Description
This book delves into all major concepts in organic pharmaceuticals, includes all the changes, modifications and revisions made to the syllabi of various Indian universities catering to needs of undergraduate students of pharmacy and science. The book co
Author: Andrew Davis Publisher: Royal Society of Chemistry ISBN: 1782621830 Category : Science Languages : en Pages : 789
Book Description
Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.
Author: Camille Georges Wermuth Publisher: Elsevier ISBN: 012417213X Category : Science Languages : en Pages : 903
Book Description
The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. - Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field - Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts - Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research - An image bank is available for instructors at www.textbooks.elsevier.com
Author: Paul M. Dewick Publisher: John Wiley & Sons ISBN: 1118681967 Category : Science Languages : en Pages : 711
Book Description
Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.
Author: Neal G. Anderson Publisher: Academic Press ISBN: 9781483299778 Category : Science Languages : en Pages : 354
Book Description
This book provides a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more * Includes over 100 tips for rapid process development * Presents guidelines for implementing and troubleshooting processes
Author: Dr. Pradeep Kumar M. R.
Author: Dr. Pradeep Kumar M. R.
Author: Stéphane Caron
Author: Stéphane Caron
Author: V. Alagarsamy
Author: Patrick E. McMahon
Author: Rama Rao Nadendla
Author: Andrew Davis
Author: Camille Georges Wermuth
Author: Paul M. Dewick
Author: Neal G. Anderson