A second Letter to ... C. J. F. upon the dangerous and inflammatory tendency of his late conduct in Parliament: in which the principles, the duties and the composition of minorities are particularly considered. By the author of the first letter PDF Download

Author: Charles James Fox
Publisher:
ISBN:
Category :
Languages : en
Pages : 76

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Author: British Museum. Department of Printed Books
Publisher:
ISBN:
Category : English literature
Languages : en
Pages : 1028

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Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 720

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Author: British Museum. Department of Printed Books
Publisher:
ISBN:
Category : English literature
Languages : en
Pages : 864

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Author: British museum. Dept. of printed books
Publisher:
ISBN:
Category :
Languages : en
Pages : 424

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Author: British Museum. Dept. of Printed Books
Publisher:
ISBN:
Category : English imprints
Languages : en
Pages : 1312

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Author: World Health Organization
Publisher:
ISBN: 9789290360742
Category : Medical
Languages : en
Pages : 381

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Book Description
In spite of recent progress in the harmonization of terminology and processes affecting work on the clinical safety of medicines consensus is needed on standards for many difficult aspects of day-to-day pharmacovigilance that continue to pose problems for both the pharmaceutical industry and drug regulators. The CIOMS V Working Group has generated proposals for pragmatic approaches to dealing with such issues as: classification and handling of individual safety case reports from a variety of sources (spontaneous consumer reports solicited reports literature the Internet observational studies and secondary data bases disease and other registries regulatory ADR databases and licensor-licensee interactions); new approaches to case management and regulatory reporting practices (proper clinical evaluation of cases incidental vs other events patient and reporter identifiability seriousness criteria expectedness criteria case follow-up criteria and the role and structure of case narratives); improvements and efficiencies in the format content and reporting of periodic safety update reports (PSURs) (including results of an industry survey on PSUR workloads and practices; proposals for high case volume and long time-period reports simplification of certain PSURs summary bridging reports addendum reports license renewal reports for EU and Japan dealing with old products and other technical details); determination and use of population exposure (denominator) data (sources of data and a guide to analytical approaches for a variety of circumstances).The Group has also taken stock of the current state of expedited and periodic clinical safety reporting requirements around the world with summary data on regulations from more than 60 countries. Recommendations are made for enhancing the harmonization steps already taken as a result of previous CIOMS publications and the ICH process. In addition to dealing with unfinished and unresolved issues from previous CIOMS initiatives the report covers many emerging topics such as those involving new technologies. Its 20 Appendices provide a wealth of detailed explanations and reference information. It is the most comprehensive and recent treatment of difficult pharmacovigilance issues affecting the working practices and systems of drug safety and other pharmaceutical professionals.

Author: MacKinnon, Rebecca
Publisher: UNESCO Publishing
ISBN: 923100039X
Category : Education
Languages : en
Pages : 211

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Internet intermediaries play a unique role in linking authors of content and audiences. They may either protect or jeopardize end user rights to free expression, given their role in capturing, storing, searching, sharing, transferring and processing large amount of information, data and user-generated content. This research aims to identify principles for good practices and processes that are consistent with international standards for free expression that Internet intermediaries may follow in order to protect the human rights of end users online.

Author: Gordon Waddell
Publisher:
ISBN: 9780117038615
Category : Vocational rehabilitation
Languages : en
Pages : 307

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The aim of this review was to provide an evidence base for policy development on vocational rehabilitation - defined as whatever helps someone with a health problem to stay at, return to and remain at work. The focus was on adults of working age, the common health problems that account for two-thirds of long-term sickness (mild/moderate musculoskeletal, mental health and cardio-respiratory conditions) and work outcomes (staying at, returning to and remaining in work). Data from some 450 scientific reviews and reports were included in evidence tables. The review demonstrates that there is a strong scientific evidence base for many aspects of vocational rehabilitation, a good business case for it and more evidence on cost-benefits than for many health and social policy areas. Generic and condition-specific findings are reported, and practical suggestions offered for the differing types of people affected by health problems. Vocational rehabilitation should be a fundamental element of government strategy to improve the health of working age people.

Author: R.D. Semba
Publisher: Karger Medical and Scientific Publishers
ISBN: 331802189X
Category : Medical
Languages : en
Pages : 224

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Book Description
This book shows how vitamin A deficiency – before the vitamin was known to scientists – affected millions of people throughout history. It is a story of sailors and soldiers, penniless mothers, orphaned infants, and young children left susceptible to blindness and fatal infections. We also glimpse the fortunate ones who, with ample vitamin A-rich food, escaped this elusive stalker. Why were people going blind and dying? To unravel this puzzle, scientists around the world competed over the course of a century. Their persistent efforts led to the identification of vitamin A and its essential role in health. As a primary focus of today’s international public health efforts, vitamin A has saved hundreds of thousands of lives. But, we discover, they could save many more were it not for obstacles erected by political and ideological zealots who lack a historical perspective of the problem. Although exhaustively researched and documented, this book is written for intellectually curious lay readers as well as for specialists. Public health professionals, nutritionists, and historians of science and medicine have much to learn from this book about the cultural and scientific origins of their disciplines. Likewise, readers interested in military and cultural history will learn about the interaction of health, society, science, and politics. The author’s presentation of vitamin A deficiency is likely to become a classic case study of health disparities in the past as well as the present.