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A Polymer Cochlear Electrode Array: Atraumatic Deep Insertion, Tripolar Stimulation, and Long-Term Reliability

A Polymer Cochlear Electrode Array: Atraumatic Deep Insertion, Tripolar Stimulation, and Long-Term Reliability PDF Author: Tae Mok Gwon
Publisher: Springer
ISBN: 9811304726
Category : Technology & Engineering
Languages : en
Pages : 107

Book Description
This book describes the design, fabrication and evaluation of a polymer-based neural interface for a cochlear electrode array, reviewed in terms of fabrication process, functionality, and reliability. Polymer-based devices have attracted attention in the neural prosthetic field due to their flexibility and compatibility with micro-fabrication process. A liquid crystal polymer (LCP) is an inert, highly water-resistant polymer suitable for the encapsulation of electronic components and as a substrate material for fabricating neural interfaces. The author has designed, fabricated, and evaluated an LCP-based cochlear electrode array for an improved polymer-based cochlear implant. The thesis deals with 3 key topics: atraumatic deep insertion, tripolar stimulation, and long-term reliability. Atraumatic insertion of the intracochlear electrode and resulting preservation of residual hearing have become essential in state–of-the-art cochlear implantation. A novel tapered design of an LCP-based cochlear electrode array is presented to meet such goals. For high-density and pitch-recognizable cochlear implant, channel interaction should be avoided. Local tripolar stimulation using multi-layered electrode sites are shown to achieve highly focused electrical stimulation. This thesis addresses another vital issue in the polymer-based neural implants: the long-term reliability issue. After suggesting a new method of forming mechanical interlocking to improve polymer-metal adhesion, the author performs accelerating aging tests to verify the method’s efficacy. The aforementioned three topics have been thoroughly examined through various in vitro and in vivo studies. Verification foresees the development of LCP-based cochlear electrode array for an atraumatic deep insertion, advanced stimulation, and long-term clinical implant.

A Polymer Cochlear Electrode Array: Atraumatic Deep Insertion, Tripolar Stimulation, and Long-Term Reliability

A Polymer Cochlear Electrode Array: Atraumatic Deep Insertion, Tripolar Stimulation, and Long-Term Reliability PDF Author: Tae Mok Gwon
Publisher: Springer
ISBN: 9811304726
Category : Technology & Engineering
Languages : en
Pages : 107

Book Description
This book describes the design, fabrication and evaluation of a polymer-based neural interface for a cochlear electrode array, reviewed in terms of fabrication process, functionality, and reliability. Polymer-based devices have attracted attention in the neural prosthetic field due to their flexibility and compatibility with micro-fabrication process. A liquid crystal polymer (LCP) is an inert, highly water-resistant polymer suitable for the encapsulation of electronic components and as a substrate material for fabricating neural interfaces. The author has designed, fabricated, and evaluated an LCP-based cochlear electrode array for an improved polymer-based cochlear implant. The thesis deals with 3 key topics: atraumatic deep insertion, tripolar stimulation, and long-term reliability. Atraumatic insertion of the intracochlear electrode and resulting preservation of residual hearing have become essential in state–of-the-art cochlear implantation. A novel tapered design of an LCP-based cochlear electrode array is presented to meet such goals. For high-density and pitch-recognizable cochlear implant, channel interaction should be avoided. Local tripolar stimulation using multi-layered electrode sites are shown to achieve highly focused electrical stimulation. This thesis addresses another vital issue in the polymer-based neural implants: the long-term reliability issue. After suggesting a new method of forming mechanical interlocking to improve polymer-metal adhesion, the author performs accelerating aging tests to verify the method’s efficacy. The aforementioned three topics have been thoroughly examined through various in vitro and in vivo studies. Verification foresees the development of LCP-based cochlear electrode array for an atraumatic deep insertion, advanced stimulation, and long-term clinical implant.

Deep Brain Stimulation Management

Deep Brain Stimulation Management PDF Author: William J. Marks, Jr
Publisher: Cambridge University Press
ISBN: 1107084253
Category : Medical
Languages : en
Pages : 251

Book Description
Essential reference guide for clinicians working with DBS patients, fully revised throughout with new chapters on epilepsy and psychiatric disorders.

Auditory Prostheses

Auditory Prostheses PDF Author: Fan-Gang Zeng
Publisher: Springer Science & Business Media
ISBN: 1441994343
Category : Medical
Languages : en
Pages : 397

Book Description
Cochlear implants are currently the standard treatment for profound sensorineural hearing loss. In the last decade, advances in auditory science and technology have not only greatly expanded the utility of electric stimulation to other parts of the auditory nervous system in addition to the cochlea, but have also demonstrated drastic changes in the brain in responses to electric stimulation, including changes in language development and music perception. Volume 20 of SHAR focused on basic science and technology underlying the cochlear implant. However, due to the newness of the ideas and technology, the volume did not cover any emerging applications such as bilateral cochlear implants, combined acoustic-electric stimulation, and other types of auditory prostheses, nor did it review brain plasticity in responses to electric stimulation and its perceptual and language consequences. This proposed volume takes off from Volume 20, and expands the examination of implants into new and highly exciting areas. This edited book starts with an overview and introduction by Dr. Fan-Gang Zeng. Chapters 2-9 cover technological development and the advances in treating the full spectrum of ear disorders in the last ten years. Chapters 10-15 discuss brain responses to electric stimulation and their perceptual impact. This volume is particularly exciting because there have been quantum leap from the traditional technology discussed in Volume 20. Thus, this volume is timely and will be of real importance to the SHAR audience.

Implantable Neural Prostheses 1

Implantable Neural Prostheses 1 PDF Author: David Zhou
Publisher: Springer Science & Business Media
ISBN: 0387772618
Category : Technology & Engineering
Languages : en
Pages : 391

Book Description
Significant progress has been made in the development of neural prostheses to restore human functions and improve the quality of human life. Biomedical engineers and neuroscientists around the world are working to improve design and performance of existing devices and to develop novel devices for artificial vision, artificial limbs, and brain–machine interfaces. This book, Implantable Neural Prostheses 1: Devices and Applications,ispart one of a two-book series and describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices and their applications. Devices covered include sensory prosthetic devices, such as visual implants, cochlear implants, auditory midbrain implants, and spinal cord stimulators. Motor prosthetic devices, such as deep brain stimulators, Bion microstimu- tors, the brain control and sensing interface, and cardiac electro-stimulation devices are also included. Progress in magnetic stimulation that may offer a non-invasive approach to prosthetic devices is introduced. Regulatory approval of implantable medical devices in the United States and Europe is also discussed.

Active Middle Ear Implants

Active Middle Ear Implants PDF Author: Klaus Böheim
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805594704
Category : Medical
Languages : en
Pages : 95

Book Description
In recent years, methods for coupling active implants to the middle ear, round window or combinations of passive middle ear prostheses have progressed considerably. Patient selection criteria have expanded from purely sensorineural hearing losses to conductive and mixed hearing losses in difficult-to-treat ears. This book takes into consideration recently developed methods as well as devices in current use. It begins with a fascinating and authentic history of active middle ear implants, written by one of the main pioneers in the field. In the following chapters, leading scientists and clinicians discuss the relevant topics in otology and audiology. Treatments for sensorineural hearing loss, conductive and mixed hearing losses, and results on alternative coupling sites such as the stapes footplate and the oval window are also covered, as well as articles on candidacy and cost-effectiveness. This publication is a must for ENT professionals and surgeons seeking out the latest knowledge on current research and clinical applications of active middle ear implants for all types of hearing loss.

Translational Research in Audiology, Neurotology, and the Hearing Sciences

Translational Research in Audiology, Neurotology, and the Hearing Sciences PDF Author: Colleen G. Le Prell
Publisher: Springer
ISBN: 9783319408460
Category : Medical
Languages : en
Pages : 0

Book Description
Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.

Implantable Electronic Medical Devices

Implantable Electronic Medical Devices PDF Author: Dennis Fitzpatrick
Publisher: Elsevier
ISBN: 012416577X
Category : Technology & Engineering
Languages : en
Pages : 194

Book Description
Implantable Electronic Medical Devices provides a thorough review of the application of implantable devices, illustrating the techniques currently being used together with overviews of the latest commercially available medical devices. This book provides an overview of the design of medical devices and is a reference on existing medical devices. The book groups devices with similar functionality into distinct chapters, looking at the latest design ideas and techniques in each area, including retinal implants, glucose biosensors, cochlear implants, pacemakers, electrical stimulation therapy devices, and much more. Implantable Electronic Medical Devices equips the reader with essential background knowledge on the application of existing medical devices as well as providing an introduction to the latest techniques being used. - A catalogue of existing implantable electronic medical devices - Up-to-date information on the design of implantable electronic medical devices - Background information and reviews on the application and design of up-to-date implantable electronic medical devices

Binaural Hearing

Binaural Hearing PDF Author: Ruth Y. Litovsky
Publisher: Springer Nature
ISBN: 3030571009
Category : Medical
Languages : en
Pages : 425

Book Description
The field of Binaural Hearing involves studies of auditory perception, physiology, and modeling, including normal and abnormal aspects of the system. Binaural processes involved in both sound localization and speech unmasking have gained a broader interest and have received growing attention in the published literature. The field has undergone some significant changes. There is now a much richer understanding of the many aspects that comprising binaural processing, its role in development, and in success and limitations of hearing-aid and cochlear-implant users. The goal of this volume is to provide an up-to-date reference on the developments and novel ideas in the field of binaural hearing. The primary readership for the volume is expected to be academic specialists in the diverse fields that connect with psychoacoustics, neuroscience, engineering, psychology, audiology, and cochlear implants. This volume will serve as an important resource by way of introduction to the field, in particular for graduate students, postdoctoral scholars, the faculty who train them and clinicians.

Implantable Neuroprostheses for Restoring Function

Implantable Neuroprostheses for Restoring Function PDF Author: Kevin Kilgore
Publisher: Elsevier
ISBN: 1782421092
Category : Medical
Languages : en
Pages : 457

Book Description
Research and developments in neuroprostheses are providing scientists with the potential to greatly improve the lives of individuals who have lost some function. Neuroprostheses can help restore or substitute motor and sensory functions which may have been damaged as a result of injury or disease. However, these minute implantable sensors also provide scientists with challenges. This important new book provides readers with a comprehensive review of neuroprostheses. Chapters in part one are concerned with the fundamentals of these devices. Part two looks at neuroprostheses for restoring sensory function whilst part three addresses neuroprostheses for restoring motor function. The final set of chapters discusses significant considerations concerning these sensors. - Systematic and comprehensive coverage of neuroprostheses - Covers the fundamentals of neuroprostheses, their application in restoring sensory and motor function and an analysis of the future trends - Keen focus on industry needs in the field of biomaterials

Deep Brain Stimulation

Deep Brain Stimulation PDF Author: Peter Bain
Publisher: Oxford University Press
ISBN: 0199543712
Category : Medical
Languages : en
Pages : 227

Book Description
This handbook provides an overview of the use of deep brain stimulation (DBS) for the treatment of movement disorders as well as an introduction to the developing area of DBS for the management of psychiatric disease.