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A Genetic Switch

A Genetic Switch PDF Author: Mark Ptashne
Publisher: CSHL Press
ISBN: 9780879697167
Category : Medical
Languages : en
Pages : 172

Book Description
The first edition of Mark Ptashne's 1986 book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This edition is a reprint of the original text, together with a new chapter updating the story to 2004. Among the striking new developments are recent findings on long–range interactions between proteins bound to widely separated sites on the phage genome, and a detailed description of how gene activation works.

A Genetic Switch

A Genetic Switch PDF Author: Mark Ptashne
Publisher: CSHL Press
ISBN: 9780879697167
Category : Medical
Languages : en
Pages : 172

Book Description
The first edition of Mark Ptashne's 1986 book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This edition is a reprint of the original text, together with a new chapter updating the story to 2004. Among the striking new developments are recent findings on long–range interactions between proteins bound to widely separated sites on the phage genome, and a detailed description of how gene activation works.

Photochemistry

Photochemistry PDF Author: Angelo Albini
Publisher: Royal Society of Chemistry
ISBN: 1788013190
Category : Science
Languages : en
Pages : 237

Book Description
Drawing on the continued wealth of photochemical research, this volume combines reviews in the latest advances in the field with specific topical highlights. Starting with periodical reports of the literature from 2015-2016 on physical and inorganic aspects, light induced reactions in cryogenic matrices, triplet states on polymers and related materials, properties of transition-metal compounds and the exploitation of solar energy. Coverage continues with highlighted topics in the second part from photoredox systems for building C-C bonds from carbon dioxide, photochemistry in art, photoresponsive devices targeting nucleic acid structures, developments in photodynamic therapy devices and photocatalysis with donor-acceptor polymers. Providing critical analysis of the topics, this book is essential reading for anyone wanting to keep up to date with the literature on photochemistry and its applications.

Structural Chemistry and Molecular Biology

Structural Chemistry and Molecular Biology PDF Author: Alexander Rich
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 954

Book Description


DNA-Protein Interactions

DNA-Protein Interactions PDF Author: Andrew Arthur Travers
Publisher: Springer Science & Business Media
ISBN: 9780412259906
Category : Medical
Languages : en
Pages : 194

Book Description
The binding of proteins to DNA and the manipulation of DNA by proteins are crucial aspects of the biological role of DNA in the living cell. This book provides a comprehensive and lucid discussion of the molecular interactions involved.

Kernel Methods in Computational Biology

Kernel Methods in Computational Biology PDF Author: Bernhard Schölkopf
Publisher: MIT Press
ISBN: 9780262195096
Category : Computers
Languages : en
Pages : 428

Book Description
A detailed overview of current research in kernel methods and their application to computational biology.

Fluorescence Correlation Spectroscopy

Fluorescence Correlation Spectroscopy PDF Author: R. Rigler
Publisher: Springer Science & Business Media
ISBN: 3642595421
Category : Science
Languages : en
Pages : 503

Book Description
This is the first book-length treatment of both the theoretical background to fluorescence correlation spectroscopy (FCS) and a variety of applications in various fields of science. The high spatial and temporal resolution of FCS has made it a powerful tool for the analysis of molecular interactions and kinetics, transport properties due to thermal motion, and flow. It contains an essential contribution from Nobel Prize winner M. Eigen, who is credited with inventing FCS.

Innovations in Biomolecular Modeling and Simulations

Innovations in Biomolecular Modeling and Simulations PDF Author: Tamar Schlick
Publisher: Royal Society of Chemistry
ISBN: 1849735042
Category : Science
Languages : en
Pages : 381

Book Description
The chemical and biological sciences face unprecedented opportunities in the 21st century. A confluence of factors from parallel universes - advances in experimental techniques in biomolecular structure determination, progress in theoretical modeling and simulation for large biological systems, and breakthroughs in computer technology - has opened new avenues of opportunity as never before. Now, experimental data can be interpreted and further analysed by modeling, and predictions from any approach can be tested and advanced through companion methodologies and technologies. This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts. With contributions from experts in the field, the books describe progress and innovation in areas including: simulation algorithms for dynamics and enhanced configurational sampling, force field development, implicit solvation models, coarse-grained models, quantum-mechanical simulations, protein folding, DNA polymerase mechanisms, nucleic acid complexes and simulations, RNA structure analysis and design and other important topics in structural biology modeling. The books are aimed at graduate students and experts in structural biology and chemistry and the emphasis is on reporting innovative new approaches rather than providing comprehensive reviews on each subject.

Long-Range Control of Gene Expression

Long-Range Control of Gene Expression PDF Author: Veronica van Heyningen
Publisher: Academic Press
ISBN: 0080877818
Category : Science
Languages : en
Pages : 415

Book Description
Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer

Fuzziness

Fuzziness PDF Author: Monika Fuxreiter
Publisher: Springer Science & Business Media
ISBN: 1461406595
Category : Medical
Languages : en
Pages : 210

Book Description
Detailed characterization of fuzzy interactions will be of central importance for understanding the diverse biological functions of intrinsically disordered proteins in complex eukaryotic signaling networks. In this volume, Peter Tompa and Monika Fuxreiter have assembled a series of papers that address the issue of fuzziness in molecular interactions. These papers provide a broad overview of the phenomenon of fuzziness and provide compelling examples of the central role played by fuzzy interactions in regulation of cellular signaling processes and in viral infectivity. These contributions summarize the current state of knowledge in this new field and will undoubtedly stimulate future research that will further advance our understanding of fuzziness and its role in biomolecular interactions.

Protein-Nucleic Acid Interactions

Protein-Nucleic Acid Interactions PDF Author: Phoebe A. Rice
Publisher: Royal Society of Chemistry
ISBN: 0854042725
Category : Science
Languages : en
Pages : 417

Book Description
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.