Viral Oncology PDF Download

Author: George Klein
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 874

View

Book Description

Author: Mei Hwei Chang
Publisher: Springer Science & Business Media
ISBN: 3642389651
Category : Medical
Languages : en
Pages : 293

View

Book Description
Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer – From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309153689
Category : Medical
Languages : en
Pages : 252

View

Book Description
The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004

View

Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author: Kevin J. Harrington
Publisher: John Wiley & Sons
ISBN: 047098578X
Category : Science
Languages : en
Pages : 432

View

Book Description
In the last decade there has been an explosion of interest in viral therapies for cancer. Viral agents have been developed that are harmless to normal tissues but selectively able to kill cancer cells. These agents have been endowed with additional selectivity and potency through genetic manipulation. Increasingly these viruses are undergoing evaluation in clinical trials, both as single agents and in combination with standard chemotherapy and radiotherapy. This book provides a comprehensive yet succinct overview of the current status of viral therapy of cancer. Chapters coherently present the advances made with individual agents and review the biological and clinical background to a range of viral therapies: structured to proceed from basic science at the bench to the patient’s bedside, they give an up-to-date and realistic evaluation of a therapy’s potential utility for the cancer patient. Presents state of the art knowledge on how viruses can be, and have been, used in novel therapeutic approaches for the treatment of cancer Describes the use of viruses as oncolytic agents, killing cells directly Editors are experts in the field, with experience of both laboratory and clinical research Viral Therapy of Cancer is essential reading for both basic scientists and clinicians with an interest in viral therapy and gene therapy.

Author: Dorothy H. Crawford
Publisher: Oxford University Press, USA
ISBN: 0199653119
Category : Health & Fitness
Languages : en
Pages : 219

View

Book Description
This is the story of the discovery of the first human cancer virus. Through intriguing accounts that include some remarkable characters and individual stories from around the globe - including the UK, Africa, USA, and China - it tells the story of the Epstein-Barr virus and the understanding of its connections to a variety of other diseases.

Author: Harald zur Hausen
Publisher: John Wiley & Sons
ISBN: 3527609296
Category : Medical
Languages : en
Pages : 531

View

Book Description
Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.

Author: Alecsandru Ioan Baba
Publisher:
ISBN: 9789732714577
Category : Electronic books
Languages : en
Pages : 787

View

Book Description

Author: P E. Came
Publisher: Springer Science & Business Media
ISBN: 3642684874
Category : Medical
Languages : en
Pages : 580

View

Book Description
" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of action, toxicity, pharmacokinetics, and pharmacodynamics of new agents. The list of clinically effective antiviral agents is expanding and the number of potentially useful compounds is growing rapidly. This book is a combined theoretical text and practical manual which, it is hoped, will be of use to all who have an interest in virus diseases, particularly scientists, physicians and graduate students.

Author: Claudia Cornwall
Publisher: Rowman & Littlefield Publishers
ISBN: 1442215224
Category : Health & Fitness
Languages : en
Pages : 241

View

Book Description
Catching Cancer introduces readers to the investigators who created a medical revolution—a new way of looking at cancer and its causes. Featuring interviews with notable scientists such as Harald zur Hausen, Barry Marshall, Robin Warren, and others, the book tells the story of their struggles, their frustrations, and finally the breakthroughs that helped form some of the most profound changes in the way we view cancer. Claudia Cornwall takes readers inside the lab to reveal the long and winding path to discoveries that have changed and continue to alter the course of medical approaches to one of the most confounding diseases mankind has known. She tells the stories of families who have benefited from this new knowledge, of the researchers who made the revolution happen, and the breakthroughs that continue to change our lives. For years, we’ve thought cancer was the result of lifestyle choices, environmental factors, or genetic mutations. But pioneering scientists have begun to change that picture. We now know that infections cause 20 percent of cancers, including liver, stomach, and cervical cancer, which together kill almost 1.8 million people every year. While the idea that you can catch cancer may sound unsettling, it is actually good news. It means antibiotics and vaccines can be used to combat this most dreaded disease. With this understanding, we have new methods of preventing cancer, and perhaps we may be able to look forward to a day when we will no more fear cancer than we do polio or rubella.