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Vasoplegic Endothelial Dysfunction

Vasoplegic Endothelial Dysfunction PDF Author: Paulo Roberto Barbosa Evora
Publisher: Springer Nature
ISBN: 303074096X
Category : Medical
Languages : en
Pages : 153

Book Description
This unique work presents one of the most significant organ failure condition – cardiocirculatory shock – and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors’ consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients. In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned. Finally, looking for therapeutic alternatives for what we classify as "vasoplegic endothelial dysfunction", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are "wide-spectrum vasopressors", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines. This book ́s translational approach will appeal to a variety of readers within the health specialties of medicine, biomedicine, physiotherapy, nursing, odontology, and basic science.

Vasoplegic Endothelial Dysfunction

Vasoplegic Endothelial Dysfunction PDF Author: Paulo Roberto Barbosa Evora
Publisher: Springer Nature
ISBN: 303074096X
Category : Medical
Languages : en
Pages : 153

Book Description
This unique work presents one of the most significant organ failure condition – cardiocirculatory shock – and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors’ consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients. In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned. Finally, looking for therapeutic alternatives for what we classify as "vasoplegic endothelial dysfunction", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are "wide-spectrum vasopressors", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines. This book ́s translational approach will appeal to a variety of readers within the health specialties of medicine, biomedicine, physiotherapy, nursing, odontology, and basic science.

Endothelium and Cardiovascular Diseases

Endothelium and Cardiovascular Diseases PDF Author: Protasio L. Da Luz
Publisher: Academic Press
ISBN: 0128125519
Category : Medical
Languages : en
Pages : 760

Book Description
Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. - Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information - Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress - Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

Urinary Antiinfectives—Advances in Research and Application: 2012 Edition

Urinary Antiinfectives—Advances in Research and Application: 2012 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1481604635
Category : Medical
Languages : en
Pages : 101

Book Description
Urinary Antiinfectives—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Urinary Antiinfectives. The editors have built Urinary Antiinfectives—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Urinary Antiinfectives in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Urinary Antiinfectives—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Epidemic Preparedness and Control

Epidemic Preparedness and Control PDF Author: Márcia Aparecida Sperança
Publisher: BoD – Books on Demand
ISBN: 0854664041
Category : Medical
Languages : en
Pages : 262

Book Description
Epidemics and pandemics caused by infectious diseases, mainly zoonosis, have existed since the beginning of humanity. They affect health, social, economic, and cultural policies around the world. Epidemic Preparedness and Control highlights epidemiology as an important scientific matter of research on the prevention and control of infectious diseases. It also examines different aspects of public health after the emergence of SARS-CoV-2, the etiological agent of COVID-19. The book is organized into six sections addressing general aspects of pandemics and epidemics as a result of climate change, environmental degradation, socio-cultural interactions and occurrence of zoonoses, and the experience of SARS-CoV-2 contributing to different tools for use in COVID-19 epidemics and other airborne infectious diseases.

Principles and Practice of Critical Care

Principles and Practice of Critical Care PDF Author: P. K. Verma
Publisher: Wolters kluwer india Pvt Ltd
ISBN: 9389335302
Category : Medical
Languages : en
Pages : 724

Book Description
This edition is presented in a totally new and reader-friendly format. The focus of this volume is on holistic management of critically ill adult patients and it builds upon concepts one step at a time – allowing one the opportunity to develop competence at one's own pace.

Cardiac Surgery

Cardiac Surgery PDF Author: Miguel Maluf
Publisher: BoD – Books on Demand
ISBN: 9535112287
Category : Medical
Languages : en
Pages : 191

Book Description
In this book it is shown how this specialty has evolved over the past 20 years, with significant advances in diagnosis and palliative and definitive techniques for correction of cardiovascular diseases. The book contains 10 cahpters, which are showing the classical adult and pediatric cardiac surgery.

Irwin and Rippe's Intensive Care Medicine

Irwin and Rippe's Intensive Care Medicine PDF Author: Richard S. Irwin
Publisher: Lippincott Williams & Wilkins
ISBN: 1975102223
Category : Medical
Languages : en
Pages : 5735

Book Description
With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe’s Intensive Care Medicine offers authoritative guidance to the wide variety of specialty physicians and non-physicians practicing in the adult intensive care environment. This comprehensive textbook covers both the theoretical and practical aspects of the field, and has been completely updated to provide encyclopedic, interprofessional coverage to support practitioners in every area of this complex field.

Irwin and Rippe's Intensive Care Medicine

Irwin and Rippe's Intensive Care Medicine PDF Author: Craig M. Lilly
Publisher: Lippincott Williams & Wilkins
ISBN: 1975181468
Category : Medical
Languages : en
Pages : 7955

Book Description
Covering both the theoretical and practical aspects of critical care,Irwin & Rippe’s Intensive Care Medicine, Ninth Edition, provides state-of-the-art, evidence-based knowledge for specialty physicians and non-physicians practicing in the adult intensive care environment. Drs. Craig M. Lilly, Walter A. Boyle, and Richard S. Irwin, along with a team of expert contributing authors and education expert, William F. Kelly, offer authoritative, comprehensive guidance from an interprofessional, collaborative, educational, and scholarly perspective, encompassing all adult critical care specialties.

Oxford Textbook of Anaesthesia for the Obese Patient

Oxford Textbook of Anaesthesia for the Obese Patient PDF Author: Ashish Sinha
Publisher: Oxford University Press
ISBN: 019875714X
Category : Medical
Languages : en
Pages : 369

Book Description
Obesity is a global public health issue; significant numbers of the world's population are overweight, growing numbers are obese, and many are morbidly obese. As obesity is associated with a range of co-morbidities (namely cardiovascular disease, diabetes, cancer, depression, and sleep apnoea), it presents a daunting peri-operative challenge to the anaesthetist. The increasing size and weight of patients presenting for surgery involves multiple issues from starting intravenous lines through to intubation and ventilation challenges. The Oxford Textbook of Anaesthesia for the Obese Patient is a highly authoritative, evidence-based account of the principles and clinical practice within the field. Across 36 chapters, this resource provides comprehensive coverage of all aspects of the subject including physiological and pharmacological modifications in the obese patient, bariatric and non-bariatric surgery, specific clinical issues such as fluid management and tissue oxygenation, as well as challenges arising from obesity in the setting of paediatrics, obstetrics, intensive care and trauma. Written and edited by experts in the field, this resource is the definitive guide to clinical management of the obese patient, exploring various international approaches to practice, with helpful case studies, and practical advice on common intra-operative challenges, and how to resolve them using evidence and best practice.

Critical Care for Potential Liver Transplant Candidates

Critical Care for Potential Liver Transplant Candidates PDF Author: Dmitri Bezinover
Publisher: Springer
ISBN: 3319929348
Category : Medical
Languages : en
Pages : 238

Book Description
This book focuses on patients with end-stage-liver disease (ESLD) who could possibly qualify for liver transplant. This patient cohort raises many problems: who should be treated and also, when is it too late for transplant? The authors are all dedicated experts in the field of ESLD/liver transplantation, but from different disciplines with different views of the problem. In the past 15 years many things have changed in the treatment for these patients: cardiac assessment, treatment of porto-pulmonary hypertension, hemodynamics, coagulation assessment and management, diagnosis of kidney failure, and the timing of dialysis. These issues are comprehensively discussed in this book, in order to provide physicians starting in the field of transplantation an overview of different areas of concern. This book is aimed at specialists and trainees in critical care, hepatology, anesthesia, surgery, and nephrology.