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Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Kraus Jr.
Publisher: Oxford University Press
ISBN: 0199796513
Category : Medical
Languages : en
Pages : 266

Book Description
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Kraus Jr.
Publisher: Oxford University Press
ISBN: 0199796513
Category : Medical
Languages : en
Pages : 266

Book Description
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Kraus Jr.
Publisher: Oxford University Press
ISBN: 0199347883
Category : Medical
Languages : en
Pages : 266

Book Description
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Henry Kraus (Jr.)
Publisher: Oxford University Press
ISBN: 0199796432
Category : Medical
Languages : en
Pages : 266

Book Description
This book covers topics in NMR/MRI at magnetic fields from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime, with an emphasis on imaging and understanding the human using its applications. Discussion of hardware considerations, relaxation contrast, imaging, artifact correction, and other applications unique to the ULF regime are presented.

Ultra-low Field Nuclear Magnetic Resonance

Ultra-low Field Nuclear Magnetic Resonance PDF Author: Robert H. Kraus (Jr)
Publisher:
ISBN: 9780199349043
Category :
Languages : en
Pages :

Book Description
This text covers topics in NMR/MRI at magnetic fields from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime, with an emphasis on imaging and understanding the human using its applications. Discussion of hardware considerations, relaxation contrast, imaging, artifact correction, and other applications unique to the ULF regime are presented.

Optical Magnetometry

Optical Magnetometry PDF Author: Dmitry Budker
Publisher: Cambridge University Press
ISBN: 1107010357
Category : Science
Languages : en
Pages : 431

Book Description
Comprehensive coverage of the principles, technology and diverse applications of optical magnetometry for graduate students and researchers in atomic physics.

Quantum Magnetic Resonance Imaging Diagnostics of Human Brain Disorders

Quantum Magnetic Resonance Imaging Diagnostics of Human Brain Disorders PDF Author: Madan M Kaila
Publisher: Elsevier
ISBN: 0123847125
Category : Science
Languages : en
Pages : 517

Book Description
Magnetic resonance imaging (MRI) is a medical imaging technique used to visualize detailed internal structure of the body. This book discusses the recent developments in the field of MRI and its application to the diagnosis of human brain disorders. In addition, it reviews the newly emerging concepts and technology, based on the multi-coherence imaging (MQCI). It explains how computer packages can be used to generate images in diseased states and compare them to in vivo results. This will help improve the diagnosis of brain disorders based on the real-time events happening on atomic and molecular quantum levels. This is important since quantum-based MRI would enable clinicians to detect brain tumors at the very early stages. Uses practical examples to explain the techniques - making it easier to understand the concepts Uses diagrams to explain the physics behind the technique - avoiding the use of complicated mathematical formulae

Ultra-low Field Nuclear Magnetic Resonance and Magnetic Resonance Imaging to Discriminate and Identify Materials

Ultra-low Field Nuclear Magnetic Resonance and Magnetic Resonance Imaging to Discriminate and Identify Materials PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description
Method comprising obtaining an NMR measurement from a sample wherein an ultra-low field NMR system probes the sample and produces the NMR measurement and wherein a sampling temperature, prepolarizing field, and measurement field are known; detecting the NMR measurement by means of inductive coils; analyzing the NMR measurement to obtain at least one measurement feature wherein the measurement feature comprises T1, T2, T1.rho., or the frequency dependence thereof; and, searching for the at least one measurement feature within a database comprising NMR reference data for at least one material to determine if the sample comprises a material of interest.

Compact NMR

Compact NMR PDF Author: Bernhard Blümich
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110374587
Category : Technology & Engineering
Languages : en
Pages : 305

Book Description
The goal of this book is to provide an introduction to the practical use of mobile NMR at a level as basic as the operation of a smart phone. Each description follows the same didactic pattern: introduction, basic theory, pulse sequences and parameters, beginners-level measurements, advanced-level measurements, and data processing. Nuclear Magnetic Resonance (NMR) spectroscopy is the most popular method for chemists to analyze molecular structures while Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool for medical doctors that provides high-contrast images of biological tissue depicting the brain function and the beating heart. In both applications large super-conducting magnets are employed which magnetize atomic nuclei of an object positioned inside the magnet. Their circulating motion is interrogated by radio-frequency waves. Depending on the operating mode, the frequency spectrum provides the chemist with molecular information, the medical doctor with anatomic images, while the materials scientist is interested in NMR relaxation parameters, which scale with material properties and determine the contrast in magnetic resonance images. Recent advances in magnet technology led to a variety of small permanent magnets, by which NMR spectra, images, and relaxation parameters can be measured with mobile and low-cost instruments.

Introduction to Functional Magnetic Resonance Imaging

Introduction to Functional Magnetic Resonance Imaging PDF Author: Richard B. Buxton
Publisher: Cambridge University Press
ISBN: 1139481304
Category : Medical
Languages : en
Pages : 479

Book Description
Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.

Zero and Ultra-Low-Field Nuclear Magnetic Resonance Spectroscopy Via Optical Magnetometry

Zero and Ultra-Low-Field Nuclear Magnetic Resonance Spectroscopy Via Optical Magnetometry PDF Author: John Woodland Blanchard
Publisher:
ISBN:
Category :
Languages : en
Pages : 218

Book Description
Nuclear magnetic resonance (NMR) is among the most powerful analytical tools available to the chemical and biological sciences for chemical detection, characterization, and structure elucidation. NMR experiments are usually performed in large magnetic fields in order to maximize sensitivity and increase chemical shift resolution. However, the high magnetic fields required for conventional NMR necessitate large, immobile, and expensive superconducting magnets, limiting the use of the technique. New hyperpolarization and non-inductive detection methods have recently allowed for NMR measurements in the inverse regime of extremely low magnetic fields. Whereas a substantial body of research has been conducted in the high-field regime, taking advantage of the efficient coherent control afforded by a spectroscopy dominated by coupling to the spectrometer, the zero- and ultra-low-field (ZULF) regime has remained mostly unexplored. In this dissertation, we investigate the applicability of ZULF-NMR as a novel spectroscopic technique complimentary to high-field NMR. In particular, we consider various aspects of the ZULF-NMR experiment and the dynamics of nuclear spins under various local spin coupling Hamiltonians. We first survey zero-field NMR experiments on systems dominated by the electron-mediated indirect spin-spin coupling (J-coupling). The resulting J-spectra permit precision measurement of chemically relevant information due to the exquisite sensitivity of J-couplings to subtle changes in molecular geometry and electronic structure. We also consider the effects of weak magnetic fields and residual dipolar couplings in anisotropic media, which encode information about nuclear magnetic moments and geometry, and further resolve topological ambiguities by lifting degeneracies. By extending the understanding of the interactions that contribute to ZULF-NMR spectra, this work represents a significant advancement towards a complete description of zero- and ultra-low-field nuclear magnetic resonance spectroscopy.